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The map label for this gene is pcp [H]

Identifier: 86750653

GI number: 86750653

Start: 4053924

End: 4054583

Strand: Direct

Name: pcp [H]

Synonym: RPB_3543

Alternate gene names: 86750653

Gene position: 4053924-4054583 (Clockwise)

Preceding gene: 86750652

Following gene: 86750654

Centisome position: 76.03

GC content: 70.45

Gene sequence:

>660_bases
ATGAGCGCGCTGCGCATCCTGATCACCGGGTTCGGCCCGTTTCCCGGTGCGCCGTTCAATCCGACGCCGGCGCTGGTCGC
GCGGCTGATGAATTTGCGGCGGCCGGCGCTCGATGCGATCGAGCGCATCGGCCACGTGTTTCCGGTGAGCTATCGCGCGG
TGGATGCCGAACTGCCGGATCTCCTGGCGATGCATCGCCCCGACGCGCTACTGATGTTCGGCCTCGCCGCCCGCACGCGG
CATCTGCGGATCGAGACCCGCGCCCGCAATGCGATCACCACGCTGTGGCCGGACGCCGACCGGATCACGCTGCGCACCGC
CTCGATCGCGGCGGGCGAATCCGCGCGGGTGTTCGGACCACATTGCGAAAAGCTCGTCCGCGCCGCACGCGCCACCGGGA
TCGACGCAAGGGCCTCGCGCGACGCCGGCCGCTATCTGTGCAACTATCTGAGCTGGCGTGCGATCGAAGCCACGGCAACG
CCGCACGGCCCCCGCCTCGCCGCCTTCGTCCATGTGCCGCTGACGGCGCGCGATGGGCGGGCCTGGCCGGGCAGCGCGAT
CACCGCCGACCATCTGGTCGATGCCGGCGAGGCGATCCTGCTCGAACTGGTGAAACTGGCGCGCGGCAGACCGCGCCTCG
CTCGGCCTGATCCGGGTTAA

Upstream 100 bases:

>100_bases
ACCCCGCGATCCGCGCCAAGGTGAAGTCCACAGAAGCCGCCGTCGCCGAAGGCCGCGTCACGCCGGCGATCGGCGCCGAC
CAGATCGCGGAGCTCCTGGC

Downstream 100 bases:

>100_bases
CCCTATCGTCAAACATCGTCGCCCTGCGACACCGCCGCGACCGCGACGGCGGCGATTTCTGCGTTACTTCAAGCAGCGAG
TTCGCTCACCGAGGGATGCG

Product: peptidase C15, pyroglutamyl peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSALRILITGFGPFPGAPFNPTPALVARLMNLRRPALDAIERIGHVFPVSYRAVDAELPDLLAMHRPDALLMFGLAARTR
HLRIETRARNAITTLWPDADRITLRTASIAAGESARVFGPHCEKLVRAARATGIDARASRDAGRYLCNYLSWRAIEATAT
PHGPRLAAFVHVPLTARDGRAWPGSAITADHLVDAGEAILLELVKLARGRPRLARPDPG

Sequences:

>Translated_219_residues
MSALRILITGFGPFPGAPFNPTPALVARLMNLRRPALDAIERIGHVFPVSYRAVDAELPDLLAMHRPDALLMFGLAARTR
HLRIETRARNAITTLWPDADRITLRTASIAAGESARVFGPHCEKLVRAARATGIDARASRDAGRYLCNYLSWRAIEATAT
PHGPRLAAFVHVPLTARDGRAWPGSAITADHLVDAGEAILLELVKLARGRPRLARPDPG
>Mature_218_residues
SALRILITGFGPFPGAPFNPTPALVARLMNLRRPALDAIERIGHVFPVSYRAVDAELPDLLAMHRPDALLMFGLAARTRH
LRIETRARNAITTLWPDADRITLRTASIAAGESARVFGPHCEKLVRAARATGIDARASRDAGRYLCNYLSWRAIEATATP
HGPRLAAFVHVPLTARDGRAWPGSAITADHLVDAGEAILLELVKLARGRPRLARPDPG

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23808; Mature: 23677

Theoretical pI: Translated: 11.48; Mature: 11.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALRILITGFGPFPGAPFNPTPALVARLMNLRRPALDAIERIGHVFPVSYRAVDAELPD
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCHH
LLAMHRPDALLMFGLAARTRHLRIETRARNAITTLWPDADRITLRTASIAAGESARVFGP
HHHHCCCCHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCH
HCEKLVRAARATGIDARASRDAGRYLCNYLSWRAIEATATPHGPRLAAFVHVPLTARDGR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEEEEEECCCC
AWPGSAITADHLVDAGEAILLELVKLARGRPRLARPDPG
CCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SALRILITGFGPFPGAPFNPTPALVARLMNLRRPALDAIERIGHVFPVSYRAVDAELPD
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCHH
LLAMHRPDALLMFGLAARTRHLRIETRARNAITTLWPDADRITLRTASIAAGESARVFGP
HHHHCCCCHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCH
HCEKLVRAARATGIDARASRDAGRYLCNYLSWRAIEATATPHGPRLAAFVHVPLTARDGR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEEEEEECCCC
AWPGSAITADHLVDAGEAILLELVKLARGRPRLARPDPG
CCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]