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The map label for this gene is kamA [H]

Identifier: 86750071

GI number: 86750071

Start: 3363230

End: 3364321

Strand: Reverse

Name: kamA [H]

Synonym: RPB_2954

Alternate gene names: 86750071

Gene position: 3364321-3363230 (Counterclockwise)

Preceding gene: 86750072

Following gene: 86750070

Centisome position: 63.1

GC content: 67.03

Gene sequence:

>1092_bases
ATGAGCAGGGTCACACGATTGCAAACGCCCGCCGCCACAACACTGCGGCAACCCTCTGAGCTGATCGCGCAAGGTCTCGC
GCCGGCGGAGTCGCGCGACGATCTCGAACAGGTCGCGGCACGCTACGCGATCGCGGTGACGCCCGATGTCGCGGCGCTGA
TCGATCCGAACGATCCCCACGATCCGATCGCGCGGCAATACATCCCGCGTGCCGACGAACTCGTCACGCTGCCGATCGAG
CGCGACGATCCGATCGGCGACGGCGCCCATGCGCCGGTCGAGGGCATCGTGCATCGCCACCGCGACCGCGTGCTGCTGAA
GCTGGTGCATGTCTGCGCGGTGTATTGCCGGTTCTGTTTCCGCCGCGAGACGATCGGCCCCGGCAAGGACAACGCGCTGT
CGCGCGAGGCGACCGCGGCGGCGCTCGACTACATCCGGGCCCACCCGGAAATCTGGGAGGTGATCTTCACCGGCGGCGAT
CCGTTGATGCTGTCGCCGCGCCGGATGGCCGAGATCATGGCCGAACTGGCGACCATCGCGCACGTCAAGATCATCCGCTT
CCACACCCGCGTGCCGGTTGCCGATCCTGCGCGGATCACGCCGGAGCTGGTGCGGGCGTTGCAGACACCCGGGAAAACCA
CCTGGGTCGCGCTTCACGCCAACCACCCGCGCGAGCTCACCGCGGCTGCGCGCGCCGCGTGTGCGATGCTGATAGATGCC
GGGATTCCGATGGTCAGCCAGTCGGTGCTGTTGCGCGGTGTGAACGATGATTCGGAGACGCTGGAAGCCTTGATGCGCGG
CTTCGTCGAATGCCGGATCAAGCCGTATTATCTGCATCACGGCGACCTCGCGCCGGGCACCGCGCATCTGCGCACCACGA
TCGCGGAAGGGCAGGCGCTGATGCGGGCGCTGCGCGGCCGCGTCTCCGGCCTGTGCCAGCCGGAATACGTGCTCGACATT
CCCGGCGGCTACGGCAAGGCGCCGATCGGTCCGAACTATTTGACGGGCGAGGATGGAACAGTCGCGGATTCGCGCTATCG
TGTCCGCGACTATTGCGGTGACGTCCATCTCTATCCGCCCGGCTCGTGCTGA

Upstream 100 bases:

>100_bases
CGAGCGGCGTGGCGCTCGGCTTCGACCGGCTGGTGATGCTGGCGGCGGGCGCGACCAGCATCGATCAGGTGGTGTGGACG
CCGCCGGCGGGCGAGGCGTC

Downstream 100 bases:

>100_bases
GCGACCTCGCGACGCAACGGGAGACGGCAACCGCAACGTCGATCATGCGTTGTCGCGCTGGATGCGGCCCGACAGCGCCA
CGGCAAGGAGAACGAGATGA

Product: hypothetical protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSRVTRLQTPAATTLRQPSELIAQGLAPAESRDDLEQVAARYAIAVTPDVAALIDPNDPHDPIARQYIPRADELVTLPIE
RDDPIGDGAHAPVEGIVHRHRDRVLLKLVHVCAVYCRFCFRRETIGPGKDNALSREATAAALDYIRAHPEIWEVIFTGGD
PLMLSPRRMAEIMAELATIAHVKIIRFHTRVPVADPARITPELVRALQTPGKTTWVALHANHPRELTAAARAACAMLIDA
GIPMVSQSVLLRGVNDDSETLEALMRGFVECRIKPYYLHHGDLAPGTAHLRTTIAEGQALMRALRGRVSGLCQPEYVLDI
PGGYGKAPIGPNYLTGEDGTVADSRYRVRDYCGDVHLYPPGSC

