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The map label for this gene is rhlI [H]

Identifier: 86750431

GI number: 86750431

Start: 3798800

End: 3799432

Strand: Reverse

Name: rhlI [H]

Synonym: RPB_3320

Alternate gene names: 86750431

Gene position: 3799432-3798800 (Counterclockwise)

Preceding gene: 86750432

Following gene: 86750415

Centisome position: 71.26

GC content: 59.08

Gene sequence:

>633_bases
ATGATCCACCTCGTCACAGCAGAAAATGCTGCTGCGTATCACGAATTGATGGAGCAAGCGTTCCGGCTACGGCATGCGGT
GTTTGTCGACGAATTGGGCTGGCACGACCTAAAGCGCGAAGATGGACGTGACGTCGATCAATTCGACGACGGCCGCGCGC
TGCATATGCTGTACGTCGAGAACGGTCGCGTGCTCGGCTATCAACGTATGTTGCCTTCACTTCGCCCGCACCTGCTATCG
GACGTACTGCGGCATTTGTGCGATGGCGATCTTCCGGTCGGGCCGCAGATTTGGGAATGGACACGCTATTGCGTCGCACC
AGGCTGCCGGGATCGTGGCCGAATGCTGAGTCCGGTTGGCAACATGCTACTATCGGCGATTGTCGAGTGGGGTCTCGAAA
GCGGCGTTTCCGAGATCATCATCGAAATGAATCCGATCTGGCTGCTGCGGCTGGTGCAGCTCCACTTCAGGGTGACGCCG
CTTGGCATCCCGCAGAAGGTCGGGAAAGACGACGTCGTCGCCGTGACGGCCGCATTCGATCGTAGGACGCTGAATCGCCT
TCGCGAAATGCGAGGTGACGAGCGAGAGGTGATTGTGTCGCGCCCGATATCGACTAGGCGGCTGCTCGCCTGA

Upstream 100 bases:

>100_bases
GGGATAATTCGTTGATTTGTCAAGGTACGGAAAGCCGTACTAGCTGAATCAGGAGCTTCACCAGATCATCTCCCCGCACA
AATCAGAAGGGGAGAGTGCA

Downstream 100 bases:

>100_bases
CCGATGCCTAAGATCTGTAGTCAGTTCGATTTCTCAGCTTGACGGTCGACCGCATCCTGAGCAGCGGCAATGATCTTCAG
CCGCTCCTCGCGATCCGTAA

Product: autoinducer synthesis protein

Products: NA

Alternate protein names: Autoinducer synthesis protein rhlI [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIHLVTAENAAAYHELMEQAFRLRHAVFVDELGWHDLKREDGRDVDQFDDGRALHMLYVENGRVLGYQRMLPSLRPHLLS
DVLRHLCDGDLPVGPQIWEWTRYCVAPGCRDRGRMLSPVGNMLLSAIVEWGLESGVSEIIIEMNPIWLLRLVQLHFRVTP
LGIPQKVGKDDVVAVTAAFDRRTLNRLREMRGDEREVIVSRPISTRRLLA

Sequences:

>Translated_210_residues
MIHLVTAENAAAYHELMEQAFRLRHAVFVDELGWHDLKREDGRDVDQFDDGRALHMLYVENGRVLGYQRMLPSLRPHLLS
DVLRHLCDGDLPVGPQIWEWTRYCVAPGCRDRGRMLSPVGNMLLSAIVEWGLESGVSEIIIEMNPIWLLRLVQLHFRVTP
LGIPQKVGKDDVVAVTAAFDRRTLNRLREMRGDEREVIVSRPISTRRLLA
>Mature_210_residues
MIHLVTAENAAAYHELMEQAFRLRHAVFVDELGWHDLKREDGRDVDQFDDGRALHMLYVENGRVLGYQRMLPSLRPHLLS
DVLRHLCDGDLPVGPQIWEWTRYCVAPGCRDRGRMLSPVGNMLLSAIVEWGLESGVSEIIIEMNPIWLLRLVQLHFRVTP
LGIPQKVGKDDVVAVTAAFDRRTLNRLREMRGDEREVIVSRPISTRRLLA

Specific function: Required for the synthesis of BHL (N-butanoyl-L- homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone) autoinducer molecules which bind to rhlR and thus acts in elastase biosynthesis regulation [H]

COG id: COG3916

COG function: function code TQ; N-acyl-L-homoserine lactone synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autoinducer synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR001690
- InterPro:   IPR018311 [H]

Pfam domain/function: PF00765 Autoind_synth [H]

EC number: =2.3.1.184 [H]

Molecular weight: Translated: 24137; Mature: 24137

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHLVTAENAAAYHELMEQAFRLRHAVFVDELGWHDLKREDGRDVDQFDDGRALHMLYVE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEEEEE
NGRVLGYQRMLPSLRPHLLSDVLRHLCDGDLPVGPQIWEWTRYCVAPGCRDRGRMLSPVG
CCCEECHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
NMLLSAIVEWGLESGVSEIIIEMNPIWLLRLVQLHFRVTPLGIPQKVGKDDVVAVTAAFD
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEHHHH
RRTLNRLREMRGDEREVIVSRPISTRRLLA
HHHHHHHHHHCCCCCEEEEECCCCHHHCCC
>Mature Secondary Structure
MIHLVTAENAAAYHELMEQAFRLRHAVFVDELGWHDLKREDGRDVDQFDDGRALHMLYVE
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEEEEEEE
NGRVLGYQRMLPSLRPHLLSDVLRHLCDGDLPVGPQIWEWTRYCVAPGCRDRGRMLSPVG
CCCEECHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
NMLLSAIVEWGLESGVSEIIIEMNPIWLLRLVQLHFRVTPLGIPQKVGKDDVVAVTAAFD
HHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEHHHH
RRTLNRLREMRGDEREVIVSRPISTRRLLA
HHHHHHHHHHCCCCCEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7604006; 8522523; 7494482; 10984043 [H]