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The map label for this gene is mmgC [H]

Identifier: 86751043

GI number: 86751043

Start: 4489951

End: 4491126

Strand: Direct

Name: mmgC [H]

Synonym: RPB_3935

Alternate gene names: 86751043

Gene position: 4489951-4491126 (Clockwise)

Preceding gene: 86751042

Following gene: 86751044

Centisome position: 84.21

GC content: 64.29

Gene sequence:

>1176_bases
ATGAAACATCATGCCGCCGCGGAGCAGGACGAATTCCACGACATCCGCGACGCCGTCGCCAAACTGTGTTCGCAGTTCCC
CGGCGAATATTGGCGCAAGCTCGACCGCGAGATGGCCTACCCGCAGGCCTTCGTCGACGCGCTGACCACCGCCGGCTATC
TGTCGGTGCTGATCCCCGAGGAATACGGCGGCGCCGGGCTGAAGCTGTCGGCCGCGGCGGCGATCCTGGAAGAGATCCAG
CGCGCCGGCTGCAACGGCGGCGGCTGCCACGCCCAGATGTACACCATGGGCACGCTGCTGCGGCACGGCTCCGACGAGCA
GAAGGCGAAGTGGCTGCCGAAGGTCGCCTCCGGTGAATTGCGGCTGCAGGCGTTCGGCGTCACCGAGCCGACCTCGGGCA
CCGACACCACCTCGCTGAAGACCTTCGCCAAGAAGGACGACAACGGCGACTACGTCGTCAACGGCCAGAAGATCTGGACC
AGCCGCGCCGAATATTCCGATCTGATGATCCTCTTGGCGCGCACCACGCCGAAGGATCAGGCGGCGAAGAAGACCGAGGG
CCTGTCGGTGTTCCTGGTCGACATGCGCGAAGCGCGCGGCCATGGGCTGGAGATCCGCCCGATCCGCACCATGATGAACC
ACGCCACCACCGAAGTGTTCTTCACCGACCTCAAGGTGCCGAAGGAAAATCTGATCGGCGAGGAAGGCAAGGGCTTCCGC
TACATCCTCTCCGGCATGAACGCCGAGCGCATCCTGATCGCGGCGGAATGCGTCGGCGACGCCAAATGGTTCATCGCCAA
GGCCTCGAACTACGCCAAGGACCGCACGGTGTTCGGCCGGCCGATCGGCCAGAACCAGGGCATCCAGTTTCCGATCGCCA
AGGCCTACGCCAACATGCGCGCGGCCGAGCTGATGGTGAAGGAAGCGACGCGGAAGTACGAAGCCGGCATGGATTGCGGC
GCCGAGGCCAACATGGCCAAGATGCTCGCCGCTGATGCCTCGTTCGAGGCCGCCAATGCCTGCATTCAAACCCATGGTGG
CTTCGGCTTCGCCGAGGAATACGACGTCGAACGCAAATTCCGCGAAACGCGCCTCTATCAGGTCGCGCCGATCTCCACCA
ACCTGATCCTGTCGCATCTCGCCGAGCACGTGCTCGGCATGCCGCGGTCGTATTGA

Upstream 100 bases:

>100_bases
CGGGGAGCCGAAGCGGGTGTATTCGAGCTTCGTCAAGGGCTACGAGTCCTTGCCGGTTCGCATCTCATGACCCCCTAAGA
AAAAGAAGACAGCCTCCAAA

Downstream 100 bases:

>100_bases
GGGCGGGTCATGCTGATCAGCTTCGGAAAGATGCGCGCTCGCCACGAGTCGCAGCGAGCTCCCTCGCCCCGCTCTTCGCG
GGGAGAGGGTCGGGGTGAGG

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKHHAAAEQDEFHDIRDAVAKLCSQFPGEYWRKLDREMAYPQAFVDALTTAGYLSVLIPEEYGGAGLKLSAAAAILEEIQ
RAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKVASGELRLQAFGVTEPTSGTDTTSLKTFAKKDDNGDYVVNGQKIWT
SRAEYSDLMILLARTTPKDQAAKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDLKVPKENLIGEEGKGFR
YILSGMNAERILIAAECVGDAKWFIAKASNYAKDRTVFGRPIGQNQGIQFPIAKAYANMRAAELMVKEATRKYEAGMDCG
AEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSHLAEHVLGMPRSY

Sequences:

>Translated_391_residues
MKHHAAAEQDEFHDIRDAVAKLCSQFPGEYWRKLDREMAYPQAFVDALTTAGYLSVLIPEEYGGAGLKLSAAAAILEEIQ
RAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKVASGELRLQAFGVTEPTSGTDTTSLKTFAKKDDNGDYVVNGQKIWT
SRAEYSDLMILLARTTPKDQAAKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDLKVPKENLIGEEGKGFR
YILSGMNAERILIAAECVGDAKWFIAKASNYAKDRTVFGRPIGQNQGIQFPIAKAYANMRAAELMVKEATRKYEAGMDCG
AEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSHLAEHVLGMPRSY
>Mature_391_residues
MKHHAAAEQDEFHDIRDAVAKLCSQFPGEYWRKLDREMAYPQAFVDALTTAGYLSVLIPEEYGGAGLKLSAAAAILEEIQ
RAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKVASGELRLQAFGVTEPTSGTDTTSLKTFAKKDDNGDYVVNGQKIWT
SRAEYSDLMILLARTTPKDQAAKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDLKVPKENLIGEEGKGFR
YILSGMNAERILIAAECVGDAKWFIAKASNYAKDRTVFGRPIGQNQGIQFPIAKAYANMRAAELMVKEATRKYEAGMDCG
AEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSHLAEHVLGMPRSY

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=29.3650793650794, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI4501857, Length=335, Percent_Identity=33.4328358208955, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI4557233, Length=369, Percent_Identity=31.1653116531165, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI76496475, Length=335, Percent_Identity=34.3283582089552, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI4557235, Length=335, Percent_Identity=34.3283582089552, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI21361497, Length=386, Percent_Identity=30.0518134715026, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI187960098, Length=339, Percent_Identity=30.9734513274336, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557231, Length=339, Percent_Identity=30.9734513274336, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226958412, Length=365, Percent_Identity=28.2191780821918, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=30.6451612903226, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI226958414, Length=359, Percent_Identity=27.8551532033426, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI7669494, Length=333, Percent_Identity=29.4294294294294, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4503943, Length=333, Percent_Identity=29.4294294294294, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI48976061, Length=327, Percent_Identity=26.9113149847095, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI211971008, Length=327, Percent_Identity=26.9113149847095, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38505218, Length=298, Percent_Identity=26.510067114094, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1786223, Length=360, Percent_Identity=29.4444444444444, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081958, Length=360, Percent_Identity=30, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71985184, Length=344, Percent_Identity=32.8488372093023, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=28.4182305630027, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=29.4943820224719, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17534899, Length=351, Percent_Identity=32.7635327635328, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=29.144385026738, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=389, Percent_Identity=28.2776349614396, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17538396, Length=376, Percent_Identity=28.1914893617021, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=313, Percent_Identity=30.3514376996805, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=292, Percent_Identity=32.8767123287671, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=27.7472527472527, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=364, Percent_Identity=26.3736263736264, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=340, Percent_Identity=28.8235294117647, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI32563615, Length=252, Percent_Identity=29.3650793650794, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=304, Percent_Identity=27.3026315789474, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=248, Percent_Identity=29.0322580645161, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=252, Percent_Identity=29.3650793650794, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=310, Percent_Identity=26.1290322580645, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17531913, Length=167, Percent_Identity=27.5449101796407, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=267, Percent_Identity=27.3408239700375, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=267, Percent_Identity=27.3408239700375, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356377, Length=342, Percent_Identity=33.6257309941521, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=31.3157894736842, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24660351, Length=343, Percent_Identity=30.0291545189504, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281363737, Length=330, Percent_Identity=31.5151515151515, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355753, Length=337, Percent_Identity=29.673590504451, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=28.494623655914, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19920834, Length=350, Percent_Identity=28, Blast_Score=111, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43160; Mature: 43160

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHHAAAEQDEFHDIRDAVAKLCSQFPGEYWRKLDREMAYPQAFVDALTTAGYLSVLIPE
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEC
EYGGAGLKLSAAAAILEEIQRAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKVASGEL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCE
RLQAFGVTEPTSGTDTTSLKTFAKKDDNGDYVVNGQKIWTSRAEYSDLMILLARTTPKDQ
EEEEECCCCCCCCCCCHHHHHHHCCCCCCCEEECCCEEECCCCCCCCEEEEEECCCCHHH
AAKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDLKVPKENLIGEEGKGFR
HHHHHCCCEEEEEEEHHHCCCCEEEHHHHHHHHHHHHHEEEEECCCCHHHCCCCCCCCHH
YILSGMNAERILIAAECVGDAKWFIAKASNYAKDRTVFGRPIGQNQGIQFPIAKAYANMR
HHCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHH
AAELMVKEATRKYEAGMDCGAEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKF
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
RETRLYQVAPISTNLILSHLAEHVLGMPRSY
HHHHCEEEECCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKHHAAAEQDEFHDIRDAVAKLCSQFPGEYWRKLDREMAYPQAFVDALTTAGYLSVLIPE
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEC
EYGGAGLKLSAAAAILEEIQRAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKVASGEL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCE
RLQAFGVTEPTSGTDTTSLKTFAKKDDNGDYVVNGQKIWTSRAEYSDLMILLARTTPKDQ
EEEEECCCCCCCCCCCHHHHHHHCCCCCCCEEECCCEEECCCCCCCCEEEEEECCCCHHH
AAKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDLKVPKENLIGEEGKGFR
HHHHHCCCEEEEEEEHHHCCCCEEEHHHHHHHHHHHHHEEEEECCCCHHHCCCCCCCCHH
YILSGMNAERILIAAECVGDAKWFIAKASNYAKDRTVFGRPIGQNQGIQFPIAKAYANMR
HHCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHH
AAELMVKEATRKYEAGMDCGAEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKF
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
RETRLYQVAPISTNLILSHLAEHVLGMPRSY
HHHHCEEEECCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]