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The map label for this gene is catB2 [H]

Identifier: 86751191

GI number: 86751191

Start: 4654742

End: 4655407

Strand: Reverse

Name: catB2 [H]

Synonym: RPB_4083

Alternate gene names: 86751191

Gene position: 4655407-4654742 (Counterclockwise)

Preceding gene: 86751196

Following gene: 86751190

Centisome position: 87.32

GC content: 64.71

Gene sequence:

>666_bases
ATGGTCGCAAAAATGCTCTCTGTCGAACCGACGGTGGATCCCTCGGCCCGGCTTCACGAGGTGAAGCTCGGCGCCTATTG
CGAGGTCGGAGCGCGCACGATCCTGAACGAGGTGGCGATGGACGATTACTCCTACGTCGTCAACGACTCGCAGATCACCT
ATTCGAGCATCGGCAAATTCTGCTCGATCGCGGCCATGACCCGGATCAATCCCGGCAATCATCCGATGCATCGCGCGACG
CAGGCGCATTTCACCTATCGCGCCAGCGCGTATTTCGAGGGCGAGAGCGACGATGCGGAGTTCTTCGCCTGGCGCCGCGC
CCACCATGTCCATATCGGCCACGACGTCTGGATCGGCCATGGCGCGATCGTGCTGCCCGGCCGCAACATCGGCACCGGCG
CGGTGGTCGCCGCCGGCGCGATCGTCACCCGCGACGTGCCGGCCTATACGATCGTCGCCGGCAATCCGGCGCGGCCGATC
CGGTGGCGGTTTCCGGAAGTCGTCGCCGAGCGGTTGGCCGAACTGGCGTGGTGGGATTGGGAGCATGAGGCGCTGCGCCT
GGCACTGCCGGATTTTCGCCAGTTGGCGGTGGAGGAATTCCTCGACAAATACGAAGCCGCCGCGAAAATGCGGCGGGGAT
CGCGCAGCAAGGACGTGACGGCATGA

Upstream 100 bases:

>100_bases
TGCCGTTATGCACAGCATGTGCGTGTCATCCCGACGTCACGACGTCGTCACCAAGTCCGCCGAAGAACCTCAGCCTCGAC
AAACCGGATGCGGGGATTCA

Downstream 100 bases:

>100_bases
CCGACATCCTGATCGAAGGCGGCCGCACGCTGCTCGGCGACGAGCTGTCGGAAGCCTCGCTCGAGAGTTCGGGCGGGGTG
ATCGCGGCTGCGGGTTCGAG

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MVAKMLSVEPTVDPSARLHEVKLGAYCEVGARTILNEVAMDDYSYVVNDSQITYSSIGKFCSIAAMTRINPGNHPMHRAT
QAHFTYRASAYFEGESDDAEFFAWRRAHHVHIGHDVWIGHGAIVLPGRNIGTGAVVAAGAIVTRDVPAYTIVAGNPARPI
RWRFPEVVAERLAELAWWDWEHEALRLALPDFRQLAVEEFLDKYEAAAKMRRGSRSKDVTA

Sequences:

>Translated_221_residues
MVAKMLSVEPTVDPSARLHEVKLGAYCEVGARTILNEVAMDDYSYVVNDSQITYSSIGKFCSIAAMTRINPGNHPMHRAT
QAHFTYRASAYFEGESDDAEFFAWRRAHHVHIGHDVWIGHGAIVLPGRNIGTGAVVAAGAIVTRDVPAYTIVAGNPARPI
RWRFPEVVAERLAELAWWDWEHEALRLALPDFRQLAVEEFLDKYEAAAKMRRGSRSKDVTA
>Mature_221_residues
MVAKMLSVEPTVDPSARLHEVKLGAYCEVGARTILNEVAMDDYSYVVNDSQITYSSIGKFCSIAAMTRINPGNHPMHRAT
QAHFTYRASAYFEGESDDAEFFAWRRAHHVHIGHDVWIGHGAIVLPGRNIGTGAVVAAGAIVTRDVPAYTIVAGNPARPI
RWRFPEVVAERLAELAWWDWEHEALRLALPDFRQLAVEEFLDKYEAAAKMRRGSRSKDVTA

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=52, Percent_Identity=55.7692307692308, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=73, Percent_Identity=43.8356164383562, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24662; Mature: 24662

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKMLSVEPTVDPSARLHEVKLGAYCEVGARTILNEVAMDDYSYVVNDSQITYSSIGKF
CCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHH
CSIAAMTRINPGNHPMHRATQAHFTYRASAYFEGESDDAEFFAWRRAHHVHIGHDVWIGH
HHHHHHEEECCCCCCHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHCEEEECCEEEEEC
GAIVLPGRNIGTGAVVAAGAIVTRDVPAYTIVAGNPARPIRWRFPEVVAERLAELAWWDW
CEEEECCCCCCCCHHHHHCCCEECCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHCCCC
EHEALRLALPDFRQLAVEEFLDKYEAAAKMRRGSRSKDVTA
CCHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVAKMLSVEPTVDPSARLHEVKLGAYCEVGARTILNEVAMDDYSYVVNDSQITYSSIGKF
CCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCEEEHHHHHHH
CSIAAMTRINPGNHPMHRATQAHFTYRASAYFEGESDDAEFFAWRRAHHVHIGHDVWIGH
HHHHHHEEECCCCCCHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHCEEEECCEEEEEC
GAIVLPGRNIGTGAVVAAGAIVTRDVPAYTIVAGNPARPIRWRFPEVVAERLAELAWWDW
CEEEECCCCCCCCHHHHHCCCEECCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHCCCC
EHEALRLALPDFRQLAVEEFLDKYEAAAKMRRGSRSKDVTA
CCHHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]