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The map label for this gene is siaT [H]

Identifier: 86750438

GI number: 86750438

Start: 3806304

End: 3807596

Strand: Reverse

Name: siaT [H]

Synonym: RPB_3327

Alternate gene names: 86750438

Gene position: 3807596-3806304 (Counterclockwise)

Preceding gene: 86750439

Following gene: 86750437

Centisome position: 71.41

GC content: 63.5

Gene sequence:

>1293_bases
ATGAACACCATCTTCCTGTTCGCGACGCTGTTCGCGTTGCTCGGCATCGGCATGCCGATCGCGATGTCGCTCGGCCTGTC
GTCGATCCTGACGATCCTGCTGTTCCAGAACGACAGCCTGGCCTCGCTGGTGCTGAAGTTCTTCCAGACCACCGAGCAGT
TCACGCTGCTGGCGATTCCGTTCTTCATTCTGGCCGGCAATTTTCTCACCACCGGTGGCGTCGCCAAGCGGATGATCAAT
TTCGCGATCGCCGCGGTCGGCCATCTGCCGGGCGGCCTCGCGATCGCCTCGGTGCTGGCCTGCATGCTGTTCGCCGCGGT
GTCGGGTTCGTCGCCGGCCACCGTGGTCGCGATCGGTTCGATCGTGATCGCCGGCATGGTCAAGGTCGGTTACACTCAGG
CCTTCGCCACCGGCGTGATCGTCAATGCCGGCACCCTCGGCATTCTGATCCCGCCTTCGATCGTCATGGTGGTGTTCGCC
GCGGCCACCGAATCGTCGGTCGGGCGGCTGTTCATCGCCGGCATCATTCCCGGCCTGCTGCTCGGCCTCGCGCTGATGGT
GGCGATCTATGTCACGGCGCGGATCAAGAAGCTGCCGCGGCAGCCGAAGGCGTCCTGGGGCGAGCGGCTGTCGCTGTTCG
GCCAGGCCTCGTGGGGGCTGTTGCTGATCCTGATCGTGATGGGCGGCATCTATGGCGGCATCTTCACGCCGACCGAGGCG
GCCGCCGTGGCCGCGGTCTATGCCTTCGTCGCCGCGGTGTTCATCTATCGCGACCTCAAGATCGTCGAGGTGCCGCGGGT
GCTGCTGGATTCCGGGCGGGTCTCGGTGATGCTGATGTTCATCATCTGCAATGCCTTCCTGTTCGCCCACGTCCTGACCA
CGGCGCAGATTCCGCAGGACATCGCCCGGCTGATCACCGACGCGCAGTTGCAGCCCTGGCACTTCCTGCTGATCGTCAAC
ATCATCCTGCTGGTCGCCGGCAATTTCATGGATCCGACCGCGATCGTGCTGATCACCGCGCCGATCCTGTTCCCGACCGC
GATGCAACTCGGCATCGATCCGATTCATCTCGGTATCATCTATGTGGTGAACATGGAGATCGGGCTGGTGACGCCACCTG
TCGGGCTCAACCTGTTCGTCGCCTCGGGTATTACCGGCATGCCACTCACCAAGGTGGTGCGCGCGGCGGCGCCCTGGCTG
CTGGTGCTGCTCGCTTTCCTGGTTCTCATCACCTATGTGCCGGTGATCTCCACCTTCCTGCCCAATCTCGTGTTCGGTCC
GGCACTCAAGTAG

Upstream 100 bases:

>100_bases
CCGGCCAGTCCGGCGGCTACGAATTGGCCGACGAGGCCCGCGAGGCGGTGGAACATCACCTGCCGAATCACCCGGAACCC
GACGCCACGACGGTGCAGCG

Downstream 100 bases:

>100_bases
CCGGGTGACAGAATGTTGCGATTGTTGCAGAACGCGGTCGATGTGTTTCCGGCAGATTACATCTTGGTCATCAGCGGCAT
TCTGTCGAAACCGTAAGTTG

Product: TRAP dicarboxylate transporter DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MNTIFLFATLFALLGIGMPIAMSLGLSSILTILLFQNDSLASLVLKFFQTTEQFTLLAIPFFILAGNFLTTGGVAKRMIN
FAIAAVGHLPGGLAIASVLACMLFAAVSGSSPATVVAIGSIVIAGMVKVGYTQAFATGVIVNAGTLGILIPPSIVMVVFA
AATESSVGRLFIAGIIPGLLLGLALMVAIYVTARIKKLPRQPKASWGERLSLFGQASWGLLLILIVMGGIYGGIFTPTEA
AAVAAVYAFVAAVFIYRDLKIVEVPRVLLDSGRVSVMLMFIICNAFLFAHVLTTAQIPQDIARLITDAQLQPWHFLLIVN
IILLVAGNFMDPTAIVLITAPILFPTAMQLGIDPIHLGIIYVVNMEIGLVTPPVGLNLFVASGITGMPLTKVVRAAAPWL
LVLLAFLVLITYVPVISTFLPNLVFGPALK

