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The map label for this gene is appC [H]

Identifier: 86750242

GI number: 86750242

Start: 3577689

End: 3578528

Strand: Reverse

Name: appC [H]

Synonym: RPB_3131

Alternate gene names: 86750242

Gene position: 3578528-3577689 (Counterclockwise)

Preceding gene: 86750243

Following gene: 86750241

Centisome position: 67.12

GC content: 67.26

Gene sequence:

>840_bases
ATGGATCGGCTGAAGACCTTCCTGAGTCACCCGACCGGCCTGATCGGCCTGGTGATCCTGATCGGCGTCATCGTGCTCGC
GGTCTTGGCGCCCGTGATCTTTCCCGAAGACCCTTGGGAGATGGTCGCGGCGCCGTTCCAGCCGCCGGCCAGCGAGGGGC
TGCCGCTCGGCTCCGACATGCTCGGCCGGAACGTCGCCGCGGGGATCGCCTACGGCGCCCGGGTATCGCTGACGATCGGC
GTCGCCTCGACGCTGGCGGCGCTGTGCATCGGGGTGGTGATCGGGGCGATCGCCGGCTATTTCGGCGGCCGGGTCGACGA
GCTGATGATGCGTATCACCGAACTGTTCCAGACCATTCCGGGCTTCATCCTCGCCATCCTGCTGGTGGCCACGATCGGCC
CGACGCTGACCAACGTGATCATCTCGATCGGTGCGGTGAGCTGGCCGCCGCTGGCGCGGCTGACGCGGGCGGAGTTCATG
CGCCTGCGCGGCCGCGAGTTCGTCCAGGCGGCGGTGTGTCAGGGCCAGGCGCCTCTGGTGGTGGCGCTCCGGCACATCCT
ACCCAATGCGATCTCGCCGATCATCGTCACCGGCTCGCTGACGATCGCGACCGCGATCCTGATCGAGAGTGCGCTCAGCT
TCATGGGGCTCGGCGATCCCAATCTGATGTCGTGGGGGCTGATGATCGGCGCGTCGCGCACCGTGATCCGTCAGGCGTGG
TGGATGAGCATGTTTCCCGGCATCGCGATCCTGCTGACCGTGCTGGCGATCAATCTGGTCGGCGAGGGGCTGAACGACAC
CCTGAACCCGCGCATCTCGCGAAAGGCGCGCAACGCATGA

Upstream 100 bases:

>100_bases
GTCGGTGATCGTCATCGGGCTCAATCTGCTGACCGACGCGATCTACCGGATCGTCGATCCGCGCGTGTCGTTGCGTGCTG
CATCCTGAGCGGAGGTTGAG

Downstream 100 bases:

>100_bases
ACGACGATATTCTGCTGTCCGTCGAAAACTTGTCGGTGGCACTGCCGAGGGGCGGCGATCGCAGTCACGCTGTCGCGGAG
GTGTCGCTCAGCGTACGGCG

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDRLKTFLSHPTGLIGLVILIGVIVLAVLAPVIFPEDPWEMVAAPFQPPASEGLPLGSDMLGRNVAAGIAYGARVSLTIG
VASTLAALCIGVVIGAIAGYFGGRVDELMMRITELFQTIPGFILAILLVATIGPTLTNVIISIGAVSWPPLARLTRAEFM
RLRGREFVQAAVCQGQAPLVVALRHILPNAISPIIVTGSLTIATAILIESALSFMGLGDPNLMSWGLMIGASRTVIRQAW
WMSMFPGIAILLTVLAINLVGEGLNDTLNPRISRKARNA

Sequences:

>Translated_279_residues
MDRLKTFLSHPTGLIGLVILIGVIVLAVLAPVIFPEDPWEMVAAPFQPPASEGLPLGSDMLGRNVAAGIAYGARVSLTIG
VASTLAALCIGVVIGAIAGYFGGRVDELMMRITELFQTIPGFILAILLVATIGPTLTNVIISIGAVSWPPLARLTRAEFM
RLRGREFVQAAVCQGQAPLVVALRHILPNAISPIIVTGSLTIATAILIESALSFMGLGDPNLMSWGLMIGASRTVIRQAW
WMSMFPGIAILLTVLAINLVGEGLNDTLNPRISRKARNA
>Mature_279_residues
MDRLKTFLSHPTGLIGLVILIGVIVLAVLAPVIFPEDPWEMVAAPFQPPASEGLPLGSDMLGRNVAAGIAYGARVSLTIG
VASTLAALCIGVVIGAIAGYFGGRVDELMMRITELFQTIPGFILAILLVATIGPTLTNVIISIGAVSWPPLARLTRAEFM
RLRGREFVQAAVCQGQAPLVVALRHILPNAISPIIVTGSLTIATAILIESALSFMGLGDPNLMSWGLMIGASRTVIRQAW
WMSMFPGIAILLTVLAINLVGEGLNDTLNPRISRKARNA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=271, Percent_Identity=36.1623616236162, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787498, Length=275, Percent_Identity=32.7272727272727, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787760, Length=267, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789964, Length=258, Percent_Identity=39.1472868217054, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1789889, Length=242, Percent_Identity=36.7768595041322, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=31.7596566523605, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787549, Length=269, Percent_Identity=28.996282527881, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29494; Mature: 29494

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLKTFLSHPTGLIGLVILIGVIVLAVLAPVIFPEDPWEMVAAPFQPPASEGLPLGSDM
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCHHH
LGRNVAAGIAYGARVSLTIGVASTLAALCIGVVIGAIAGYFGGRVDELMMRITELFQTIP
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GFILAILLVATIGPTLTNVIISIGAVSWPPLARLTRAEFMRLRGREFVQAAVCQGQAPLV
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VALRHILPNAISPIIVTGSLTIATAILIESALSFMGLGDPNLMSWGLMIGASRTVIRQAW
HHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHH
WMSMFPGIAILLTVLAINLVGEGLNDTLNPRISRKARNA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MDRLKTFLSHPTGLIGLVILIGVIVLAVLAPVIFPEDPWEMVAAPFQPPASEGLPLGSDM
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCHHH
LGRNVAAGIAYGARVSLTIGVASTLAALCIGVVIGAIAGYFGGRVDELMMRITELFQTIP
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GFILAILLVATIGPTLTNVIISIGAVSWPPLARLTRAEFMRLRGREFVQAAVCQGQAPLV
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VALRHILPNAISPIIVTGSLTIATAILIESALSFMGLGDPNLMSWGLMIGASRTVIRQAW
HHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHH
WMSMFPGIAILLTVLAINLVGEGLNDTLNPRISRKARNA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]