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The map label for this gene is yngJ [H]

Identifier: 86750377

GI number: 86750377

Start: 3736385

End: 3737542

Strand: Reverse

Name: yngJ [H]

Synonym: RPB_3266

Alternate gene names: 86750377

Gene position: 3737542-3736385 (Counterclockwise)

Preceding gene: 86750378

Following gene: 86750376

Centisome position: 70.1

GC content: 64.42

Gene sequence:

>1158_bases
ATGCTGTTCAATGCCGACCATGACGAGCCGCGCCGCGTGCTGCAGAAATTCATCGCCAGCGACATCAATCCGCATGTCGA
CGAATGGGAGAAGGCCGGCATCTTCCCGGCGCACGAGCTGTTCAAGAAGCTCGGCGATCTCGGTTTTCTCGGGCTCAACA
AGCCGGTCGAATACGGCGGGCAGGGGCTGGATTATTCCTACGCGCTGATGATGGCGGAGGAACTCGGCAACATCAATTGC
GGCGGCGTGCCGATGGCGATCGGCGTGCAGACCGACATGGCGACGCCGGCGCTGGCGAAGTTCGGCTCCGACGAATTGCG
CAAGGAATTTCTCGCGCCGTCGATCAGCGGAGATTTCGTCGCCTGCATCGGCGTGTCCGAGCCCGGCGCCGGCTCCGACG
TCGCCTCGATCAAGACCACCGCGAAATCCGACGGCGACGACTACGTCATTAGCGGCGGCAAGATGTGGATCACCAACGGC
ACCCAGGCCGACTGGATCTGCCTGCTGTGCAACACCGGCGACGGGCCGGCGCATCGCAACAAGTCGCTGATCTGCGTGCC
GATGAAGAGCAAGGGCGTCAGCATCGCGCGCAAGCTCGACAAGATGGGGATGCACTCGTCCGACACCGCGCAGATCCATT
TCGACGAGGTGCGGGTGCCGAAGCGCAACCGGATCGGCGAAGAGGGAGCGGGGTTCACCTATCAGATGGTGCAGTTCCAG
GAAGAGCGGCTGTGGGGCGCCGCGGCGTGCATCAAGGCGCACGAGAGGACGATCCAGAACACCATCGACTACACCCGCGA
CCGCAAGGCGTTCGGCCGGCCGCTGCTGGACAATCAGGTGATTCACTTCAAGCTCGCGGAGCTGCAGACCGAGGTCGAAT
TGCTGCGCTCGCTGGTGTATCGCGCCGCCGAAGCGCTGGTCGCCGGCGAGGACGTCACCCAGCTCGCCACCATGGCCAAA
CTGCGCGCCGGCCGGCTCGGCCGCGAACTGCCGGATGCCTGCCTGCAATATTGGGGCGGGATGGGCTTCATGAACGAGAC
GCTGGTCAGCCGCTCCTACCGGGATTCCCGCCTGACCTCGATCGGCGGCGGCGCCGACGAGGTGATGCTCGGAATCCTGT
GCAAGATGATGGGCACGCTGCCGGGCGGCAAGAAGTAG

Upstream 100 bases:

>100_bases
AAGCGACGAAGCAATCCAGGTCGGTGCACTGAGCTGGATTGCTTCGCTTCGCTCGCAATGACGGGGACAGGGTTACGATA
ATAAGAAGGTAGACGCCTCG

Downstream 100 bases:

>100_bases
ACCCAGCCGTCCAGCGTATGGACGCAAGATAGCGTGCGCGACTGTCCCCTACGCTGCTACCTGATAACTGCGCGCAAGAC
GCAGACAGTTCCAGCACAAC

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MLFNADHDEPRRVLQKFIASDINPHVDEWEKAGIFPAHELFKKLGDLGFLGLNKPVEYGGQGLDYSYALMMAEELGNINC
GGVPMAIGVQTDMATPALAKFGSDELRKEFLAPSISGDFVACIGVSEPGAGSDVASIKTTAKSDGDDYVISGGKMWITNG
TQADWICLLCNTGDGPAHRNKSLICVPMKSKGVSIARKLDKMGMHSSDTAQIHFDEVRVPKRNRIGEEGAGFTYQMVQFQ
EERLWGAAACIKAHERTIQNTIDYTRDRKAFGRPLLDNQVIHFKLAELQTEVELLRSLVYRAAEALVAGEDVTQLATMAK
LRAGRLGRELPDACLQYWGGMGFMNETLVSRSYRDSRLTSIGGGADEVMLGILCKMMGTLPGGKK

Sequences:

>Translated_385_residues
MLFNADHDEPRRVLQKFIASDINPHVDEWEKAGIFPAHELFKKLGDLGFLGLNKPVEYGGQGLDYSYALMMAEELGNINC
GGVPMAIGVQTDMATPALAKFGSDELRKEFLAPSISGDFVACIGVSEPGAGSDVASIKTTAKSDGDDYVISGGKMWITNG
TQADWICLLCNTGDGPAHRNKSLICVPMKSKGVSIARKLDKMGMHSSDTAQIHFDEVRVPKRNRIGEEGAGFTYQMVQFQ
EERLWGAAACIKAHERTIQNTIDYTRDRKAFGRPLLDNQVIHFKLAELQTEVELLRSLVYRAAEALVAGEDVTQLATMAK
LRAGRLGRELPDACLQYWGGMGFMNETLVSRSYRDSRLTSIGGGADEVMLGILCKMMGTLPGGKK
>Mature_385_residues
MLFNADHDEPRRVLQKFIASDINPHVDEWEKAGIFPAHELFKKLGDLGFLGLNKPVEYGGQGLDYSYALMMAEELGNINC
GGVPMAIGVQTDMATPALAKFGSDELRKEFLAPSISGDFVACIGVSEPGAGSDVASIKTTAKSDGDDYVISGGKMWITNG
TQADWICLLCNTGDGPAHRNKSLICVPMKSKGVSIARKLDKMGMHSSDTAQIHFDEVRVPKRNRIGEEGAGFTYQMVQFQ
EERLWGAAACIKAHERTIQNTIDYTRDRKAFGRPLLDNQVIHFKLAELQTEVELLRSLVYRAAEALVAGEDVTQLATMAK
LRAGRLGRELPDACLQYWGGMGFMNETLVSRSYRDSRLTSIGGGADEVMLGILCKMMGTLPGGKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=35.2785145888594, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI4557233, Length=363, Percent_Identity=34.1597796143251, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=34.5744680851064, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=34.5744680851064, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=30.6233062330623, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI226958414, Length=333, Percent_Identity=32.1321321321321, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI7656849, Length=370, Percent_Identity=32.7027027027027, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=28.804347826087, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI76496475, Length=351, Percent_Identity=30.4843304843305, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI4557235, Length=351, Percent_Identity=30.4843304843305, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=27.3224043715847, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI38505218, Length=364, Percent_Identity=27.7472527472527, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=28.0276816608997, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=28.0276816608997, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI7669494, Length=287, Percent_Identity=28.2229965156794, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503943, Length=287, Percent_Identity=28.2229965156794, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI87081958, Length=346, Percent_Identity=31.5028901734104, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786223, Length=384, Percent_Identity=26.5625, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=52.1276595744681, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=52.6595744680851, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=33.3333333333333, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=32.8042328042328, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=31.758530183727, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=32.3287671232877, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=361, Percent_Identity=31.5789473684211, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=29.287598944591, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=30.327868852459, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=276, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=379, Percent_Identity=31.6622691292876, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=34.6153846153846, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=264, Percent_Identity=29.9242424242424, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=307, Percent_Identity=30.2931596091205, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=29.757785467128, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=26.5560165975104, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=24.4623655913978, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356377, Length=366, Percent_Identity=32.5136612021858, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24646207, Length=366, Percent_Identity=33.3333333333333, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24660351, Length=375, Percent_Identity=32.8, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21355753, Length=369, Percent_Identity=31.9783197831978, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=29.1891891891892, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281363737, Length=334, Percent_Identity=26.9461077844311, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19920834, Length=286, Percent_Identity=29.7202797202797, Blast_Score=118, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42076; Mature: 42076

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNADHDEPRRVLQKFIASDINPHVDEWEKAGIFPAHELFKKLGDLGFLGLNKPVEYGG
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHCCCCEECCCCCHHHCC
QGLDYSYALMMAEELGNINCGGVPMAIGVQTDMATPALAKFGSDELRKEFLAPSISGDFV
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCCCCCCEE
ACIGVSEPGAGSDVASIKTTAKSDGDDYVISGGKMWITNGTQADWICLLCNTGDGPAHRN
EEEECCCCCCCCCHHHHHHHCCCCCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCC
KSLICVPMKSKGVSIARKLDKMGMHSSDTAQIHFDEVRVPKRNRIGEEGAGFTYQMVQFQ
CCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHCCCCCCCCCCHHHHHHH
EERLWGAAACIKAHERTIQNTIDYTRDRKAFGRPLLDNQVIHFKLAELQTEVELLRSLVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
RAAEALVAGEDVTQLATMAKLRAGRLGRELPDACLQYWGGMGFMNETLVSRSYRDSRLTS
HHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
IGGGADEVMLGILCKMMGTLPGGKK
CCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLFNADHDEPRRVLQKFIASDINPHVDEWEKAGIFPAHELFKKLGDLGFLGLNKPVEYGG
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHCCCCEECCCCCHHHCC
QGLDYSYALMMAEELGNINCGGVPMAIGVQTDMATPALAKFGSDELRKEFLAPSISGDFV
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCCCCCCEE
ACIGVSEPGAGSDVASIKTTAKSDGDDYVISGGKMWITNGTQADWICLLCNTGDGPAHRN
EEEECCCCCCCCCHHHHHHHCCCCCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCC
KSLICVPMKSKGVSIARKLDKMGMHSSDTAQIHFDEVRVPKRNRIGEEGAGFTYQMVQFQ
CCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHCCCCCCCCCCHHHHHHH
EERLWGAAACIKAHERTIQNTIDYTRDRKAFGRPLLDNQVIHFKLAELQTEVELLRSLVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
RAAEALVAGEDVTQLATMAKLRAGRLGRELPDACLQYWGGMGFMNETLVSRSYRDSRLTS
HHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
IGGGADEVMLGILCKMMGTLPGGKK
CCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]