Sequences:

>Translated_430_residues
MNTIFLFATLFALLGIGMPIAMSLGLSSILTILLFQNDSLASLVLKFFQTTEQFTLLAIPFFILAGNFLTTGGVAKRMIN
FAIAAVGHLPGGLAIASVLACMLFAAVSGSSPATVVAIGSIVIAGMVKVGYTQAFATGVIVNAGTLGILIPPSIVMVVFA
AATESSVGRLFIAGIIPGLLLGLALMVAIYVTARIKKLPRQPKASWGERLSLFGQASWGLLLILIVMGGIYGGIFTPTEA
AAVAAVYAFVAAVFIYRDLKIVEVPRVLLDSGRVSVMLMFIICNAFLFAHVLTTAQIPQDIARLITDAQLQPWHFLLIVN
IILLVAGNFMDPTAIVLITAPILFPTAMQLGIDPIHLGIIYVVNMEIGLVTPPVGLNLFVASGITGMPLTKVVRAAAPWL
LVLLAFLVLITYVPVISTFLPNLVFGPALK
>Mature_430_residues
MNTIFLFATLFALLGIGMPIAMSLGLSSILTILLFQNDSLASLVLKFFQTTEQFTLLAIPFFILAGNFLTTGGVAKRMIN
FAIAAVGHLPGGLAIASVLACMLFAAVSGSSPATVVAIGSIVIAGMVKVGYTQAFATGVIVNAGTLGILIPPSIVMVVFA
AATESSVGRLFIAGIIPGLLLGLALMVAIYVTARIKKLPRQPKASWGERLSLFGQASWGLLLILIVMGGIYGGIFTPTEA
AAVAAVYAFVAAVFIYRDLKIVEVPRVLLDSGRVSVMLMFIICNAFLFAHVLTTAQIPQDIARLITDAQLQPWHFLLIVN
IILLVAGNFMDPTAIVLITAPILFPTAMQLGIDPIHLGIIYVVNMEIGLVTPPVGLNLFVASGITGMPLTKVVRAAAPWL
LVLLAFLVLITYVPVISTFLPNLVFGPALK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=398, Percent_Identity=34.9246231155779, Blast_Score=227, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45403; Mature: 45403

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIFLFATLFALLGIGMPIAMSLGLSSILTILLFQNDSLASLVLKFFQTTEQFTLLAIP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
FFILAGNFLTTGGVAKRMINFAIAAVGHLPGGLAIASVLACMLFAAVSGSSPATVVAIGS
HHHHHCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IVIAGMVKVGYTQAFATGVIVNAGTLGILIPPSIVMVVFAAATESSVGRLFIAGIIPGLL
HHHHHHHHHHHHHHHHHHEEEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LGLALMVAIYVTARIKKLPRQPKASWGERLSLFGQASWGLLLILIVMGGIYGGIFTPTEA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
AAVAAVYAFVAAVFIYRDLKIVEVPRVLLDSGRVSVMLMFIICNAFLFAHVLTTAQIPQD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARLITDAQLQPWHFLLIVNIILLVAGNFMDPTAIVLITAPILFPTAMQLGIDPIHLGII
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEE
YVVNMEIGLVTPPVGLNLFVASGITGMPLTKVVRAAAPWLLVLLAFLVLITYVPVISTFL
EEEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
PNLVFGPALK
HHHHCCCCCC
>Mature Secondary Structure
MNTIFLFATLFALLGIGMPIAMSLGLSSILTILLFQNDSLASLVLKFFQTTEQFTLLAIP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
FFILAGNFLTTGGVAKRMINFAIAAVGHLPGGLAIASVLACMLFAAVSGSSPATVVAIGS
HHHHHCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IVIAGMVKVGYTQAFATGVIVNAGTLGILIPPSIVMVVFAAATESSVGRLFIAGIIPGLL
HHHHHHHHHHHHHHHHHHEEEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LGLALMVAIYVTARIKKLPRQPKASWGERLSLFGQASWGLLLILIVMGGIYGGIFTPTEA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHH
AAVAAVYAFVAAVFIYRDLKIVEVPRVLLDSGRVSVMLMFIICNAFLFAHVLTTAQIPQD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARLITDAQLQPWHFLLIVNIILLVAGNFMDPTAIVLITAPILFPTAMQLGIDPIHLGII
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEE
YVVNMEIGLVTPPVGLNLFVASGITGMPLTKVVRAAAPWLLVLLAFLVLITYVPVISTFL
EEEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
PNLVFGPALK
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]