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The map label for this gene is frr

Identifier: 86749942

GI number: 86749942

Start: 3219782

End: 3220345

Strand: Reverse

Name: frr

Synonym: RPB_2825

Alternate gene names: 86749942

Gene position: 3220345-3219782 (Counterclockwise)

Preceding gene: 86749943

Following gene: 86749941

Centisome position: 60.4

GC content: 61.88

Gene sequence:

>564_bases
ATGCAGTCCGAAAAGTTCGACATCAATGATTTGAAGCGCCGGATGCAGGGCGCGTCGCAGGCTTTGCAGCACGAACTCGG
CGGCCTGCGCACCGGCCGCGCGGCGGCTTCGATGCTGGAGCCCGTGCAGGTCGATGCCTATGGCACCCACATGCCGCTCA
ATCAGCTCGCCACCGTCACCGTGCCCGAGCCCCGCTTGCTGTCGGTGCAGGTGTGGGACAAGTCGATGGTCCGGGCGGTC
GAAAAGGCGATCGTCGACTCCAATCTCGGCCTCAGCCCGGCCACCGAGGGCCAGGTGTTGCGGCTGCGGATTCCCGAGCT
CAATCAGGATCGCCGCAAGGAACTGGTGAAGGTCGCGCACAAATACGCCGAGGCCGCCCGTGTCGCGGTCCGCCATGTTC
GCCGCGACGGCCTTGATACGATCAAGAAATTGGAGAAGTCTCACGAGATCTCCGAAGACGATCAGAAGCGGCTGGATCAG
GAAGTTCAGAAGGCGACCGATAGCGCGATTTCCGAGATCGACCAGTTGCTCGCGAGCAAGGAAAAAGAAATCCTGACCGT
CTAG

Upstream 100 bases:

>100_bases
TGCTGGGCGGCGCGGGCCGAGCGACTGTCGTCGCGGGTTGAGTTTCGCGTGCCGCGAGGCGTCGCGATGAGGATTCAGAA
TTCGAGAGGGAGTGACTGGC

Downstream 100 bases:

>100_bases
ATTTTCTGCTTCGGCGCCGCCGCGCGCGGCGCCGGGGGCGAGGCCCCAGCGGAACGCGGTCGGGCAATTTGCATACGCGG
CGACGAGAGAATCAGGCCTA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MQSEKFDINDLKRRMQGASQALQHELGGLRTGRAAASMLEPVQVDAYGTHMPLNQLATVTVPEPRLLSVQVWDKSMVRAV
EKAIVDSNLGLSPATEGQVLRLRIPELNQDRRKELVKVAHKYAEAARVAVRHVRRDGLDTIKKLEKSHEISEDDQKRLDQ
EVQKATDSAISEIDQLLASKEKEILTV

Sequences:

>Translated_187_residues
MQSEKFDINDLKRRMQGASQALQHELGGLRTGRAAASMLEPVQVDAYGTHMPLNQLATVTVPEPRLLSVQVWDKSMVRAV
EKAIVDSNLGLSPATEGQVLRLRIPELNQDRRKELVKVAHKYAEAARVAVRHVRRDGLDTIKKLEKSHEISEDDQKRLDQ
EVQKATDSAISEIDQLLASKEKEILTV
>Mature_187_residues
MQSEKFDINDLKRRMQGASQALQHELGGLRTGRAAASMLEPVQVDAYGTHMPLNQLATVTVPEPRLLSVQVWDKSMVRAV
EKAIVDSNLGLSPATEGQVLRLRIPELNQDRRKELVKVAHKYAEAARVAVRHVRRDGLDTIKKLEKSHEISEDDQKRLDQ
EVQKATDSAISEIDQLLASKEKEILTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=25.8241758241758, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI291042689, Length=176, Percent_Identity=28.9772727272727, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=47.2527472527472, Blast_Score=163, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24661488, Length=183, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_RHOP2 (Q2IW83)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486438.1
- ProteinModelPortal:   Q2IW83
- SMR:   Q2IW83
- STRING:   Q2IW83
- GeneID:   3910618
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2825
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   RPAL316058:RPB_2825-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20980; Mature: 20980

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSEKFDINDLKRRMQGASQALQHELGGLRTGRAAASMLEPVQVDAYGTHMPLNQLATVT
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHCEEEE
VPEPRLLSVQVWDKSMVRAVEKAIVDSNLGLSPATEGQVLRLRIPELNQDRRKELVKVAH
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYAEAARVAVRHVRRDGLDTIKKLEKSHEISEDDQKRLDQEVQKATDSAISEIDQLLASK
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EKEILTV
CHHHCCC
>Mature Secondary Structure
MQSEKFDINDLKRRMQGASQALQHELGGLRTGRAAASMLEPVQVDAYGTHMPLNQLATVT
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHCEEEE
VPEPRLLSVQVWDKSMVRAVEKAIVDSNLGLSPATEGQVLRLRIPELNQDRRKELVKVAH
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYAEAARVAVRHVRRDGLDTIKKLEKSHEISEDDQKRLDQEVQKATDSAISEIDQLLASK
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EKEILTV
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA