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The map label for this gene is cobF [H]

Identifier: 86750285

GI number: 86750285

Start: 3632044

End: 3632805

Strand: Reverse

Name: cobF [H]

Synonym: RPB_3174

Alternate gene names: 86750285

Gene position: 3632805-3632044 (Counterclockwise)

Preceding gene: 86750292

Following gene: 86750284

Centisome position: 68.14

GC content: 67.19

Gene sequence:

>762_bases
ATGCGCAAGATTCTCCTGATCGGAATGGGCCCCGGCGGCGCCGATTTCCTCACCATGCAGGCGATCGAGGCGCTCGATCG
CGCGCGGGTGTTCTTCCTGCCCGACAAGGGCGCCGAGAAGGCGGAACTGCGCGAAGTCCGCGAGCAGATCTGCCGGCGCT
ACATCACGCAGCCCGACGCGCGCTTCGTCACCGTCGACATTCCGCAGCGCGACGCGGCGGCCGACGACTATCGCGCCACC
GTCGACGATTGGCATGCGCGCATCGCCGCGCGCTATCGTCAGATCCTGATCGACGAACTGCCCGAGGACGGCTGCGGCGC
GTTTCTGGTCTGGGGCGATCCGACGCTGTACGACAGTTCGCTGCGGATCTTGGATCGGTTGCGTGCGGATGGGCTGCCGA
TCGATTACGAGATCATTCCCGGCATCAGCGCCGTGCAGGCGCTGGCGGCGCGGCACCGCATCGCGCTCAACCGGATCGGC
GAATCCGTCGTGATCACGACGGGGCGCAAACTCGGCGCCGCGCGCCGGGTCGCCGACGACACGGTGGTGATGCTCGATGG
CGACGAGACCTTCGCCAAGATCGACCCGACCGGTCTCGACATTTACTGGGGCGCCTATCTCGGCATGAAGGACGAGATCC
TGATCGCCGGGCGGCTCGCCGATGTCGCGTCGGCCATTCAACGCGCCCGGCGCGAGGCGCGCGAATCCAAAGGCTGGATC
ATGGATGCCTATCTGCTGCGCCGCGCCGACGGCGACGTGTAG

Upstream 100 bases:

>100_bases
GCCGGGTCGTCGTGCTTTTCTGGCGCCATCCTCCCACGCCTCTCTTCGTCGTGACGGTCGCGGCTCGCCGGCCGACGAGA
GCGCACGAGTGAAATCGGCC

Downstream 100 bases:

>100_bases
CACTTTCGACCTTTTCGAACGCGCCGCGTGACTGCCGAGACGCATGTTGCGACTTTCGTCGCAGTTGCGCGGCCGTGCGC
GGGTGCGATCTGGTACTCGG

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRKILLIGMGPGGADFLTMQAIEALDRARVFFLPDKGAEKAELREVREQICRRYITQPDARFVTVDIPQRDAAADDYRAT
VDDWHARIAARYRQILIDELPEDGCGAFLVWGDPTLYDSSLRILDRLRADGLPIDYEIIPGISAVQALAARHRIALNRIG
ESVVITTGRKLGAARRVADDTVVMLDGDETFAKIDPTGLDIYWGAYLGMKDEILIAGRLADVASAIQRARREARESKGWI
MDAYLLRRADGDV

Sequences:

>Translated_253_residues
MRKILLIGMGPGGADFLTMQAIEALDRARVFFLPDKGAEKAELREVREQICRRYITQPDARFVTVDIPQRDAAADDYRAT
VDDWHARIAARYRQILIDELPEDGCGAFLVWGDPTLYDSSLRILDRLRADGLPIDYEIIPGISAVQALAARHRIALNRIG
ESVVITTGRKLGAARRVADDTVVMLDGDETFAKIDPTGLDIYWGAYLGMKDEILIAGRLADVASAIQRARREARESKGWI
MDAYLLRRADGDV
>Mature_253_residues
MRKILLIGMGPGGADFLTMQAIEALDRARVFFLPDKGAEKAELREVREQICRRYITQPDARFVTVDIPQRDAAADDYRAT
VDDWHARIAARYRQILIDELPEDGCGAFLVWGDPTLYDSSLRILDRLRADGLPIDYEIIPGISAVQALAARHRIALNRIG
ESVVITTGRKLGAARRVADDTVVMLDGDETFAKIDPTGLDIYWGAYLGMKDEILIAGRLADVASAIQRARREARESKGWI
MDAYLLRRADGDV

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28230; Mature: 28230

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILLIGMGPGGADFLTMQAIEALDRARVFFLPDKGAEKAELREVREQICRRYITQPDA
CCEEEEEEECCCCCHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
RFVTVDIPQRDAAADDYRATVDDWHARIAARYRQILIDELPEDGCGAFLVWGDPTLYDSS
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHH
LRILDRLRADGLPIDYEIIPGISAVQALAARHRIALNRIGESVVITTGRKLGAARRVADD
HHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCC
TVVMLDGDETFAKIDPTGLDIYWGAYLGMKDEILIAGRLADVASAIQRARREARESKGWI
EEEEEECCCCEEEECCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
MDAYLLRRADGDV
HHHHHHHHCCCCC
>Mature Secondary Structure
MRKILLIGMGPGGADFLTMQAIEALDRARVFFLPDKGAEKAELREVREQICRRYITQPDA
CCEEEEEEECCCCCHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
RFVTVDIPQRDAAADDYRATVDDWHARIAARYRQILIDELPEDGCGAFLVWGDPTLYDSS
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHH
LRILDRLRADGLPIDYEIIPGISAVQALAARHRIALNRIGESVVITTGRKLGAARRVADD
HHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCC
TVVMLDGDETFAKIDPTGLDIYWGAYLGMKDEILIAGRLADVASAIQRARREARESKGWI
EEEEEECCCCEEEECCCCCEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
MDAYLLRRADGDV
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]