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The map label for this gene is queC1

Identifier: 86749826

GI number: 86749826

Start: 3094042

End: 3094758

Strand: Reverse

Name: queC1

Synonym: RPB_2709

Alternate gene names: 86749826

Gene position: 3094758-3094042 (Counterclockwise)

Preceding gene: 86749830

Following gene: 86749825

Centisome position: 58.04

GC content: 67.09

Gene sequence:

>717_bases
ATGACCGAACCAGTTTCCGACCAGACCGCGCTGGTGCTATTCTCCGGCGGGCAGGATTCCGCCACCTGCCTCGCCTGGGC
GCTGTCGCGCTTTGCGCGGGTCGAGATGATCGGCTTCGACTACGGCCAGCGCCACGCCGTCGAACTCGATTGCCGGGCAA
AGCTGCTCGACGGGTTTCGCGCGATCAGCAGTGAATGGGCGTCGAAGCTCGGCGACAGCCACACGCTCGCGATCCCGACG
CTCAGCGCGATCTCCGACACCGCGCTGACCCGCGACGTCGAAATCGCGATGGGGGCGGACGGCCTTCCGAACACCTTCGT
GCCCGGCCGCAACCTGATCTTTCTGACGTTTGCGGCCGCGCTGGCCTATCGCCGCGGCATCGCCGACATCGTCGGCGGGA
TGTGCGAGACCGATTACTCCGGCTATCCGGATTGTCGCGACGATACCATCAAGGCGCTGCAAGGCGCGATCAGCCTCGGC
ATGGCGCGCGACTTCGAACTGCATACGCCGCTGATGTGGCGCGACAAGGCCGCGACCTGGCAGCTCGCGCATGATCTCGG
CGGCGCGGCGCTGGTCGATCTGATCCGCGAGCACTCGCACACCTGCTATCTCGGCGAACGCGGCGAGCGGCACGATTGGG
GCTATGGCTGCGGCGAATGTCCGGCCTGCGCGTTGCGCGCCAGGGGATGGCGGGAGTATCGGACGCGGACCGGATAG

Upstream 100 bases:

>100_bases
GGCGTGAGGCGATCCGCTTCCTATGCCGCAAGAGGGCGCGGCGTCCCAGCGAAATTGCTTTGATTTGGCGGCGGCGGCGC
GCGGTGCTAGAGCGACGCGC

Downstream 100 bases:

>100_bases
CACCCAAGCCGCTGTCATCCGGATCATCTCTGCGTATGATAGCTCTTCGCCGCACCGATCGCGATTGTCGGTCGACCCAT
TGAACCGGCGAGCGAGATGC

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase 1; PreQ(0) synthase 1; Queuosine biosynthesis protein queC 1

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTEPVSDQTALVLFSGGQDSATCLAWALSRFARVEMIGFDYGQRHAVELDCRAKLLDGFRAISSEWASKLGDSHTLAIPT
LSAISDTALTRDVEIAMGADGLPNTFVPGRNLIFLTFAAALAYRRGIADIVGGMCETDYSGYPDCRDDTIKALQGAISLG
MARDFELHTPLMWRDKAATWQLAHDLGGAALVDLIREHSHTCYLGERGERHDWGYGCGECPACALRARGWREYRTRTG

Sequences:

>Translated_238_residues
MTEPVSDQTALVLFSGGQDSATCLAWALSRFARVEMIGFDYGQRHAVELDCRAKLLDGFRAISSEWASKLGDSHTLAIPT
LSAISDTALTRDVEIAMGADGLPNTFVPGRNLIFLTFAAALAYRRGIADIVGGMCETDYSGYPDCRDDTIKALQGAISLG
MARDFELHTPLMWRDKAATWQLAHDLGGAALVDLIREHSHTCYLGERGERHDWGYGCGECPACALRARGWREYRTRTG
>Mature_237_residues
TEPVSDQTALVLFSGGQDSATCLAWALSRFARVEMIGFDYGQRHAVELDCRAKLLDGFRAISSEWASKLGDSHTLAIPTL
SAISDTALTRDVEIAMGADGLPNTFVPGRNLIFLTFAAALAYRRGIADIVGGMCETDYSGYPDCRDDTIKALQGAISLGM
ARDFELHTPLMWRDKAATWQLAHDLGGAALVDLIREHSHTCYLGERGERHDWGYGCGECPACALRARGWREYRTRTG

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=232, Percent_Identity=46.9827586206897, Blast_Score=204, Evalue=5e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC1_RHOP2 (Q2IWJ9)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486322.1
- ProteinModelPortal:   Q2IWJ9
- SMR:   Q2IWJ9
- STRING:   Q2IWJ9
- GeneID:   3910502
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_2709
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK864419
- BioCyc:   RPAL316058:RPB_2709-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26067; Mature: 25936

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPVSDQTALVLFSGGQDSATCLAWALSRFARVEMIGFDYGQRHAVELDCRAKLLDGFR
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEHHHHHHHHHHHH
AISSEWASKLGDSHTLAIPTLSAISDTALTRDVEIAMGADGLPNTFVPGRNLIFLTFAAA
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LAYRRGIADIVGGMCETDYSGYPDCRDDTIKALQGAISLGMARDFELHTPLMWRDKAATW
HHHHCCHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHH
QLAHDLGGAALVDLIREHSHTCYLGERGERHDWGYGCGECPACALRARGWREYRTRTG
HHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
TEPVSDQTALVLFSGGQDSATCLAWALSRFARVEMIGFDYGQRHAVELDCRAKLLDGFR
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCCCEEEEHHHHHHHHHHHH
AISSEWASKLGDSHTLAIPTLSAISDTALTRDVEIAMGADGLPNTFVPGRNLIFLTFAAA
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LAYRRGIADIVGGMCETDYSGYPDCRDDTIKALQGAISLGMARDFELHTPLMWRDKAATW
HHHHCCHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHH
QLAHDLGGAALVDLIREHSHTCYLGERGERHDWGYGCGECPACALRARGWREYRTRTG
HHHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA