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The map label for this gene is maoC [H]

Identifier: 86750746

GI number: 86750746

Start: 4172693

End: 4174729

Strand: Direct

Name: maoC [H]

Synonym: RPB_3636

Alternate gene names: 86750746

Gene position: 4172693-4174729 (Clockwise)

Preceding gene: 86750743

Following gene: 86750752

Centisome position: 78.26

GC content: 67.94

Gene sequence:

>2037_bases
ATGACCACCACGCTGCAAAGCCTCGCGCGCGACGCCTGGGTGACGCCGGACACCGGCCTCGTCGACATTCCGAGCGCGAT
CGACGGCCGAGTGGTGGCGCGCGCCTCCAGCGCCGGGCTCGACTTTGCCGCGATCGTGCGCCACGCGCGCGAGGTCGGCG
GGCCCGGCCTGCGCGCGCTGAGCTTTCACCAGCGCGCCGACCGGCTGAAGGCAATCGGCGCGTATCTGATCGAGCGCAAG
GAGCAGCTCTACGCGATCGCCGCCGACACCGGCGCCAATCGCCGCGACAACGCGATCGACATCGACGGCGGCCTGGTGAC
GCTCGCGGCCTACGCCTCGCGCGGCCGGCGCGAACTGCCGGATACGAAATTCATCATCGAAGGCGAGGTCGAACAATTCG
GCAAGCGCGGCAGCTTCGTCGGGCAACACATTCTCTCACCGCTACACGGCGTCGCCGTGCATATCAACGCGTTCAATTTT
CCGTGCTGGGGTCTGCTCGAAAAGCTGGCGCCGGCGCTGCTCGCCGGCGTCCCGGTGATCGCCAAGCCGGCGACGGCGAC
GGCCTATGTGGCCGAGGCGCTGGTCAAGCTGATCCACGAATCCGGCCTGCTGCCGCCGGGCGCGCTTCAGCTGATCTGTG
GCAGCACCGGCGATCTCTTCGATCATCTGACCGGCCAGGATGTGATCGCCTTCACCGGCTCGATCGAGACCTCGGACAAG
CTCCGCGCGCATCCCAACGTCGCAAGGCATTCGATCCGCTTCATCGCCGAGCGCGACTCGCTGAACGCCGCGATCCTCGG
CACGGATATCGCCCCGACCGACCCGGAGTTCGATCTGTTCGTGCGGGAGGTGGCGCGTGAGATGACCAGCAAGGCCGGGC
AAAAATGCACCGCGATCCGCCGCGTGCTTGTGCCCCGCGCGCAGGAAGCCGCTGTCATCGCGGCCCTGCAGGCGACGCTG
ACCGACGTGAAGCTCGGCGATCCGCGCCAAGACGACAAGGCGATGGGCCCGCTGGTCAGCCGCGGCCAACGCGACACGGT
GCGCGCCGCGATCGCAGCGCTCGCCCCCGAGGCCGACATCGTGTTCGGAGACCCGCAGCGTTGCAGCGGCGACGGCATCG
ACACCACGGCGGGGGCTTACCTCTCGCCGATACTCCTGCGCGCAACGGACCCGATGCGCGCAGAGAAGCTCCACGCCATC
GAGGCGTTCGGACCCGTCGCGACCGTGATCGCCTATGACGACGTCGACCAGGTGATCGAGCTGGTTCGCCGCGGCGAAGG
CAGCCTGGTCGCGTCGCTGTTCACCTACGACAACGAGGTCGCCGAGCAGATCGCGCTCGGCATCGCGCCGTGGCACGGGC
GATTGCTGATCCTCGACCGCGATTGCGCCGCGGAATCCACCGGCCATGGCACGCCACTTCCGGCGTTGTTGCATGGAGGC
CCTGGCCGCGCCGGCGGCGGCGAAGAACTCGGCGGCCTGCGCAGCGTGCATCACTACATGCAGCGCACCGCAATCCAGTG
CTCGCCGCGCCGGCTGGCGGCATTGACCGGCACGTGGAGCCGCGGCGCACCGTCGCCGGTCTCGAATCTGCATCCGTTCA
AGCGCAACTTCGACGAACTGACCGTCGGCGAAAGCATCGAGACCGCGAGCCGGCCGATTACCCTCGACGACATCGAGCAC
TTCGCACATTTCACCGGCGACACGTTCTACGCCCATATGGACGAGGCGGCGGCCAAGGCCAACCCGTTCTTCCCCGGCCG
TGTCGCCCACGGCTATCTCATTCTGGCGTTCGCCGCCGGCCTGTTCGTCGACCCGGCACCGGGGCCGCTGTTGGCGAATT
ACGGCCTCGACAATCTGCGCTTCCTCAAGCCCGTCTCACCCGACGACACCATTCGCGTGAAGCTGACCGTGAAGCAGAAA
TCCTCCGCGCGGCGGCCGGAATACGGCGAGGTGCGGTGGGACGTCGAGGTGGTGAACCAGAACAACGAGCCGGTCGCGCG
CTACGACCTGCTGACGATGAGTGCCCGGCCGACATAG

