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The map label for this gene is fbp [H]

Identifier: 86750046

GI number: 86750046

Start: 3341732

End: 3342196

Strand: Reverse

Name: fbp [H]

Synonym: RPB_2929

Alternate gene names: 86750046

Gene position: 3342196-3341732 (Counterclockwise)

Preceding gene: 86750048

Following gene: 86750044

Centisome position: 62.69

GC content: 66.45

Gene sequence:

>465_bases
ATGCCTTTCGCCCCCCGCGCCAGCGCCATGCTGGCCATCGCTTTCGTCGCGGCGCTGTCCGCAACCGCGACCCTGACAAT
GAGTACCCCAGCAATGTCCGAATCCGCCAAGACCGTCACCACGCCCTCCGGCCTCAAGATCGAGGATGCCACCGTCGGCA
GCGGCGCATCGCCCGCGCGCGGCCAGATCTGCGTGATGCACTACACCGGCTGGCTGTACGAGAACGGCGTCAAGGGCAAG
AAATTCGACTCCTCGGTCGATCGCAACGAGCCGTTCGAATTCCCGATCGGAATGGGCCGTGTGATCAAGGGCTGGGACGA
GGGCGTCGCCAGCATGAAGGTCGGCGGCAAGCGCACGCTGATCATTCCGCCCGAGCTCGGCTACGGCGCGCGGGGCGCCG
GCGGCGTGATTCCGCCGAATGCCACGCTGATCTTCGAGGTCGAGCTGCTCGGCGTGAAGGGCTGA

Upstream 100 bases:

>100_bases
GGCGGGCGGATGAGTTCCGCCGGGCGGTTGTGATGTGGGTCTGTTCTGTCTAGAACGGGGCCTCGCTCGCGATCGACCCG
ACCTGTCCGAGGACAATCCG

Downstream 100 bases:

>100_bases
GCGGTCGAACGGATCGTGCGGCCGCCCGCCATCGCAGGCGGCTGCACGTCGGTGGCCGGCTTATGGGCGACCGCAATAGA
CCAGGATGCTACCCGCCTTG

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MPFAPRASAMLAIAFVAALSATATLTMSTPAMSESAKTVTTPSGLKIEDATVGSGASPARGQICVMHYTGWLYENGVKGK
KFDSSVDRNEPFEFPIGMGRVIKGWDEGVASMKVGGKRTLIIPPELGYGARGAGGVIPPNATLIFEVELLGVKG

Sequences:

>Translated_154_residues
MPFAPRASAMLAIAFVAALSATATLTMSTPAMSESAKTVTTPSGLKIEDATVGSGASPARGQICVMHYTGWLYENGVKGK
KFDSSVDRNEPFEFPIGMGRVIKGWDEGVASMKVGGKRTLIIPPELGYGARGAGGVIPPNATLIFEVELLGVKG
>Mature_153_residues
PFAPRASAMLAIAFVAALSATATLTMSTPAMSESAKTVTTPSGLKIEDATVGSGASPARGQICVMHYTGWLYENGVKGKK
FDSSVDRNEPFEFPIGMGRVIKGWDEGVASMKVGGKRTLIIPPELGYGARGAGGVIPPNATLIFEVELLGVKG

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=111, Percent_Identity=53.1531531531532, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI4503725, Length=111, Percent_Identity=53.1531531531532, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI4758380, Length=111, Percent_Identity=54.0540540540541, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI206725530, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI17149844, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI17149842, Length=94, Percent_Identity=54.2553191489362, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI4503729, Length=97, Percent_Identity=50.5154639175258, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI224809329, Length=130, Percent_Identity=46.9230769230769, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI224809327, Length=130, Percent_Identity=46.9230769230769, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI4758384, Length=130, Percent_Identity=46.9230769230769, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI224809331, Length=129, Percent_Identity=44.9612403100775, Blast_Score=97, Evalue=6e-21,
Organism=Homo sapiens, GI192448443, Length=119, Percent_Identity=42.0168067226891, Blast_Score=86, Evalue=9e-18,
Organism=Homo sapiens, GI150010552, Length=107, Percent_Identity=40.1869158878505, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI8923659, Length=96, Percent_Identity=43.75, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI206725547, Length=150, Percent_Identity=34.6666666666667, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI4503727, Length=161, Percent_Identity=32.9192546583851, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI31317231, Length=151, Percent_Identity=35.0993377483444, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI33469985, Length=92, Percent_Identity=41.304347826087, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI17149839, Length=70, Percent_Identity=52.8571428571429, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI87082390, Length=147, Percent_Identity=44.8979591836735, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1789745, Length=153, Percent_Identity=39.2156862745098, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71993519, Length=97, Percent_Identity=58.7628865979381, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17540882, Length=93, Percent_Identity=52.6881720430108, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561782, Length=93, Percent_Identity=50.5376344086022, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993555, Length=68, Percent_Identity=51.4705882352941, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561778, Length=75, Percent_Identity=46.6666666666667, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324194, Length=110, Percent_Identity=52.7272727272727, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320727, Length=88, Percent_Identity=59.0909090909091, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323566, Length=111, Percent_Identity=45.045045045045, Blast_Score=84, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323482, Length=117, Percent_Identity=41.8803418803419, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363946, Length=93, Percent_Identity=59.1397849462366, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17352457, Length=93, Percent_Identity=59.1397849462366, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655568, Length=111, Percent_Identity=52.2522522522522, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24647110, Length=120, Percent_Identity=49.1666666666667, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583150, Length=98, Percent_Identity=53.0612244897959, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356629, Length=145, Percent_Identity=41.3793103448276, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16004; Mature: 15873

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFAPRASAMLAIAFVAALSATATLTMSTPAMSESAKTVTTPSGLKIEDATVGSGASPAR
CCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEECCCCCEEECCCCCCCCCCCC
GQICVMHYTGWLYENGVKGKKFDSSVDRNEPFEFPIGMGRVIKGWDEGVASMKVGGKRTL
CCEEEEEECCEEEECCCCCCCCCCCCCCCCCEECCCCCCCEECCCCCCCEEEECCCCEEE
IIPPELGYGARGAGGVIPPNATLIFEVELLGVKG
EECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure 
PFAPRASAMLAIAFVAALSATATLTMSTPAMSESAKTVTTPSGLKIEDATVGSGASPAR
CCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEECCCCCEEECCCCCCCCCCCC
GQICVMHYTGWLYENGVKGKKFDSSVDRNEPFEFPIGMGRVIKGWDEGVASMKVGGKRTL
CCEEEEEECCEEEECCCCCCCCCCCCCCCCCEECCCCCCCEECCCCCCCEEEECCCCEEE
IIPPELGYGARGAGGVIPPNATLIFEVELLGVKG
EECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]