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The map label for this gene is cutL [H]

Identifier: 86750215

GI number: 86750215

Start: 3534345

End: 3536648

Strand: Reverse

Name: cutL [H]

Synonym: RPB_3102

Alternate gene names: 86750215

Gene position: 3536648-3534345 (Counterclockwise)

Preceding gene: 86750216

Following gene: 86750214

Centisome position: 66.33

GC content: 64.58

Gene sequence:

>2304_bases
ATGAGCATGACGAAGGTCGCCAATTCGTACATTGGTCGCCCGATGGAGCGGGTCGAGGATCTGCGCATGGTGCGCGGGCG
CGGCACTTATGTGGCCGACGTCAACCGGCCGAACCAACTTTATGCGGTCGTGCTGCGCAGCTCGGTGGCGCACGGCATCA
TCAGATCGATCGACGTGTCCGCTGCGCTGGCGCTCGACGGCGTTCACCGTGTCCTGACGGCGAACGATTTCGGCGCCGAG
GTGCCGGTGATCCCGCTGCGCTTGCAACCGCTGCCGCAACTCGAGCCGTTCCATCAGCCGGTGGTGGCCTCGGGCAAGGT
CCGCTATGTCGGCGAACCCGTCGCGGTGGTGATCGCCGACAGCGCGGCGATTGCGGAGGATGCGCTGGAGCGGATCGTGG
TCGACATCGACCCGTTGCCGGCGATCGCCAACCGACAGCAGGCGGAAGCGATGGACGCGGTGCTGTTCGAACAGCATCAG
TCGAATGTCGCCATCACCTGGACGGCGTTTCGCGGCGACGCCGACGACGCGTTCGAGACCGCCGACTATGTCCGCCGCGA
TCGCTTCAAGATCCAGCGACACGCGGCGATGTTCATGGAGCCGCGCGGCTTCGTCGCCGATTGGGATGCGGCTGCCGGCA
AGCTCACCGTCTGGGGCGCGGCGAAAACGGCGTGGTACAATCGTCGCGTGCTCGCCGCGGCGCTCGGGCTGGCGCTGGAG
GCCGTCGACCTGATCGAGGTCGATGTCGGCGGTGGCTTCGGCTCGCGCGGCGAATTCTATCCGGAGGACTATCTGATTCC
GGCGGCCGCCAAGATCGTCGGGCGGCCGGTCAAATGGCTCGAAGATCGCCGCGAACACATGATGAGCGCCAACCACGCGC
GCGATATCGAATGCGACGTCGAGTTCGCGATGTCGAAGGAGGGGCGCTTCATCGGCCTGCGTGGCCAAATCTGGGCCGAC
ATCGGCGCCTATGTCCGCACTAACGGATCGGTCGGCCCGCGCAATGTCGCGCAATACATGTCGGGGCCGTACGCGATCGA
GCACATCGATCTGAAAAGTTCGATGCTCACCACCAACAAGACCCCGTCGGGGACCTATCGCGGACCCGGGCGCTTCGAGA
CCGATTTCATTCGCGAGCGCATGATCGATCTGGCGGCTCGCGATCTGAACATCGATCGCGTCGAGCTGCGGCGGCGCAAT
CTCGTTGCCGACGCCCAGATGCCGTATCCGCTGGCGTCGATCACCCCCTATGACAGCTCGACCGAGCTCGACAGTGGCGA
CTACCACGCCGTGTTCGATCGCTGCCTGAAGGAATTCGCCTGGGCCGACAAGAAGCACCTCAGCGGCAAGCTGATCGATG
GCTACTATCACGGGCTCGCCGTCGGCAGCTTCATCGAGGGCGGCGCTGCCGGCCCGAAAGAAGAGGTGCGGCTGGTGCTC
GAAATTGGCGGCGGGCTGACGGCCTATCTCGGCTCGTCGTCGGTCGGACAAGGGCTCGAGACCATCATGGCACAGATCGC
CGCGGACGCCACCGAGATCGCCTACGACAGAATCACGGTCCGCCACGGCTCGACTACCGACGTCAAGGACGGCTACGGCG
CCTACCATTCGCGCTCGACGGTGATGGGCGGCTCGGCGATCCTGCTCGCTGCCGAAAAGCTGAAGCTGTTGATCCGGCAG
ACGGCTGCCGCCCGCTTCGGCTGCTCGCTGGAGCAGGTGACGATCGACGGCGAAACCGTGAGGCATGAGGCCAAGCATCT
CGCGTTCGCCGATCTGGTCGAGACGCCGCTCGAAGTCGAGGCGGAATTTCTCAACAAGAAATACACCTGGGCCTACGGCA
CGCAGGCGGCGCATGTCGCGGTCGACCCGGGCACCGGACACGTCAAGGTTCTCGACTACATGTCGGTCGAGGATGTCGGC
CGGATGATCAATCCGCTGACCTTGCACGGGCAGGCGATCGGCTCGATCGTGCAGGGGCTGGGCGGAACGTTCCTGGAGCA
TCTGGTCTACGACGATGAAGGCCAACTGCTCACCGGTTCATTCGCCGACTATTTGATGCCGACCGCCTCCGACTTTCCGA
ATATCCGGTCGATCACGCTGGAACTGAAGCCGTGTCCGAACAATCCGCTCGGCGCCAAGGGGGCGGGCGAAGGGGGGCTG
ATTCCGGTCGGCGGCATCATGGCCAACGCGGTTGCGGACGCGCTGTCTCACCTCGACGTTCAGCCGATGGAGCTGCCGCT
GTCGCCGCCGCGAATCTGGCAAATGGTTCAGGATGCCGAGGGCAGGATTCGTGCAAAGTCCTAA

Upstream 100 bases:

>100_bases
TCCGCGAGGTGCTGTCCGGCAACCTCTGCCGCTGCACTGGTTACGTCCCCATCGTCGACGCGGTAATGGAAGCGCGCGCC
GCCTATGCCGAGGCGCAGCG

Downstream 100 bases:

>100_bases
GTTCGATTGATTTTTCCTCGCGGCCCAGCATAGTTGCGGACGGGCAGGGCCGCCTATTTCGGCCGCCGCTCGGCCATGGA
GGATAGCGGCTTGGCGCGCA

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MSMTKVANSYIGRPMERVEDLRMVRGRGTYVADVNRPNQLYAVVLRSSVAHGIIRSIDVSAALALDGVHRVLTANDFGAE
VPVIPLRLQPLPQLEPFHQPVVASGKVRYVGEPVAVVIADSAAIAEDALERIVVDIDPLPAIANRQQAEAMDAVLFEQHQ
SNVAITWTAFRGDADDAFETADYVRRDRFKIQRHAAMFMEPRGFVADWDAAAGKLTVWGAAKTAWYNRRVLAAALGLALE
AVDLIEVDVGGGFGSRGEFYPEDYLIPAAAKIVGRPVKWLEDRREHMMSANHARDIECDVEFAMSKEGRFIGLRGQIWAD
IGAYVRTNGSVGPRNVAQYMSGPYAIEHIDLKSSMLTTNKTPSGTYRGPGRFETDFIRERMIDLAARDLNIDRVELRRRN
LVADAQMPYPLASITPYDSSTELDSGDYHAVFDRCLKEFAWADKKHLSGKLIDGYYHGLAVGSFIEGGAAGPKEEVRLVL
EIGGGLTAYLGSSSVGQGLETIMAQIAADATEIAYDRITVRHGSTTDVKDGYGAYHSRSTVMGGSAILLAAEKLKLLIRQ
TAAARFGCSLEQVTIDGETVRHEAKHLAFADLVETPLEVEAEFLNKKYTWAYGTQAAHVAVDPGTGHVKVLDYMSVEDVG
RMINPLTLHGQAIGSIVQGLGGTFLEHLVYDDEGQLLTGSFADYLMPTASDFPNIRSITLELKPCPNNPLGAKGAGEGGL
IPVGGIMANAVADALSHLDVQPMELPLSPPRIWQMVQDAEGRIRAKS

Sequences:

>Translated_767_residues
MSMTKVANSYIGRPMERVEDLRMVRGRGTYVADVNRPNQLYAVVLRSSVAHGIIRSIDVSAALALDGVHRVLTANDFGAE
VPVIPLRLQPLPQLEPFHQPVVASGKVRYVGEPVAVVIADSAAIAEDALERIVVDIDPLPAIANRQQAEAMDAVLFEQHQ
SNVAITWTAFRGDADDAFETADYVRRDRFKIQRHAAMFMEPRGFVADWDAAAGKLTVWGAAKTAWYNRRVLAAALGLALE
AVDLIEVDVGGGFGSRGEFYPEDYLIPAAAKIVGRPVKWLEDRREHMMSANHARDIECDVEFAMSKEGRFIGLRGQIWAD
IGAYVRTNGSVGPRNVAQYMSGPYAIEHIDLKSSMLTTNKTPSGTYRGPGRFETDFIRERMIDLAARDLNIDRVELRRRN
LVADAQMPYPLASITPYDSSTELDSGDYHAVFDRCLKEFAWADKKHLSGKLIDGYYHGLAVGSFIEGGAAGPKEEVRLVL
EIGGGLTAYLGSSSVGQGLETIMAQIAADATEIAYDRITVRHGSTTDVKDGYGAYHSRSTVMGGSAILLAAEKLKLLIRQ
TAAARFGCSLEQVTIDGETVRHEAKHLAFADLVETPLEVEAEFLNKKYTWAYGTQAAHVAVDPGTGHVKVLDYMSVEDVG
RMINPLTLHGQAIGSIVQGLGGTFLEHLVYDDEGQLLTGSFADYLMPTASDFPNIRSITLELKPCPNNPLGAKGAGEGGL
IPVGGIMANAVADALSHLDVQPMELPLSPPRIWQMVQDAEGRIRAKS
>Mature_766_residues
SMTKVANSYIGRPMERVEDLRMVRGRGTYVADVNRPNQLYAVVLRSSVAHGIIRSIDVSAALALDGVHRVLTANDFGAEV
PVIPLRLQPLPQLEPFHQPVVASGKVRYVGEPVAVVIADSAAIAEDALERIVVDIDPLPAIANRQQAEAMDAVLFEQHQS
NVAITWTAFRGDADDAFETADYVRRDRFKIQRHAAMFMEPRGFVADWDAAAGKLTVWGAAKTAWYNRRVLAAALGLALEA
VDLIEVDVGGGFGSRGEFYPEDYLIPAAAKIVGRPVKWLEDRREHMMSANHARDIECDVEFAMSKEGRFIGLRGQIWADI
GAYVRTNGSVGPRNVAQYMSGPYAIEHIDLKSSMLTTNKTPSGTYRGPGRFETDFIRERMIDLAARDLNIDRVELRRRNL
VADAQMPYPLASITPYDSSTELDSGDYHAVFDRCLKEFAWADKKHLSGKLIDGYYHGLAVGSFIEGGAAGPKEEVRLVLE
IGGGLTAYLGSSSVGQGLETIMAQIAADATEIAYDRITVRHGSTTDVKDGYGAYHSRSTVMGGSAILLAAEKLKLLIRQT
AAARFGCSLEQVTIDGETVRHEAKHLAFADLVETPLEVEAEFLNKKYTWAYGTQAAHVAVDPGTGHVKVLDYMSVEDVGR
MINPLTLHGQAIGSIVQGLGGTFLEHLVYDDEGQLLTGSFADYLMPTASDFPNIRSITLELKPCPNNPLGAKGAGEGGLI
PVGGIMANAVADALSHLDVQPMELPLSPPRIWQMVQDAEGRIRAKS

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=742, Percent_Identity=25.3369272237197, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI71773480, Length=781, Percent_Identity=24.3277848911652, Blast_Score=122, Evalue=1e-27,
Organism=Escherichia coli, GI1789246, Length=777, Percent_Identity=25.4826254826255, Blast_Score=197, Evalue=3e-51,
Organism=Escherichia coli, GI1789230, Length=770, Percent_Identity=26.2337662337662, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786478, Length=756, Percent_Identity=26.984126984127, Blast_Score=149, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17540638, Length=797, Percent_Identity=23.4629861982434, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17539860, Length=702, Percent_Identity=21.2250712250712, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17737937, Length=781, Percent_Identity=24.9679897567222, Blast_Score=132, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83529; Mature: 83398

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTKVANSYIGRPMERVEDLRMVRGRGTYVADVNRPNQLYAVVLRSSVAHGIIRSIDVS
CCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCHH
AALALDGVHRVLTANDFGAEVPVIPLRLQPLPQLEPFHQPVVASGKVRYVGEPVAVVIAD
HHHHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEC
SAAIAEDALERIVVDIDPLPAIANRQQAEAMDAVLFEQHQSNVAITWTAFRGDADDAFET
CHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
ADYVRRDRFKIQRHAAMFMEPRGFVADWDAAAGKLTVWGAAKTAWYNRRVLAAALGLALE
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
AVDLIEVDVGGGFGSRGEFYPEDYLIPAAAKIVGRPVKWLEDRREHMMSANHARDIECDV
HEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEECE
EFAMSKEGRFIGLRGQIWADIGAYVRTNGSVGPRNVAQYMSGPYAIEHIDLKSSMLTTNK
EEEECCCCCEEEECCCHHHCCCCCEECCCCCCHHHHHHHCCCCEEEEEEECCHHHEECCC
TPSGTYRGPGRFETDFIRERMIDLAARDLNIDRVELRRRNLVADAQMPYPLASITPYDSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCEECCCCCCCCCCCCCCCCC
TELDSGDYHAVFDRCLKEFAWADKKHLSGKLIDGYYHGLAVGSFIEGGAAGPKEEVRLVL
CCCCCCCHHHHHHHHHHHHHCCCHHHCCCEEECHHHHHHHHHHHHCCCCCCCHHHEEEEE
EIGGGLTAYLGSSSVGQGLETIMAQIAADATEIAYDRITVRHGSTTDVKDGYGAYHSRST
EECCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCCCCCCCCCCCE
VMGGSAILLAAEKLKLLIRQTAAARFGCSLEQVTIDGETVRHEAKHLAFADLVETPLEVE
ECCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHH
AEFLNKKYTWAYGTQAAHVAVDPGTGHVKVLDYMSVEDVGRMINPLTLHGQAIGSIVQGL
HHHCCCEEEEEECCCEEEEEECCCCCCEEEEECCCHHHHHHHHCCEEECHHHHHHHHHHH
GGTFLEHLVYDDEGQLLTGSFADYLMPTASDFPNIRSITLELKPCPNNPLGAKGAGEGGL
HHHHHHHHEECCCCCEEECCHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCE
IPVGGIMANAVADALSHLDVQPMELPLSPPRIWQMVQDAEGRIRAKS
EECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
SMTKVANSYIGRPMERVEDLRMVRGRGTYVADVNRPNQLYAVVLRSSVAHGIIRSIDVS
CHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCHH
AALALDGVHRVLTANDFGAEVPVIPLRLQPLPQLEPFHQPVVASGKVRYVGEPVAVVIAD
HHHHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEC
SAAIAEDALERIVVDIDPLPAIANRQQAEAMDAVLFEQHQSNVAITWTAFRGDADDAFET
CHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
ADYVRRDRFKIQRHAAMFMEPRGFVADWDAAAGKLTVWGAAKTAWYNRRVLAAALGLALE
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
AVDLIEVDVGGGFGSRGEFYPEDYLIPAAAKIVGRPVKWLEDRREHMMSANHARDIECDV
HEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEECE
EFAMSKEGRFIGLRGQIWADIGAYVRTNGSVGPRNVAQYMSGPYAIEHIDLKSSMLTTNK
EEEECCCCCEEEECCCHHHCCCCCEECCCCCCHHHHHHHCCCCEEEEEEECCHHHEECCC
TPSGTYRGPGRFETDFIRERMIDLAARDLNIDRVELRRRNLVADAQMPYPLASITPYDSS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCEECCCCCCCCCCCCCCCCC
TELDSGDYHAVFDRCLKEFAWADKKHLSGKLIDGYYHGLAVGSFIEGGAAGPKEEVRLVL
CCCCCCCHHHHHHHHHHHHHCCCHHHCCCEEECHHHHHHHHHHHHCCCCCCCHHHEEEEE
EIGGGLTAYLGSSSVGQGLETIMAQIAADATEIAYDRITVRHGSTTDVKDGYGAYHSRST
EECCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCCCCCCCCCCCE
VMGGSAILLAAEKLKLLIRQTAAARFGCSLEQVTIDGETVRHEAKHLAFADLVETPLEVE
ECCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHH
AEFLNKKYTWAYGTQAAHVAVDPGTGHVKVLDYMSVEDVGRMINPLTLHGQAIGSIVQGL
HHHCCCEEEEEECCCEEEEEECCCCCCEEEEECCCHHHHHHHHCCEEECHHHHHHHHHHH
GGTFLEHLVYDDEGQLLTGSFADYLMPTASDFPNIRSITLELKPCPNNPLGAKGAGEGGL
HHHHHHHHEECCCCCEEECCHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCE
IPVGGIMANAVADALSHLDVQPMELPLSPPRIWQMVQDAEGRIRAKS
EECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]