Upstream 100 bases:

>100_bases
TCAGTCAATTATTAGCCCAAGCCACCATCGTGTCAACGGCCGCCGCGCACGTCAAACCGCGCGGCGCCGCGGGCCGAACA
AGAAAATCGGGGAGGACGCC

Downstream 100 bases:

>100_bases
CGGCATCCGGCACGCGCCATTCGGCGCGGCCGGCTCTCTACAAGTGATCGTAGTCCACCACCACCCGATCGGTGGTCGGT
TTCGCCTGGCAGGTCAGGAT

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MTTTLQSLARDAWVTPDTGLVDIPSAIDGRVVARASSAGLDFAAIVRHAREVGGPGLRALSFHQRADRLKAIGAYLIERK
EQLYAIAADTGANRRDNAIDIDGGLVTLAAYASRGRRELPDTKFIIEGEVEQFGKRGSFVGQHILSPLHGVAVHINAFNF
PCWGLLEKLAPALLAGVPVIAKPATATAYVAEALVKLIHESGLLPPGALQLICGSTGDLFDHLTGQDVIAFTGSIETSDK
LRAHPNVARHSIRFIAERDSLNAAILGTDIAPTDPEFDLFVREVAREMTSKAGQKCTAIRRVLVPRAQEAAVIAALQATL
TDVKLGDPRQDDKAMGPLVSRGQRDTVRAAIAALAPEADIVFGDPQRCSGDGIDTTAGAYLSPILLRATDPMRAEKLHAI
EAFGPVATVIAYDDVDQVIELVRRGEGSLVASLFTYDNEVAEQIALGIAPWHGRLLILDRDCAAESTGHGTPLPALLHGG
PGRAGGGEELGGLRSVHHYMQRTAIQCSPRRLAALTGTWSRGAPSPVSNLHPFKRNFDELTVGESIETASRPITLDDIEH
FAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILAFAAGLFVDPAPGPLLANYGLDNLRFLKPVSPDDTIRVKLTVKQK
SSARRPEYGEVRWDVEVVNQNNEPVARYDLLTMSARPT

Sequences:

>Translated_678_residues
MTTTLQSLARDAWVTPDTGLVDIPSAIDGRVVARASSAGLDFAAIVRHAREVGGPGLRALSFHQRADRLKAIGAYLIERK
EQLYAIAADTGANRRDNAIDIDGGLVTLAAYASRGRRELPDTKFIIEGEVEQFGKRGSFVGQHILSPLHGVAVHINAFNF
PCWGLLEKLAPALLAGVPVIAKPATATAYVAEALVKLIHESGLLPPGALQLICGSTGDLFDHLTGQDVIAFTGSIETSDK
LRAHPNVARHSIRFIAERDSLNAAILGTDIAPTDPEFDLFVREVAREMTSKAGQKCTAIRRVLVPRAQEAAVIAALQATL
TDVKLGDPRQDDKAMGPLVSRGQRDTVRAAIAALAPEADIVFGDPQRCSGDGIDTTAGAYLSPILLRATDPMRAEKLHAI
EAFGPVATVIAYDDVDQVIELVRRGEGSLVASLFTYDNEVAEQIALGIAPWHGRLLILDRDCAAESTGHGTPLPALLHGG
PGRAGGGEELGGLRSVHHYMQRTAIQCSPRRLAALTGTWSRGAPSPVSNLHPFKRNFDELTVGESIETASRPITLDDIEH
FAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILAFAAGLFVDPAPGPLLANYGLDNLRFLKPVSPDDTIRVKLTVKQK
SSARRPEYGEVRWDVEVVNQNNEPVARYDLLTMSARPT
>Mature_677_residues
TTTLQSLARDAWVTPDTGLVDIPSAIDGRVVARASSAGLDFAAIVRHAREVGGPGLRALSFHQRADRLKAIGAYLIERKE
QLYAIAADTGANRRDNAIDIDGGLVTLAAYASRGRRELPDTKFIIEGEVEQFGKRGSFVGQHILSPLHGVAVHINAFNFP
CWGLLEKLAPALLAGVPVIAKPATATAYVAEALVKLIHESGLLPPGALQLICGSTGDLFDHLTGQDVIAFTGSIETSDKL
RAHPNVARHSIRFIAERDSLNAAILGTDIAPTDPEFDLFVREVAREMTSKAGQKCTAIRRVLVPRAQEAAVIAALQATLT
DVKLGDPRQDDKAMGPLVSRGQRDTVRAAIAALAPEADIVFGDPQRCSGDGIDTTAGAYLSPILLRATDPMRAEKLHAIE
AFGPVATVIAYDDVDQVIELVRRGEGSLVASLFTYDNEVAEQIALGIAPWHGRLLILDRDCAAESTGHGTPLPALLHGGP
GRAGGGEELGGLRSVHHYMQRTAIQCSPRRLAALTGTWSRGAPSPVSNLHPFKRNFDELTVGESIETASRPITLDDIEHF
AHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILAFAAGLFVDPAPGPLLANYGLDNLRFLKPVSPDDTIRVKLTVKQKS
SARRPEYGEVRWDVEVVNQNNEPVARYDLLTMSARPT

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=489, Percent_Identity=24.7443762781186, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI25777724, Length=352, Percent_Identity=28.125, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI25777728, Length=352, Percent_Identity=28.4090909090909, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI153266822, Length=300, Percent_Identity=28, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI21361176, Length=469, Percent_Identity=25.7995735607676, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI25777730, Length=314, Percent_Identity=27.7070063694268, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI25777732, Length=452, Percent_Identity=25.6637168141593, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI73695881, Length=298, Percent_Identity=23.8255033557047, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI73695879, Length=298, Percent_Identity=23.8255033557047, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787653, Length=659, Percent_Identity=51.4415781487102, Blast_Score=603, Evalue=1e-174,
Organism=Escherichia coli, GI1787684, Length=501, Percent_Identity=24.750499001996, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787250, Length=352, Percent_Identity=26.7045454545455, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786504, Length=507, Percent_Identity=26.4299802761341, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789015, Length=438, Percent_Identity=25.5707762557078, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082295, Length=374, Percent_Identity=27.0053475935829, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787715, Length=346, Percent_Identity=26.0115606936416, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788042, Length=420, Percent_Identity=27.3809523809524, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081926, Length=445, Percent_Identity=23.8202247191011, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787558, Length=300, Percent_Identity=28, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87081896, Length=292, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25143874, Length=366, Percent_Identity=27.0491803278689, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25143876, Length=366, Percent_Identity=27.0491803278689, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562198, Length=353, Percent_Identity=27.7620396600567, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17551164, Length=382, Percent_Identity=25.6544502617801, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115532534, Length=312, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534176, Length=374, Percent_Identity=26.7379679144385, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI32564151, Length=318, Percent_Identity=27.9874213836478, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=312, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133930964, Length=349, Percent_Identity=26.0744985673352, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32564736, Length=308, Percent_Identity=26.6233766233766, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=308, Percent_Identity=26.6233766233766, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534119, Length=498, Percent_Identity=23.2931726907631, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324950, Length=308, Percent_Identity=25.3246753246753, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323822, Length=385, Percent_Identity=25.974025974026, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320917, Length=370, Percent_Identity=25.4054054054054, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323821, Length=314, Percent_Identity=26.7515923566879, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325196, Length=296, Percent_Identity=26.6891891891892, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362580, Length=352, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472918, Length=352, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472926, Length=352, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472936, Length=352, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356737, Length=352, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650465, Length=456, Percent_Identity=23.9035087719298, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 72833; Mature: 72701