Sequences:

>Translated_363_residues
MSRVTRLQTPAATTLRQPSELIAQGLAPAESRDDLEQVAARYAIAVTPDVAALIDPNDPHDPIARQYIPRADELVTLPIE
RDDPIGDGAHAPVEGIVHRHRDRVLLKLVHVCAVYCRFCFRRETIGPGKDNALSREATAAALDYIRAHPEIWEVIFTGGD
PLMLSPRRMAEIMAELATIAHVKIIRFHTRVPVADPARITPELVRALQTPGKTTWVALHANHPRELTAAARAACAMLIDA
GIPMVSQSVLLRGVNDDSETLEALMRGFVECRIKPYYLHHGDLAPGTAHLRTTIAEGQALMRALRGRVSGLCQPEYVLDI
PGGYGKAPIGPNYLTGEDGTVADSRYRVRDYCGDVHLYPPGSC
>Mature_362_residues
SRVTRLQTPAATTLRQPSELIAQGLAPAESRDDLEQVAARYAIAVTPDVAALIDPNDPHDPIARQYIPRADELVTLPIER
DDPIGDGAHAPVEGIVHRHRDRVLLKLVHVCAVYCRFCFRRETIGPGKDNALSREATAAALDYIRAHPEIWEVIFTGGDP
LMLSPRRMAEIMAELATIAHVKIIRFHTRVPVADPARITPELVRALQTPGKTTWVALHANHPRELTAAARAACAMLIDAG
IPMVSQSVLLRGVNDDSETLEALMRGFVECRIKPYYLHHGDLAPGTAHLRTTIAEGQALMRALRGRVSGLCQPEYVLDIP
GGYGKAPIGPNYLTGEDGTVADSRYRVRDYCGDVHLYPPGSC

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=338, Percent_Identity=34.0236686390533, Blast_Score=191, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 39749; Mature: 39618

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVTRLQTPAATTLRQPSELIAQGLAPAESRDDLEQVAARYAIAVTPDVAALIDPNDPH
CCCCCCCCCCHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCEEEEECCCCCC
DPIARQYIPRADELVTLPIERDDPIGDGAHAPVEGIVHRHRDRVLLKLVHVCAVYCRFCF
CHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRETIGPGKDNALSREATAAALDYIRAHPEIWEVIFTGGDPLMLSPRRMAEIMAELATIA
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHH
HVKIIRFHTRVPVADPARITPELVRALQTPGKTTWVALHANHPRELTAAARAACAMLIDA
HHHEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHC
GIPMVSQSVLLRGVNDDSETLEALMRGFVECRIKPYYLHHGDLAPGTAHLRTTIAEGQAL
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
MRALRGRVSGLCQPEYVLDIPGGYGKAPIGPNYLTGEDGTVADSRYRVRDYCGDVHLYPP
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHCCCEEECCC
GSC
CCC
>Mature Secondary Structure 
SRVTRLQTPAATTLRQPSELIAQGLAPAESRDDLEQVAARYAIAVTPDVAALIDPNDPH
CCCCCCCCCHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCEEEEECCCCCC
DPIARQYIPRADELVTLPIERDDPIGDGAHAPVEGIVHRHRDRVLLKLVHVCAVYCRFCF
CHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRETIGPGKDNALSREATAAALDYIRAHPEIWEVIFTGGDPLMLSPRRMAEIMAELATIA
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHH
HVKIIRFHTRVPVADPARITPELVRALQTPGKTTWVALHANHPRELTAAARAACAMLIDA
HHHEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHC
GIPMVSQSVLLRGVNDDSETLEALMRGFVECRIKPYYLHHGDLAPGTAHLRTTIAEGQAL
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHH
MRALRGRVSGLCQPEYVLDIPGGYGKAPIGPNYLTGEDGTVADSRYRVRDYCGDVHLYPP
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHCCCEEECCC
GSC
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]