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The map label for this gene is csd [H]

Identifier: 86750107

GI number: 86750107

Start: 3403472

End: 3404758

Strand: Reverse

Name: csd [H]

Synonym: RPB_2990

Alternate gene names: 86750107

Gene position: 3404758-3403472 (Counterclockwise)

Preceding gene: 86750108

Following gene: 86750106

Centisome position: 63.86

GC content: 63.25

Gene sequence:

>1287_bases
ATGCGGCACTGCTGCGATCGCTCTCGAGTTGGAAGGCCTGACATGGCGCATCCCGCGGTTTCGAATGGGTCCTACGACGT
CGCCAAAGTCCGCGAGGATTTTCCGGCGCTGGCGCTGAAGGTTTACGGCAAGGATCTGGTGTATCTCGACAACGCCGCCT
CGGCGCAGAAGCCGCGCGCCGTGCTGGAGCGGATGACCAAGGCGTATGAGAGCGAATACGCCAATGTGCATCGCGGGCTG
CATTATCTCGCCAACGCGGCGACCGAAGCCTATGAGGGCGGTCGCACCCGCGTGCAGCATTTCCTCAACGCCAAGCGGCC
GGAAGAGATCATCTTCACCCGCAACGCCACCGAGGCGATCAATCTGGTGGCGTCGTCGTTCGGCGCGCCGAATATCGGCG
AGGGCGACGAGATCGTGCTCTCGATCATGGAGCACCATTCCAACATCGTGCCGTGGCACTTCTTGCGCGAACGTCAGGGT
GCTGTTCTCAAATGGGCGCCGGTCGACGACGACGGCAATTTCCTGATCGACGAATTCGAGAAGCTGCTGTCGCCGAAGAC
CAAGCTGGTCGCGATCACGCAGATGTCGAACGCGCTCGGCACCATCGTGCCGGTGAAAGAGGTGGTGAAGCTGGCGCACG
ACCGCGGCATTCCGGTGCTGGTCGACGGCAGCCAGGGCGCGGTGCATCTCACCATCGACGTCCAGGACATCGACTGCGAT
TTCTACATCATGACCGGCCACAAGCTGTACGGCCCGACCGGGATCGGCGTGCTGTACGGCAAATACGACGTCCTCGCCAA
GATGCGGCCGTTCAACGGCGGCGGCGAGATGATTCGCGAAGTGGCGCAGGACTGGGTGACCTACGGCGACCCGCCGCACC
GGTTCGAGGCCGGCACCCCGGCGATCGTCGAGGCGGTCGGGCTCGGGGCGGCGATCGACTACGTCAATTCGATCGGCAAG
GAGCGCATCGCCGCGCACGAACACGATCTTTTGACGTATGCGGAACAGCGATTGCGCGAGATCAATTCGCTGCGCATCAT
CGGCACCGCCAAGGGCAAGGGGCCGGTGATTTCCTTCGAGATGAAGGGCGCGCACCCGCACGACATCGCCACCGTGATCG
ACCGCCAGGGCATCGCGGTGCGGGCGGGAACCCATTGCGTGATGCCGTTGCTGGAGCGGTTCCAGGTCACGGCGACGTGC
CGGGCGTCGTTCGGCATGTATAATACCCGTGAGGAAGTCGACCAACTCGCTAATGCGCTGATCAAGGCGCGGGACCTGTT
CGCATGA

Upstream 100 bases:

>100_bases
GTAGCGATGATCCGGGTGAGGGGGCGTCTCGCCGAGTCTCGGCCTCGCGGACACGCCCCCTCACCCCAGCCCTCTCCCCG
CGCGCGGGGAGAGGGAGTCG

Downstream 100 bases:

>100_bases
CCGATACGATCGAAGCCAAGGCCAATATGCAGACCGTCTCGGCGCTGCCGCCCGAGGAGACCGAGCGGCTCGGCACCGAG
ATCGTCGCGGCGCTGAAGAC

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MRHCCDRSRVGRPDMAHPAVSNGSYDVAKVREDFPALALKVYGKDLVYLDNAASAQKPRAVLERMTKAYESEYANVHRGL
HYLANAATEAYEGGRTRVQHFLNAKRPEEIIFTRNATEAINLVASSFGAPNIGEGDEIVLSIMEHHSNIVPWHFLRERQG
AVLKWAPVDDDGNFLIDEFEKLLSPKTKLVAITQMSNALGTIVPVKEVVKLAHDRGIPVLVDGSQGAVHLTIDVQDIDCD
FYIMTGHKLYGPTGIGVLYGKYDVLAKMRPFNGGGEMIREVAQDWVTYGDPPHRFEAGTPAIVEAVGLGAAIDYVNSIGK
ERIAAHEHDLLTYAEQRLREINSLRIIGTAKGKGPVISFEMKGAHPHDIATVIDRQGIAVRAGTHCVMPLLERFQVTATC
RASFGMYNTREEVDQLANALIKARDLFA

Sequences:

>Translated_428_residues
MRHCCDRSRVGRPDMAHPAVSNGSYDVAKVREDFPALALKVYGKDLVYLDNAASAQKPRAVLERMTKAYESEYANVHRGL
HYLANAATEAYEGGRTRVQHFLNAKRPEEIIFTRNATEAINLVASSFGAPNIGEGDEIVLSIMEHHSNIVPWHFLRERQG
AVLKWAPVDDDGNFLIDEFEKLLSPKTKLVAITQMSNALGTIVPVKEVVKLAHDRGIPVLVDGSQGAVHLTIDVQDIDCD
FYIMTGHKLYGPTGIGVLYGKYDVLAKMRPFNGGGEMIREVAQDWVTYGDPPHRFEAGTPAIVEAVGLGAAIDYVNSIGK
ERIAAHEHDLLTYAEQRLREINSLRIIGTAKGKGPVISFEMKGAHPHDIATVIDRQGIAVRAGTHCVMPLLERFQVTATC
RASFGMYNTREEVDQLANALIKARDLFA
>Mature_428_residues
MRHCCDRSRVGRPDMAHPAVSNGSYDVAKVREDFPALALKVYGKDLVYLDNAASAQKPRAVLERMTKAYESEYANVHRGL
HYLANAATEAYEGGRTRVQHFLNAKRPEEIIFTRNATEAINLVASSFGAPNIGEGDEIVLSIMEHHSNIVPWHFLRERQG
AVLKWAPVDDDGNFLIDEFEKLLSPKTKLVAITQMSNALGTIVPVKEVVKLAHDRGIPVLVDGSQGAVHLTIDVQDIDCD
FYIMTGHKLYGPTGIGVLYGKYDVLAKMRPFNGGGEMIREVAQDWVTYGDPPHRFEAGTPAIVEAVGLGAAIDYVNSIGK
ERIAAHEHDLLTYAEQRLREINSLRIIGTAKGKGPVISFEMKGAHPHDIATVIDRQGIAVRAGTHCVMPLLERFQVTATC
RASFGMYNTREEVDQLANALIKARDLFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=392, Percent_Identity=23.2142857142857, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI156713448, Length=438, Percent_Identity=27.3972602739726, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=47.5247524752475, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1789175, Length=404, Percent_Identity=40.0990099009901, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI48994898, Length=388, Percent_Identity=26.0309278350515, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25143064, Length=265, Percent_Identity=27.1698113207547, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193211090, Length=376, Percent_Identity=23.936170212766, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=237, Percent_Identity=29.957805907173, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20129463, Length=437, Percent_Identity=25.629290617849, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 47225; Mature: 47225

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHCCDRSRVGRPDMAHPAVSNGSYDVAKVREDFPALALKVYGKDLVYLDNAASAQKPRA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHEEEECCCCEEEECCCCCCCCHHH
VLERMTKAYESEYANVHRGLHYLANAATEAYEGGRTRVQHFLNAKRPEEIIFTRNATEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCHHHHH
NLVASSFGAPNIGEGDEIVLSIMEHHSNIVPWHFLRERQGAVLKWAPVDDDGNFLIDEFE
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHH
KLLSPKTKLVAITQMSNALGTIVPVKEVVKLAHDRGIPVLVDGSQGAVHLTIDVQDIDCD
HHHCCCCEEEEEEEHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEECCEE
FYIMTGHKLYGPTGIGVLYGKYDVLAKMRPFNGGGEMIREVAQDWVTYGDPPHRFEAGTP
EEEEECCEEECCCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
AIVEAVGLGAAIDYVNSIGKERIAAHEHDLLTYAEQRLREINSLRIIGTAKGKGPVISFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEE
MKGAHPHDIATVIDRQGIAVRAGTHCVMPLLERFQVTATCRASFGMYNTREEVDQLANAL
ECCCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IKARDLFA
HHHHHHCC
>Mature Secondary Structure
MRHCCDRSRVGRPDMAHPAVSNGSYDVAKVREDFPALALKVYGKDLVYLDNAASAQKPRA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHEEEECCCCEEEECCCCCCCCHHH
VLERMTKAYESEYANVHRGLHYLANAATEAYEGGRTRVQHFLNAKRPEEIIFTRNATEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEECCHHHHH
NLVASSFGAPNIGEGDEIVLSIMEHHSNIVPWHFLRERQGAVLKWAPVDDDGNFLIDEFE
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHH
KLLSPKTKLVAITQMSNALGTIVPVKEVVKLAHDRGIPVLVDGSQGAVHLTIDVQDIDCD
HHHCCCCEEEEEEEHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEECCEE
FYIMTGHKLYGPTGIGVLYGKYDVLAKMRPFNGGGEMIREVAQDWVTYGDPPHRFEAGTP
EEEEECCEEECCCCCEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCH
AIVEAVGLGAAIDYVNSIGKERIAAHEHDLLTYAEQRLREINSLRIIGTAKGKGPVISFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEE
MKGAHPHDIATVIDRQGIAVRAGTHCVMPLLERFQVTATCRASFGMYNTREEVDQLANAL
ECCCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
IKARDLFA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]