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The map label for this gene is ybdL [H]

Identifier: 86750472

GI number: 86750472

Start: 3844041

End: 3845195

Strand: Reverse

Name: ybdL [H]

Synonym: RPB_3361

Alternate gene names: 86750472

Gene position: 3845195-3844041 (Counterclockwise)

Preceding gene: 86750473

Following gene: 86750471

Centisome position: 72.12

GC content: 65.19

Gene sequence:

>1155_bases
ATGAACAGGGTCTTCGCCGATCTGCCCGTCACCGTGTTCGAGGCGATGTCGCAGCTCGCACGCGACAACAACGCGATCAA
TCTCGGCCAGGGGTTTCCGGACGATCCGGGGCCGGAGGACATCCGCCGGGCCGCGGCCGACGCGGTGCTGAACGGCTACA
ACCAATATCCCTCGATGATGGGGATCCCGGAACTGCGGCAGGCGATCGCCACCCATTACGGGCATTGGCACGGCGTCGCG
CTCGACCCGATGACCGAGGTGATGGTGACCTCCGGCGCCACCGAGGCGCTGGCCAGCGCCATTCTCTCGGTGGTCTCGCC
GGGCGATGAAGTCATCGTGTTTCAGCCGGTGTACGATTCCTACCTGCCGATTATCCGGCAGGCGGGCGGCATTCCGCGCC
TGGTCCGGCTCGAGCCGCCGCACTGGCGGATCACCGAGGAGGCGTTGCGCCGGGTCTTCAACGCCAAGACCAAGGCGATC
GTCTTCAACAACCCGCTCAATCCCGCCGCGGTCGTCTATCCGCGCGAGGATCTCGAACTGTTGGCGCGGTTCTGCCAGGA
GTACGACGCCGTCGCCATCTGCGACGAGGTGTGGGAACACGTCACCTTCGATGGCCTCAGCCACATCCCGCTGATTGCGA
TCGAGGGCATGCGCGACCGCACGATCAAGATCGGCTCGGCCGGCAAGATCTTCTCTTTGACCGGCTGGAAGGTCGGTTTC
GTCTGCGCGGCGCCGCCGCTGTTGCGGGTGGCGGCCAAGGTGCATCAGTTCCTCGCCTTCACCACGGCGCCCAATCTGCA
GGTCGCGGTCGCCTACGGGCTCGGCAAATGCGACGACTACTTTTTGCAGATGCGCAAGGACCTGGCGCGAAGCCGCGACC
GGCTGGCGCGGGGCCTGTCGAGCATCGGCTTCCCGGTGATCCGGTCGCAGGGCACGTACTTCCTCACCGTCGATCTGTCG
CCGCTCGGCCTCAACGAGACCGACGAGGTGTTCTGCAAGCGGATCGTCAACGACTACAAGGTCGCCGCGATTCCGGTGTC
GGCATTCTACGAGGAGGAGCCGGTCACTTCGGTGGTGCGGTTCTGTTTCGCCAAACAGGATCAGACGCTCGACACCGCGC
TCGAGCGGCTGTCGGATGCGGTGCACAGGCGTTAG

Upstream 100 bases:

>100_bases
GCGCAGATGTCAGGGCTCGCCTACAACAAGCATCTCGCCGGCGGCATCCTCGGATGGAAGGCGGCAGGCCTGCCGACCAA
GCCGGGCGGCTGATCGCGCG

Downstream 100 bases:

>100_bases
GACTTCGATGATGCGGAACGATCTCCTTCGACGGCTGCGATTCGTCGGCGCGACGCTGGGGCTTTCGGCGAGCCTCGCCG
TGCCGGCGCTGGCGCAGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNRVFADLPVTVFEAMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMMGIPELRQAIATHYGHWHGVA
LDPMTEVMVTSGATEALASAILSVVSPGDEVIVFQPVYDSYLPIIRQAGGIPRLVRLEPPHWRITEEALRRVFNAKTKAI
VFNNPLNPAAVVYPREDLELLARFCQEYDAVAICDEVWEHVTFDGLSHIPLIAIEGMRDRTIKIGSAGKIFSLTGWKVGF
VCAAPPLLRVAAKVHQFLAFTTAPNLQVAVAYGLGKCDDYFLQMRKDLARSRDRLARGLSSIGFPVIRSQGTYFLTVDLS
PLGLNETDEVFCKRIVNDYKVAAIPVSAFYEEEPVTSVVRFCFAKQDQTLDTALERLSDAVHRR

Sequences:

