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The map label for this gene is cobK [H]

Identifier: 86750292

GI number: 86750292

Start: 3638572

End: 3639351

Strand: Reverse

Name: cobK [H]

Synonym: RPB_3181

Alternate gene names: 86750292

Gene position: 3639351-3638572 (Counterclockwise)

Preceding gene: 86750298

Following gene: 86750285

Centisome position: 68.26

GC content: 70.26

Gene sequence:

>780_bases
ATGCTCCATCCCGCCCAGCGCCTGCGCCTGTTGATCCTCGGCGGCACCGCCGATGCGACGCGACTCGCGACGGCGATCGC
CGCGGAGCCGCGCATCGAGGCCGTACTGTCGTTTGCCGGTCGCACCGACAATCCCAAGCCGCCGCCGATCCCTTGGCGGG
TCGGCGGCTTCGGCGGCGTACAGGGGTTGATCGATTACTTGCGCGCGGAGGGGATTGATCGCGTCGTCGATGCCACGCAT
CCGTTCGCGGCGCAGATGAGCCGCCACGCGGTCCAGGCCTGCGCCGCAGCCGGCGTGCCGCTGCTCGCACTCGAGCGCGC
GCCATGGCAGGCGGGTGAGGGCGATCGCTGGATCGAGGTCGACGATCTGGCGGCGGCAGCGCTGGCGCTCGGCGCGGCGC
CGCGCCGGGTGTTTCTCGGCATCGGCCGGCAGCATCTCGAATTGTTCGCCGCATATCCGCAGCACGCTTATCTGGTGCGA
CTGGTCGATCCGCCGCGTGCGGCGCTGCCGTTTCCACAGGTCGAAATCGTGATCGCGCGCGGGCCGTTCGACCGCGCCAG
TGATCGCGCACTGCTCGAAGCGCATCGCAGCGAGATGGTCGTCGCCAAGAATGCCGGTGGGGATGCAGCGGTAGCCAAGA
TCGAGGCGGCGCGCGATCTCGGGCTGCCGGTGGTGATGGTCCGGCGTCCGATTGTGCCGGCGCGGCTCGCGGTCGCCACG
GTCGCCGAGGTGATGGCGTGGCTCGGTCATGACGGCGCCTTCAGCGAGCGTGGCGTATAG

Upstream 100 bases:

>100_bases
CAGTAGCGCGCGTGCTTTGTCCGACAGGCCCGCGACGCCATCCTCGCCGATTCCGACGATGGACAGCCACGGCGTCGGCG
TGTCATCGGTGGCGGTCATG

Downstream 100 bases:

>100_bases
ACATAGCTGCCGCCGTCGGCGCGGGGGATGAGCCGCGTCTGCGACGATCCGATCATCACCACGGTGCGCATGTCCGCACG
GCTCGGAAGCGCATCGCCGA

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLHPAQRLRLLILGGTADATRLATAIAAEPRIEAVLSFAGRTDNPKPPPIPWRVGGFGGVQGLIDYLRAEGIDRVVDATH
PFAAQMSRHAVQACAAAGVPLLALERAPWQAGEGDRWIEVDDLAAAALALGAAPRRVFLGIGRQHLELFAAYPQHAYLVR
LVDPPRAALPFPQVEIVIARGPFDRASDRALLEAHRSEMVVAKNAGGDAAVAKIEAARDLGLPVVMVRRPIVPARLAVAT
VAEVMAWLGHDGAFSERGV

Sequences:

>Translated_259_residues
MLHPAQRLRLLILGGTADATRLATAIAAEPRIEAVLSFAGRTDNPKPPPIPWRVGGFGGVQGLIDYLRAEGIDRVVDATH
PFAAQMSRHAVQACAAAGVPLLALERAPWQAGEGDRWIEVDDLAAAALALGAAPRRVFLGIGRQHLELFAAYPQHAYLVR
LVDPPRAALPFPQVEIVIARGPFDRASDRALLEAHRSEMVVAKNAGGDAAVAKIEAARDLGLPVVMVRRPIVPARLAVAT
VAEVMAWLGHDGAFSERGV
>Mature_259_residues
MLHPAQRLRLLILGGTADATRLATAIAAEPRIEAVLSFAGRTDNPKPPPIPWRVGGFGGVQGLIDYLRAEGIDRVVDATH
PFAAQMSRHAVQACAAAGVPLLALERAPWQAGEGDRWIEVDDLAAAALALGAAPRRVFLGIGRQHLELFAAYPQHAYLVR
LVDPPRAALPFPQVEIVIARGPFDRASDRALLEAHRSEMVVAKNAGGDAAVAKIEAARDLGLPVVMVRRPIVPARLAVAT
VAEVMAWLGHDGAFSERGV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 27567; Mature: 27567

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHPAQRLRLLILGGTADATRLATAIAAEPRIEAVLSFAGRTDNPKPPPIPWRVGGFGGV
CCCHHHEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCH
QGLIDYLRAEGIDRVVDATHPFAAQMSRHAVQACAAAGVPLLALERAPWQAGEGDRWIEV
HHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEH
DDLAAAALALGAAPRRVFLGIGRQHLELFAAYPQHAYLVRLVDPPRAALPFPQVEIVIAR
HHHHHHHHHHCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEEE
GPFDRASDRALLEAHRSEMVVAKNAGGDAAVAKIEAARDLGLPVVMVRRPIVPARLAVAT
CCCCCCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCEEEHHCCCCHHHHHHHH
VAEVMAWLGHDGAFSERGV
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLHPAQRLRLLILGGTADATRLATAIAAEPRIEAVLSFAGRTDNPKPPPIPWRVGGFGGV
CCCHHHEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCH
QGLIDYLRAEGIDRVVDATHPFAAQMSRHAVQACAAAGVPLLALERAPWQAGEGDRWIEV
HHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEH
DDLAAAALALGAAPRRVFLGIGRQHLELFAAYPQHAYLVRLVDPPRAALPFPQVEIVIAR
HHHHHHHHHHCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEEE
GPFDRASDRALLEAHRSEMVVAKNAGGDAAVAKIEAARDLGLPVVMVRRPIVPARLAVAT
CCCCCCCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCEEEHHCCCCHHHHHHHH
VAEVMAWLGHDGAFSERGV
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]