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The map label for this gene is paaJ [C]

Identifier: 86751186

GI number: 86751186

Start: 4649272

End: 4650456

Strand: Reverse

Name: paaJ [C]

Synonym: RPB_4078

Alternate gene names: 86751186

Gene position: 4650456-4649272 (Counterclockwise)

Preceding gene: 86751189

Following gene: 86751185

Centisome position: 87.22

GC content: 67.51

Gene sequence:

>1185_bases
ATGGCGTCATCCGTCTACGTCGCCGGTGTCGGCATGATTCCTTTCGTCAAGCCGGGCGCCAACGAGCCCTATCACCTGAT
GGGCGCCGAAGCGGCGCGGCGCGCGCTCAGCGACGCGGGTGTCGGCTACGACGCCATCCAGCAGGCCTTCGTCGGCTACG
TTTACGGCGACTCCACCTGCGGGCAGCGCGCGCTGTATCAGGTCGGCATGACCGGCGTGCCGATCGTCAACGTCAACAAC
AACTGCTCGACCGGCTCGACCGCGCTGTTTCTGGCGCGGCAGGCGATCGCCTCGGGTGCGGCCGATTGCGTGCTGGCGCT
CGGCTTCGAGCAGATGAAGCCCGGTGCGCTCGGCTCGGTGTTCGTCGATCGCCCCAGCGCGTTCGAGGATTTCGATGCCG
CCGCCGACAAGTTGATCGATGCGCCCGGCATTCCGCTGGCGCTGCGCTATTTCGGCGGCGCCGGCCTCAGCCACATGCAG
AAGCACGGCACGCCGCTGTCGTCCTTCGCCAAGGTCCGCGCCAAAGCGAGCCGCCACGCCGCGAAAAATCCGCTGGCGTT
GTTCCGCAAGGAAGTCACCGCGGAGGACGTGCTGAACGACCAGGTGATCTGGCCCGGCGTGATGACGCGGCTGATGGCGT
GCCCGCCGACCTGCGGCGGTGCCGCGGCTGTGCTGGTGTCGGAAGCCTTCGCCAAGAAGCACGGCCTCAACATCAACGTC
CGCATCGCTGCGCAAGCAATGACAACCGACACGCCCTCGACATTCGACGCGGGCGACATGATGCGGGTGGTCGGCTACGA
CATGGCGCGTGCCGCGGCCGACAAGGTCTACGAGCAGGCCGGCGTGGGCCCGAAGGACATCGACGTCGTCGAGCTGCACG
ACTGCTTCGCCCACAACGAGTTGATCACCTACGAGGCGCTCGGCCTGTGCCCCGAAGGCGGCGCCGAGAAGTTCATCGAC
GACGGCGACAACACCTATGGCGGCCAATTCGTCACCAATCCGTCCGGCGGGTTGCTGTCGAAAGGCCATCCGCTCGGCGC
CACCGGGCTCGCGCAGTGCTACGAACTGACCCGGCAGTTGCGCGGCTCCGCGGAGGCGACGCAGGTGGACGGCGCGAAGC
GCGCGCTGCAGCACAATCTCGGCCTCGGCGGGGCTTGCGTCGTCACCCTTTACGAACGCGCCTGA

Upstream 100 bases:

>100_bases
TCATGCATCCGTGAAGCGTCGCCGATTGACTCCAGCGACGGTGGCTTATATTACTCATGGGTAATAAAAAGTCCAACGGG
TAAGTTAGGGAGAGAAACAA

Downstream 100 bases:

>100_bases
GGCGACGCTCATGGTTGATCAATCCGCGGTCGGTCGCCGGTTCACGCCGGTGACGGCCCAAGTCGAGCCGGGCCGTCTGC
GCTATTTTTTCGAGACGCTC

Product: lipid-transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MASSVYVAGVGMIPFVKPGANEPYHLMGAEAARRALSDAGVGYDAIQQAFVGYVYGDSTCGQRALYQVGMTGVPIVNVNN
NCSTGSTALFLARQAIASGAADCVLALGFEQMKPGALGSVFVDRPSAFEDFDAAADKLIDAPGIPLALRYFGGAGLSHMQ
KHGTPLSSFAKVRAKASRHAAKNPLALFRKEVTAEDVLNDQVIWPGVMTRLMACPPTCGGAAAVLVSEAFAKKHGLNINV
RIAAQAMTTDTPSTFDAGDMMRVVGYDMARAAADKVYEQAGVGPKDIDVVELHDCFAHNELITYEALGLCPEGGAEKFID
DGDNTYGGQFVTNPSGGLLSKGHPLGATGLAQCYELTRQLRGSAEATQVDGAKRALQHNLGLGGACVVTLYERA

Sequences:

>Translated_394_residues
MASSVYVAGVGMIPFVKPGANEPYHLMGAEAARRALSDAGVGYDAIQQAFVGYVYGDSTCGQRALYQVGMTGVPIVNVNN
NCSTGSTALFLARQAIASGAADCVLALGFEQMKPGALGSVFVDRPSAFEDFDAAADKLIDAPGIPLALRYFGGAGLSHMQ
KHGTPLSSFAKVRAKASRHAAKNPLALFRKEVTAEDVLNDQVIWPGVMTRLMACPPTCGGAAAVLVSEAFAKKHGLNINV
RIAAQAMTTDTPSTFDAGDMMRVVGYDMARAAADKVYEQAGVGPKDIDVVELHDCFAHNELITYEALGLCPEGGAEKFID
DGDNTYGGQFVTNPSGGLLSKGHPLGATGLAQCYELTRQLRGSAEATQVDGAKRALQHNLGLGGACVVTLYERA
>Mature_393_residues
ASSVYVAGVGMIPFVKPGANEPYHLMGAEAARRALSDAGVGYDAIQQAFVGYVYGDSTCGQRALYQVGMTGVPIVNVNNN
CSTGSTALFLARQAIASGAADCVLALGFEQMKPGALGSVFVDRPSAFEDFDAAADKLIDAPGIPLALRYFGGAGLSHMQK
HGTPLSSFAKVRAKASRHAAKNPLALFRKEVTAEDVLNDQVIWPGVMTRLMACPPTCGGAAAVLVSEAFAKKHGLNINVR
IAAQAMTTDTPSTFDAGDMMRVVGYDMARAAADKVYEQAGVGPKDIDVVELHDCFAHNELITYEALGLCPEGGAEKFIDD
GDNTYGGQFVTNPSGGLLSKGHPLGATGLAQCYELTRQLRGSAEATQVDGAKRALQHNLGLGGACVVTLYERA

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=397, Percent_Identity=55.6675062972292, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI302344760, Length=397, Percent_Identity=52.6448362720403, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI302344767, Length=329, Percent_Identity=55.6231003039514, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI302344762, Length=396, Percent_Identity=47.4747474747475, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI55956775, Length=357, Percent_Identity=44.2577030812325, Blast_Score=272, Evalue=3e-73,
Organism=Escherichia coli, GI1787663, Length=323, Percent_Identity=25.3869969040248, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537653, Length=401, Percent_Identity=45.6359102244389, Blast_Score=330, Evalue=8e-91,
Organism=Drosophila melanogaster, GI24585051, Length=392, Percent_Identity=54.8469387755102, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI19921506, Length=392, Percent_Identity=53.8265306122449, Blast_Score=430, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 41228; Mature: 41097

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSVYVAGVGMIPFVKPGANEPYHLMGAEAARRALSDAGVGYDAIQQAFVGYVYGDSTC
CCCCEEEEEECCCCEECCCCCCCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCH
GQRALYQVGMTGVPIVNVNNNCSTGSTALFLARQAIASGAADCVLALGFEQMKPGALGSV
HHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCHHHCCCCCCCEE
FVDRPSAFEDFDAAADKLIDAPGIPLALRYFGGAGLSHMQKHGTPLSSFAKVRAKASRHA
EECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
AKNPLALFRKEVTAEDVLNDQVIWPGVMTRLMACPPTCGGAAAVLVSEAFAKKHGLNINV
CCCCHHHHHHHHHHHHHHCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEE
RIAAQAMTTDTPSTFDAGDMMRVVGYDMARAAADKVYEQAGVGPKDIDVVELHDCFAHNE
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHCCC
LITYEALGLCPEGGAEKFIDDGDNTYGGQFVTNPSGGLLSKGHPLGATGLAQCYELTRQL
EEEEHHHCCCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGSAEATQVDGAKRALQHNLGLGGACVVTLYERA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure 
ASSVYVAGVGMIPFVKPGANEPYHLMGAEAARRALSDAGVGYDAIQQAFVGYVYGDSTC
CCCEEEEEECCCCEECCCCCCCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCH
GQRALYQVGMTGVPIVNVNNNCSTGSTALFLARQAIASGAADCVLALGFEQMKPGALGSV
HHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCHHHCCCCCCCEE
FVDRPSAFEDFDAAADKLIDAPGIPLALRYFGGAGLSHMQKHGTPLSSFAKVRAKASRHA
EECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
AKNPLALFRKEVTAEDVLNDQVIWPGVMTRLMACPPTCGGAAAVLVSEAFAKKHGLNINV
CCCCHHHHHHHHHHHHHHCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEE
RIAAQAMTTDTPSTFDAGDMMRVVGYDMARAAADKVYEQAGVGPKDIDVVELHDCFAHNE
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHCCC
LITYEALGLCPEGGAEKFIDDGDNTYGGQFVTNPSGGLLSKGHPLGATGLAQCYELTRQL
EEEEHHHCCCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGSAEATQVDGAKRALQHNLGLGGACVVTLYERA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]