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLQSLARDAWVTPDTGLVDIPSAIDGRVVARASSAGLDFAAIVRHAREVGGPGLRAL
CCCCHHHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHH
SFHQRADRLKAIGAYLIERKEQLYAIAADTGANRRDNAIDIDGGLVTLAAYASRGRRELP
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEECCCCHHHHHHHHHCCCCCCC
DTKFIIEGEVEQFGKRGSFVGQHILSPLHGVAVHINAFNFPCWGLLEKLAPALLAGVPVI
CCEEEEECCHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCE
AKPATATAYVAEALVKLIHESGLLPPGALQLICGSTGDLFDHLTGQDVIAFTGSIETSDK
ECCCHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCHHHHHCCCCCEEEEECCCCCCCH
LRAHPNVARHSIRFIAERDSLNAAILGTDIAPTDPEFDLFVREVAREMTSKAGQKCTAIR
HHCCCCHHHHHHHHEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHH
RVLVPRAQEAAVIAALQATLTDVKLGDPRQDDKAMGPLVSRGQRDTVRAAIAALAPEADI
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHCCCHHHHHHHHHHHCCCCCE
VFGDPQRCSGDGIDTTAGAYLSPILLRATDPMRAEKLHAIEAFGPVATVIAYDDVDQVIE
EECCCCCCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHH
LVRRGEGSLVASLFTYDNEVAEQIALGIAPWHGRLLILDRDCAAESTGHGTPLPALLHGG
HHHCCCCCEEEHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCHHEECC
PGRAGGGEELGGLRSVHHYMQRTAIQCSPRRLAALTGTWSRGAPSPVSNLHPFKRNFDEL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCHHHCCHHHCCCCCE
TVGESIETASRPITLDDIEHFAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILAFAAG
ECCCCHHHCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHEEHHHH
LFVDPAPGPLLANYGLDNLRFLKPVSPDDTIRVKLTVKQKSSARRPEYGEVRWDVEVVNQ
HEECCCCCCEEECCCCCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEECC
NNEPVARYDLLTMSARPT
CCCCEEEEEEEEECCCCC
>Mature Secondary Structure 
TTTLQSLARDAWVTPDTGLVDIPSAIDGRVVARASSAGLDFAAIVRHAREVGGPGLRAL
CCCHHHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCHHH
SFHQRADRLKAIGAYLIERKEQLYAIAADTGANRRDNAIDIDGGLVTLAAYASRGRRELP
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEECCCCHHHHHHHHHCCCCCCC
DTKFIIEGEVEQFGKRGSFVGQHILSPLHGVAVHINAFNFPCWGLLEKLAPALLAGVPVI
CCEEEEECCHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCE
AKPATATAYVAEALVKLIHESGLLPPGALQLICGSTGDLFDHLTGQDVIAFTGSIETSDK
ECCCHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCHHHHHCCCCCEEEEECCCCCCCH
LRAHPNVARHSIRFIAERDSLNAAILGTDIAPTDPEFDLFVREVAREMTSKAGQKCTAIR
HHCCCCHHHHHHHHEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHH
RVLVPRAQEAAVIAALQATLTDVKLGDPRQDDKAMGPLVSRGQRDTVRAAIAALAPEADI
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHCCCHHHHHHHHHHHCCCCCE
VFGDPQRCSGDGIDTTAGAYLSPILLRATDPMRAEKLHAIEAFGPVATVIAYDDVDQVIE
EECCCCCCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHH
LVRRGEGSLVASLFTYDNEVAEQIALGIAPWHGRLLILDRDCAAESTGHGTPLPALLHGG
HHHCCCCCEEEHHHHHCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCHHEECC
PGRAGGGEELGGLRSVHHYMQRTAIQCSPRRLAALTGTWSRGAPSPVSNLHPFKRNFDEL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCHHHCCHHHCCCCCE
TVGESIETASRPITLDDIEHFAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILAFAAG
ECCCCHHHCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHEEHHHH
LFVDPAPGPLLANYGLDNLRFLKPVSPDDTIRVKLTVKQKSSARRPEYGEVRWDVEVVNQ
HEECCCCCCEEECCCCCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEECC
NNEPVARYDLLTMSARPT
CCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]