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The map label for this gene is pqqL [C]

Identifier: 86751286

GI number: 86751286

Start: 4751319

End: 4752749

Strand: Reverse

Name: pqqL [C]

Synonym: RPB_4179

Alternate gene names: 86751286

Gene position: 4752749-4751319 (Counterclockwise)

Preceding gene: 86751287

Following gene: 86751285

Centisome position: 89.14

GC content: 67.02

Gene sequence:

>1431_bases
ATGCCGGCCCGATCCGATCTCTCCTACCGGGATGATTGCCTCGACATGACCGTATCCGCCTCTCGTCCACGCGCCGCGCT
CGCCATCCTCGCGACGGCGCTGATGCTCGCAGGCCCGGCCGCCGCCCAAACCGCCCCCGCCAATCCACCCGCGACCTTCA
CGCTCGCCAACGGCCTCGACGTTGTGGTGATTCCGGATCGTCGCACCCCGGTGGTGACGCAGATGATCTGGTACAAGGTC
GGCTCCGCCGACGAGACGCCGGGCAAATCCGGACTCGCGCATTTTCTCGAACATCTGATGTTCAAGGGCACAGCCAAGCA
TCCGGCCGGCGAGTTCTCGCAGACCGTGCTGAAGGTCGGCGGCAACGAGAACGCGTTCACCTCGCTCGACTACACCGGCT
ACTATCAGCGCGTGCCGCGCGATCAACTCGACAAGATGATGGCGTTCGAGGCCGACCGCATGACCGGCCTGGTGCTGAAG
GACGAGAACGTGCTGCCGGAGCGCGACGTCGTGCTCGAGGAATACAACATGCGCGTCGCCAATAATCCCGACGCGCGGCT
GACCGAACAGATCATGGCGGCGCTGTATCTCAATCACCCCTATGGCCGCCCTGTGATCGGCTGGCTGCAGGAGATCCAGA
AGCTCGACCGCGAGGACGCGCTGGCGTTCTATCGCCGCTTCTACGCGCCCAACAACGCCACGCTGGTGATCGCCGGCGAC
GTCGATGCCGAGGCGATCCGGCCGGCGATCGAGCGCACCTACGGCGCGGTGCCGGCGCAGCCGGCGATTGCGCCGCAGCG
GGTGCGGCCGCAGGAGCCGGCGCCGGCCGGGCCGCGCACCGTGACGCTGGCCGATCCGCGGGTCGAGCAGCCGAGCGTGC
GGCGCTATTATCTGGTGCCGTCGGCCCACACCGCGGCGAAGGGCGACAGCCCCGCGCTCGAAGTGCTGGCGCAATTGCTC
GGCGGCGGCAGCAACTCCTATCTCTATCGCGCGCTGGTGATCGACCGGCCGCTCGCGATCAATGTCGGCGCCAACTATCA
GGGCACCGCGCTCGACGACACCCACTTCATCGTCGCGGCGACACCGAAGCCGGGCGTCGAATTCTCCGAGATCGAGAAGG
CGATCGACAATGTGATCGCCGACATCGTGCGCAATCCTGTTCGGTCCGAGGATCTCGAGCGGGTGAAGACGCAGCTGATC
GCCCAGTCGATCTACGCGCAGGACAACCAGACCACGCTGGCGCGCTGGTACGGCGCGGCGCTGACCGCCGGTCTCACCGT
GCAGGACATCCAGAGCTGGCCGCAGCGGATCCGCGCCGTCACCTCGGATCAGGTCCGCGCCGTGGCGCAGCAATTCCTCG
ACCGCAACCGCTCGGTGACCGGCTATCTGGTCAAGGGCACGCTGCCAAAGCCCGAGGAGAAACGCTCGTGA

Upstream 100 bases:

>100_bases
AAGTCAGCAATTGATCCGGGGCCGGTTCGCCCGCCCCCCTGCCGGATTGCTTCGATCTTCCGCCGAGCCGCGCCTTCGAA
CGGCGCGCCTGTAATGCCTG

Downstream 100 bases:

>100_bases
CCATGGCCGTCCCCTCGCTCAAACGCCTGGTGCTCGCAGGCGCCATTGCCCTCGCTGCCGCGCTGCCGGCGACGCCCGGC
TTCGCCGCGGCGAAGATCCA

Product: peptidase M16-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MPARSDLSYRDDCLDMTVSASRPRAALAILATALMLAGPAAAQTAPANPPATFTLANGLDVVVIPDRRTPVVTQMIWYKV
GSADETPGKSGLAHFLEHLMFKGTAKHPAGEFSQTVLKVGGNENAFTSLDYTGYYQRVPRDQLDKMMAFEADRMTGLVLK
DENVLPERDVVLEEYNMRVANNPDARLTEQIMAALYLNHPYGRPVIGWLQEIQKLDREDALAFYRRFYAPNNATLVIAGD
VDAEAIRPAIERTYGAVPAQPAIAPQRVRPQEPAPAGPRTVTLADPRVEQPSVRRYYLVPSAHTAAKGDSPALEVLAQLL
GGGSNSYLYRALVIDRPLAINVGANYQGTALDDTHFIVAATPKPGVEFSEIEKAIDNVIADIVRNPVRSEDLERVKTQLI
AQSIYAQDNQTTLARWYGAALTAGLTVQDIQSWPQRIRAVTSDQVRAVAQQFLDRNRSVTGYLVKGTLPKPEEKRS

Sequences:

>Translated_476_residues
MPARSDLSYRDDCLDMTVSASRPRAALAILATALMLAGPAAAQTAPANPPATFTLANGLDVVVIPDRRTPVVTQMIWYKV
GSADETPGKSGLAHFLEHLMFKGTAKHPAGEFSQTVLKVGGNENAFTSLDYTGYYQRVPRDQLDKMMAFEADRMTGLVLK
DENVLPERDVVLEEYNMRVANNPDARLTEQIMAALYLNHPYGRPVIGWLQEIQKLDREDALAFYRRFYAPNNATLVIAGD
VDAEAIRPAIERTYGAVPAQPAIAPQRVRPQEPAPAGPRTVTLADPRVEQPSVRRYYLVPSAHTAAKGDSPALEVLAQLL
GGGSNSYLYRALVIDRPLAINVGANYQGTALDDTHFIVAATPKPGVEFSEIEKAIDNVIADIVRNPVRSEDLERVKTQLI
AQSIYAQDNQTTLARWYGAALTAGLTVQDIQSWPQRIRAVTSDQVRAVAQQFLDRNRSVTGYLVKGTLPKPEEKRS
>Mature_475_residues
PARSDLSYRDDCLDMTVSASRPRAALAILATALMLAGPAAAQTAPANPPATFTLANGLDVVVIPDRRTPVVTQMIWYKVG
SADETPGKSGLAHFLEHLMFKGTAKHPAGEFSQTVLKVGGNENAFTSLDYTGYYQRVPRDQLDKMMAFEADRMTGLVLKD
ENVLPERDVVLEEYNMRVANNPDARLTEQIMAALYLNHPYGRPVIGWLQEIQKLDREDALAFYRRFYAPNNATLVIAGDV
DAEAIRPAIERTYGAVPAQPAIAPQRVRPQEPAPAGPRTVTLADPRVEQPSVRRYYLVPSAHTAAKGDSPALEVLAQLLG
GGSNSYLYRALVIDRPLAINVGANYQGTALDDTHFIVAATPKPGVEFSEIEKAIDNVIADIVRNPVRSEDLERVKTQLIA
QSIYAQDNQTTLARWYGAALTAGLTVQDIQSWPQRIRAVTSDQVRAVAQQFLDRNRSVTGYLVKGTLPKPEEKRS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=473, Percent_Identity=25.369978858351, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI94538354, Length=222, Percent_Identity=27.9279279279279, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI155969707, Length=232, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24308013, Length=210, Percent_Identity=31.9047619047619, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787770, Length=259, Percent_Identity=28.957528957529, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71999683, Length=417, Percent_Identity=24.4604316546763, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17557500, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146563, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32566665, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994338, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=240, Percent_Identity=29.5833333333333, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323421, Length=204, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357875, Length=437, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646943, Length=437, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 52247; Mature: 52116

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARSDLSYRDDCLDMTVSASRPRAALAILATALMLAGPAAAQTAPANPPATFTLANGLD
CCCCCCCCCCHHHHCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCE
VVVIPDRRTPVVTQMIWYKVGSADETPGKSGLAHFLEHLMFKGTAKHPAGEFSQTVLKVG
EEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
GNENAFTSLDYTGYYQRVPRDQLDKMMAFEADRMTGLVLKDENVLPERDVVLEEYNMRVA
CCCCCEEECCCCCHHHHCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCEEEC
NNPDARLTEQIMAALYLNHPYGRPVIGWLQEIQKLDREDALAFYRRFYAPNNATLVIAGD
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECC
VDAEAIRPAIERTYGAVPAQPAIAPQRVRPQEPAPAGPRTVTLADPRVEQPSVRRYYLVP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEC
SAHTAAKGDSPALEVLAQLLGGGSNSYLYRALVIDRPLAINVGANYQGTALDDTHFIVAA
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCEECCCEEEEEE
TPKPGVEFSEIEKAIDNVIADIVRNPVRSEDLERVKTQLIAQSIYAQDNQTTLARWYGAA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LTAGLTVQDIQSWPQRIRAVTSDQVRAVAQQFLDRNRSVTGYLVKGTLPKPEEKRS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCC
>Mature Secondary Structure 
PARSDLSYRDDCLDMTVSASRPRAALAILATALMLAGPAAAQTAPANPPATFTLANGLD
CCCCCCCCCHHHHCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCE
VVVIPDRRTPVVTQMIWYKVGSADETPGKSGLAHFLEHLMFKGTAKHPAGEFSQTVLKVG
EEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
GNENAFTSLDYTGYYQRVPRDQLDKMMAFEADRMTGLVLKDENVLPERDVVLEEYNMRVA
CCCCCEEECCCCCHHHHCCHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCEEEC
NNPDARLTEQIMAALYLNHPYGRPVIGWLQEIQKLDREDALAFYRRFYAPNNATLVIAGD
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECC
VDAEAIRPAIERTYGAVPAQPAIAPQRVRPQEPAPAGPRTVTLADPRVEQPSVRRYYLVP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEC
SAHTAAKGDSPALEVLAQLLGGGSNSYLYRALVIDRPLAINVGANYQGTALDDTHFIVAA
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCEECCCEEEEEE
TPKPGVEFSEIEKAIDNVIADIVRNPVRSEDLERVKTQLIAQSIYAQDNQTTLARWYGAA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LTAGLTVQDIQSWPQRIRAVTSDQVRAVAQQFLDRNRSVTGYLVKGTLPKPEEKRS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]