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The map label for this gene is ddpA [H]

Identifier: 86751157

GI number: 86751157

Start: 4618620

End: 4620239

Strand: Direct

Name: ddpA [H]

Synonym: RPB_4049

Alternate gene names: 86751157

Gene position: 4618620-4620239 (Clockwise)

Preceding gene: 86751156

Following gene: 86751158

Centisome position: 86.63

GC content: 62.84

Gene sequence:

>1620_bases
ATGAAACGTCGCGACTTCCTGAAATCTGCCACCGCCCTCGCTGCCGGAGCGATGGTGCCGGCGCCCGCGATCTGGTCCGC
TGCGAAGGCGGACGCACGGTCGGAATCCCTGCTGGTGGTGTCCGAAAGCGGCCCCAACAACCTCGACATCCACGGCATCG
GCACCAATGTGCCGGGCTACGAGGTGTCGTGGAATTGCTACGACCGGCTGATCACCCACGAGATGAAGGAAGGCCCCGGC
GGGGTTCCCTATTACGACAAGGACAAGTTCAGGGGCGAACTCGCCGAGGACATGGTGGTCGGCGACATGTCGGCGACCTT
CAAGCTGAAGAAGAACGCCACCTTCCAGGACGGCACCCCGGTCACCGCCAAGGACGTCAAATGGTCGCTCGATCGCTCGG
TCAGCGTCGGCGGCTTCCCGACCTTCCAGATGAGCGCCGGCTCGCTGACCAAGCCCGAGCAGTTCGTCGTCGTCGACGAC
CACACCGTGCGGGTCGACTTTCTCCGCAAGGACAAGCTGACGATCCCGGATCTCGCGGTGATCGTGCCCTGCGTCGTCAA
TTCCGAACTGGTGAAGAAGAACGCCACCGAGAAGGATCCGTGGGGCCTCGAATACACCAAGCAGAACACCGCCGGCTCCG
GCGCCTACCGCGTGGTCAAGTGGACCGCCGGCACCGAAGTGATCATGGAGCGCAACGACAAATGGGTCGGCGGCCCGCTG
CCGAAGATCAAGCGCGTGATCTGGCGCATGGTGCCGCAGGCCGGCAACCGCCGCGCCCTGCTGGAGCGCGGCGACGCCGA
CATCTCCTATGAGTTGCCGAACCAGGACTTCGCCGAGATGAAGCGCGACGGCAAGATCAACGTGGTGTCGCTGCCGATCT
CGAACGGCATCCAGTATCTCGGCATGAACGTCACCCAGCCGCCGTTCAACAATCCCAAGGTGCGCGAGGCGGTGGCCTAT
GCGGTGCCGTATCAGAAGATCATCGACGCGGTGATGTTCGGCCTCGCCAATCCGATGTTCGGGGCGGCCGCCGACAAGGC
GACCGAAGTGAAGTGGCCGCAGCCGACCAAGTACAATACCGACATCGCCAAGGCCAAGGCGCTGATGGCGGAAGCCGGCT
ACGCCGGCGGCTTCGACACCACGCTGTCGTTCGACCTCGGCTTCGCCGGCGTCAACGAGCCGATGTGCATCCTGATCCAG
GAGAGTCTCGCGCAGATCGGCATCCGCTGCACGATCAACAAGATCCCCGGCGCCAACTGGCGCACCGAGTTGAACAAGAA
GGTGCTGCCGCTCTACGTCAACATCTTTTCGGGATGGCTCGATTACCCGGAATACTTCTTCTACTGGTGCTACCGCTCCG
GCAATTCGATCTTCAACACCATGAACTACAACTCGCCCGATATGGACAAGCTGATCGAAGGCGCCCGCGTCGCCGCGGCG
GCCGGCGACATGCCGACCTACGACACCGACGTCAAGGGCTTCGTCGATCTGGCCTTCAAGGACATCCCGCGCGTGCCTTT
GTATCAGCCCTATCTCAACGTCGCGATGCAGAAGAACATCTCCGGCTTCGCCTACTGGTTCCACCGCCGGCTGGACTACC
GGACGATGGTGAAGGGCTGA

Upstream 100 bases:

>100_bases
CTTTTCAAGAGCTTGAGCTGATCCTAGGGCGCTGCTCCGCGACTGGCATGAAGTTTGCGATCCAGGTTCCGAGTCGACCC
CTCGTGCCCTGGAGCGTTGT

Downstream 100 bases:

>100_bases
GCATGTCGGTGCCGACCGCCCTGCACAGCGCCGTCATCCTGAGGTGCGCGCCCTTGCGCGCCTCGAAGGATGCGGCGTCA
AGCAGTGCCTCTGAACCATC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSESLLVVSESGPNNLDIHGIGTNVPGYEVSWNCYDRLITHEMKEGPG
GVPYYDKDKFRGELAEDMVVGDMSATFKLKKNATFQDGTPVTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDD
HTVRVDFLRKDKLTIPDLAVIVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKINVVSLPISNGIQYLGMNVTQPPFNNPKVREAVAY
AVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNTDIAKAKALMAEAGYAGGFDTTLSFDLGFAGVNEPMCILIQ
ESLAQIGIRCTINKIPGANWRTELNKKVLPLYVNIFSGWLDYPEYFFYWCYRSGNSIFNTMNYNSPDMDKLIEGARVAAA
AGDMPTYDTDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNISGFAYWFHRRLDYRTMVKG

Sequences:

>Translated_539_residues
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSESLLVVSESGPNNLDIHGIGTNVPGYEVSWNCYDRLITHEMKEGPG
GVPYYDKDKFRGELAEDMVVGDMSATFKLKKNATFQDGTPVTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDD
HTVRVDFLRKDKLTIPDLAVIVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKINVVSLPISNGIQYLGMNVTQPPFNNPKVREAVAY
AVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNTDIAKAKALMAEAGYAGGFDTTLSFDLGFAGVNEPMCILIQ
ESLAQIGIRCTINKIPGANWRTELNKKVLPLYVNIFSGWLDYPEYFFYWCYRSGNSIFNTMNYNSPDMDKLIEGARVAAA
AGDMPTYDTDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNISGFAYWFHRRLDYRTMVKG
>Mature_539_residues
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSESLLVVSESGPNNLDIHGIGTNVPGYEVSWNCYDRLITHEMKEGPG
GVPYYDKDKFRGELAEDMVVGDMSATFKLKKNATFQDGTPVTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDD
HTVRVDFLRKDKLTIPDLAVIVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKINVVSLPISNGIQYLGMNVTQPPFNNPKVREAVAY
AVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNTDIAKAKALMAEAGYAGGFDTTLSFDLGFAGVNEPMCILIQ
ESLAQIGIRCTINKIPGANWRTELNKKVLPLYVNIFSGWLDYPEYFFYWCYRSGNSIFNTMNYNSPDMDKLIEGARVAAA
AGDMPTYDTDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNISGFAYWFHRRLDYRTMVKG

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=510, Percent_Identity=27.6470588235294, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787052, Length=450, Percent_Identity=26.2222222222222, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789966, Length=440, Percent_Identity=27.0454545454545, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787495, Length=531, Percent_Identity=24.8587570621469, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787551, Length=342, Percent_Identity=24.8538011695906, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789887, Length=232, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59963; Mature: 59963

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSESLLVVSESGPNNLDIHGIGTNVPGY
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCE
EVSWNCYDRLITHEMKEGPGGVPYYDKDKFRGELAEDMVVGDMSATFKLKKNATFQDGTP
EEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCC
VTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDDHTVRVDFLRKDKLTIPDLAV
CCHHCCEEECCCCEECCCCCEEEECCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCHHH
IVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
HHHHHCCHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCH
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKINVVSLPISNGIQYL
HHHHHHHHHHCCCCCCCEEHEECCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCEEE
GMNVTQPPFNNPKVREAVAYAVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNT
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DIAKAKALMAEAGYAGGFDTTLSFDLGFAGVNEPMCILIQESLAQIGIRCTINKIPGANW
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHCCEEEEEECCCCCCC
RTELNKKVLPLYVNIFSGWLDYPEYFFYWCYRSGNSIFNTMNYNSPDMDKLIEGARVAAA
HHHCCCCEEHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHCCCCEEEE
AGDMPTYDTDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNISGFAYWFHRRLDYRTMVKG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MKRRDFLKSATALAAGAMVPAPAIWSAAKADARSESLLVVSESGPNNLDIHGIGTNVPGY
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCE
EVSWNCYDRLITHEMKEGPGGVPYYDKDKFRGELAEDMVVGDMSATFKLKKNATFQDGTP
EEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCC
VTAKDVKWSLDRSVSVGGFPTFQMSAGSLTKPEQFVVVDDHTVRVDFLRKDKLTIPDLAV
CCHHCCEEECCCCEECCCCCEEEECCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCHHH
IVPCVVNSELVKKNATEKDPWGLEYTKQNTAGSGAYRVVKWTAGTEVIMERNDKWVGGPL
HHHHHCCHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCH
PKIKRVIWRMVPQAGNRRALLERGDADISYELPNQDFAEMKRDGKINVVSLPISNGIQYL
HHHHHHHHHHCCCCCCCEEHEECCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCEEE
GMNVTQPPFNNPKVREAVAYAVPYQKIIDAVMFGLANPMFGAAADKATEVKWPQPTKYNT
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DIAKAKALMAEAGYAGGFDTTLSFDLGFAGVNEPMCILIQESLAQIGIRCTINKIPGANW
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHHCCEEEEEECCCCCCC
RTELNKKVLPLYVNIFSGWLDYPEYFFYWCYRSGNSIFNTMNYNSPDMDKLIEGARVAAA
HHHCCCCEEHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCHHHHHCCCCEEEE
AGDMPTYDTDVKGFVDLAFKDIPRVPLYQPYLNVAMQKNISGFAYWFHRRLDYRTMVKG
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]