>Translated_384_residues
MNRVFADLPVTVFEAMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMMGIPELRQAIATHYGHWHGVA
LDPMTEVMVTSGATEALASAILSVVSPGDEVIVFQPVYDSYLPIIRQAGGIPRLVRLEPPHWRITEEALRRVFNAKTKAI
VFNNPLNPAAVVYPREDLELLARFCQEYDAVAICDEVWEHVTFDGLSHIPLIAIEGMRDRTIKIGSAGKIFSLTGWKVGF
VCAAPPLLRVAAKVHQFLAFTTAPNLQVAVAYGLGKCDDYFLQMRKDLARSRDRLARGLSSIGFPVIRSQGTYFLTVDLS
PLGLNETDEVFCKRIVNDYKVAAIPVSAFYEEEPVTSVVRFCFAKQDQTLDTALERLSDAVHRR
>Mature_384_residues
MNRVFADLPVTVFEAMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMMGIPELRQAIATHYGHWHGVA
LDPMTEVMVTSGATEALASAILSVVSPGDEVIVFQPVYDSYLPIIRQAGGIPRLVRLEPPHWRITEEALRRVFNAKTKAI
VFNNPLNPAAVVYPREDLELLARFCQEYDAVAICDEVWEHVTFDGLSHIPLIAIEGMRDRTIKIGSAGKIFSLTGWKVGF
VCAAPPLLRVAAKVHQFLAFTTAPNLQVAVAYGLGKCDDYFLQMRKDLARSRDRLARGLSSIGFPVIRSQGTYFLTVDLS
PLGLNETDEVFCKRIVNDYKVAAIPVSAFYEEEPVTSVVRFCFAKQDQTLDTALERLSDAVHRR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=393, Percent_Identity=37.1501272264631, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI169881279, Length=393, Percent_Identity=37.1501272264631, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=37.27959697733, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=37.27959697733, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=32.3155216284987, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI4507369, Length=330, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=37.9032258064516, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1788722, Length=351, Percent_Identity=26.4957264957265, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788627, Length=192, Percent_Identity=22.9166666666667, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=400, Percent_Identity=34.25, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71994476, Length=401, Percent_Identity=34.1645885286783, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=30.1507537688442, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17567663, Length=354, Percent_Identity=22.316384180791, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=384, Percent_Identity=32.8125, Blast_Score=189, Evalue=6e-49,
Organism=Drosophila melanogaster, GI28573069, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24646114, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI28573067, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI28573065, Length=399, Percent_Identity=36.8421052631579, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI18859735, Length=350, Percent_Identity=25.1428571428571, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42567; Mature: 42567

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVFADLPVTVFEAMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMM
CCCEECCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GIPELRQAIATHYGHWHGVALDPMTEVMVTSGATEALASAILSVVSPGDEVIVFQPVYDS
CCHHHHHHHHHHCCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCHHH
YLPIIRQAGGIPRLVRLEPPHWRITEEALRRVFNAKTKAIVFNNPLNPAAVVYPREDLEL
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEECHHHHHH
LARFCQEYDAVAICDEVWEHVTFDGLSHIPLIAIEGMRDRTIKIGSAGKIFSLTGWKVGF
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCEEEECCCEEEE
VCAAPPLLRVAAKVHQFLAFTTAPNLQVAVAYGLGKCDDYFLQMRKDLARSRDRLARGLS
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SIGFPVIRSQGTYFLTVDLSPLGLNETDEVFCKRIVNDYKVAAIPVSAFYEEEPVTSVVR
HCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHH
FCFAKQDQTLDTALERLSDAVHRR
HHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRVFADLPVTVFEAMSQLARDNNAINLGQGFPDDPGPEDIRRAAADAVLNGYNQYPSMM
CCCEECCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GIPELRQAIATHYGHWHGVALDPMTEVMVTSGATEALASAILSVVSPGDEVIVFQPVYDS
CCHHHHHHHHHHCCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCHHH
YLPIIRQAGGIPRLVRLEPPHWRITEEALRRVFNAKTKAIVFNNPLNPAAVVYPREDLEL
HHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEECHHHHHH
LARFCQEYDAVAICDEVWEHVTFDGLSHIPLIAIEGMRDRTIKIGSAGKIFSLTGWKVGF
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCEEEECCCEEEE
VCAAPPLLRVAAKVHQFLAFTTAPNLQVAVAYGLGKCDDYFLQMRKDLARSRDRLARGLS
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SIGFPVIRSQGTYFLTVDLSPLGLNETDEVFCKRIVNDYKVAAIPVSAFYEEEPVTSVVR
HCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHH
FCFAKQDQTLDTALERLSDAVHRR
HHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]