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The map label for this gene is fadB1 [H]

Identifier: 86749786

GI number: 86749786

Start: 3052035

End: 3052862

Strand: Reverse

Name: fadB1 [H]

Synonym: RPB_2669

Alternate gene names: 86749786

Gene position: 3052862-3052035 (Counterclockwise)

Preceding gene: 86749792

Following gene: 86749785

Centisome position: 57.26

GC content: 66.79

Gene sequence:

>828_bases
ATGACTGCCCTGCCCGCCTCTACGGCGAATTCTCCGTCGCCGATCCTGTTGCGCGAGACGATCGACGGCGGTGTCGCGGT
GCTGACGCTGAATCGTCCGGCCGCGCGCAACAGCCTGTCGCTGGAACTGATTGCGGATTTGCACGCCGCGCTCGATCTGA
TCGGCCGCGACGACGGCGTGCGCGCCGTGGTGATCGCCGCCAACGGGCCTGTGTTCTCGGCCGGCCACGACATGAAGGAA
CTGACCGCCCATCGCAACGATGCCGACCGCGGCCGCGCCAGCTTCAACCGGATCATGACCGCGTGCAGCGCAATGATGCA
GACCATCGTGTTGCTGCCGAAGCCGGTGATCGCGGCGGTGCAAGGCGTCGCCACCGCCGCCGGCTGCCAGCTGGTCGCGA
GCTGCGATCTCGCGGTCGCCTCCGAGCGGGCGACCTTCGCGACGCCCGGCGTCGACATCGGCCTGTTCTGTTCGACGCCG
ATGGTGGCGCTGACCCGCAACGTGCCGCGCAAGCACGCGATGCACATGCTGCTGACAGGCGAACCGGTGAAGGCCGACGA
AGCCCGCGCGATCGGATTGATCAATCGCGTCGTCCCCCACGGCACCGAACGCGATGCCGCGATCGCCCTCGCCGAAACCA
TCGCGAGCAAGTCGTCGCACACCGTCAAGATCGGCAAGGAAGCGTTCTATCGTCAGGCCGAGCTGAATCTCGCCGACGCC
TATCACTACGCCTCGCAGGTCATGGCCGAGAACATGATGGCCGCCGACGCCGAAGAAGGCATCGGCGCCTTCCTCGACAA
GCGCAAGCCGGAGTGGAAGGATCGCTAG

Upstream 100 bases:

>100_bases
GCATGTGTCATGTGTTCCCGCCCTGCTCTCGTTTTCGCCGGGTTTGTTACAATAACGTGACGTCCGTTCCCAGCGCTGGA
TTCTTGTTCCGGAAGGTTTC

Downstream 100 bases:

>100_bases
TCACTTCGAGGCAGCCCCGTCATTGCGAGCGAAGCGAAGCAATCCAGGGCCACGCCATCGAAGCTGGATTGCTTCGTCGC
TTCGCTCCTCGCAATGACGG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTALPASTANSPSPILLRETIDGGVAVLTLNRPAARNSLSLELIADLHAALDLIGRDDGVRAVVIAANGPVFSAGHDMKE
LTAHRNDADRGRASFNRIMTACSAMMQTIVLLPKPVIAAVQGVATAAGCQLVASCDLAVASERATFATPGVDIGLFCSTP
MVALTRNVPRKHAMHMLLTGEPVKADEARAIGLINRVVPHGTERDAAIALAETIASKSSHTVKIGKEAFYRQAELNLADA
YHYASQVMAENMMAADAEEGIGAFLDKRKPEWKDR

Sequences:

>Translated_275_residues
MTALPASTANSPSPILLRETIDGGVAVLTLNRPAARNSLSLELIADLHAALDLIGRDDGVRAVVIAANGPVFSAGHDMKE
LTAHRNDADRGRASFNRIMTACSAMMQTIVLLPKPVIAAVQGVATAAGCQLVASCDLAVASERATFATPGVDIGLFCSTP
MVALTRNVPRKHAMHMLLTGEPVKADEARAIGLINRVVPHGTERDAAIALAETIASKSSHTVKIGKEAFYRQAELNLADA
YHYASQVMAENMMAADAEEGIGAFLDKRKPEWKDR
>Mature_274_residues
TALPASTANSPSPILLRETIDGGVAVLTLNRPAARNSLSLELIADLHAALDLIGRDDGVRAVVIAANGPVFSAGHDMKEL
TAHRNDADRGRASFNRIMTACSAMMQTIVLLPKPVIAAVQGVATAAGCQLVASCDLAVASERATFATPGVDIGLFCSTPM
VALTRNVPRKHAMHMLLTGEPVKADEARAIGLINRVVPHGTERDAAIALAETIASKSSHTVKIGKEAFYRQAELNLADAY
HYASQVMAENMMAADAEEGIGAFLDKRKPEWKDR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=263, Percent_Identity=46.7680608365019, Blast_Score=237, Evalue=7e-63,
Organism=Homo sapiens, GI194097323, Length=274, Percent_Identity=33.5766423357664, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI4502327, Length=259, Percent_Identity=28.957528957529, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI70995211, Length=224, Percent_Identity=30.8035714285714, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260274832, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI45643119, Length=253, Percent_Identity=24.5059288537549, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI260275230, Length=253, Percent_Identity=24.5059288537549, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI4757968, Length=270, Percent_Identity=26.2962962962963, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI49355787, Length=270, Percent_Identity=26.2962962962963, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI221307494, Length=261, Percent_Identity=26.8199233716475, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI25453481, Length=255, Percent_Identity=26.2745098039216, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI51538573, Length=255, Percent_Identity=26.2745098039216, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4757966, Length=185, Percent_Identity=30.8108108108108, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI51538581, Length=185, Percent_Identity=30.8108108108108, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI20127408, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI116235487, Length=188, Percent_Identity=29.2553191489362, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=34.5238095238095, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=30.4511278195489, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082183, Length=253, Percent_Identity=28.4584980237154, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=33.206106870229, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=24.9027237354086, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790281, Length=187, Percent_Identity=24.0641711229947, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540306, Length=267, Percent_Identity=43.8202247191011, Blast_Score=212, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17554946, Length=255, Percent_Identity=34.9019607843137, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=32.1428571428571, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=286, Percent_Identity=26.2237762237762, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=256, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=252, Percent_Identity=26.5873015873016, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=29.3838862559242, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=218, Percent_Identity=27.0642201834862, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=196, Percent_Identity=26.0204081632653, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922422, Length=270, Percent_Identity=39.6296296296296, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI20129971, Length=273, Percent_Identity=31.5018315018315, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653477, Length=273, Percent_Identity=31.5018315018315, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653139, Length=270, Percent_Identity=29.6296296296296, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19920382, Length=282, Percent_Identity=26.9503546099291, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357171, Length=270, Percent_Identity=27.037037037037, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24650670, Length=262, Percent_Identity=29.3893129770992, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24583165, Length=215, Percent_Identity=28.3720930232558, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24654903, Length=180, Percent_Identity=29.4444444444444, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19921018, Length=181, Percent_Identity=27.0718232044199, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29131; Mature: 29000

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALPASTANSPSPILLRETIDGGVAVLTLNRPAARNSLSLELIADLHAALDLIGRDDGV
CCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
RAVVIAANGPVFSAGHDMKELTAHRNDADRGRASFNRIMTACSAMMQTIVLLPKPVIAAV
EEEEEEECCCEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QGVATAAGCQLVASCDLAVASERATFATPGVDIGLFCSTPMVALTRNVPRKHAMHMLLTG
HHHHHHHHHHHEECCCHHHHCCCCEEECCCCCEEEECCCCHHHHHCCCCHHHHEEEEECC
EPVKADEARAIGLINRVVPHGTERDAAIALAETIASKSSHTVKIGKEAFYRQAELNLADA
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCHHHH
YHYASQVMAENMMAADAEEGIGAFLDKRKPEWKDR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TALPASTANSPSPILLRETIDGGVAVLTLNRPAARNSLSLELIADLHAALDLIGRDDGV
CCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
RAVVIAANGPVFSAGHDMKELTAHRNDADRGRASFNRIMTACSAMMQTIVLLPKPVIAAV
EEEEEEECCCEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QGVATAAGCQLVASCDLAVASERATFATPGVDIGLFCSTPMVALTRNVPRKHAMHMLLTG
HHHHHHHHHHHEECCCHHHHCCCCEEECCCCCEEEECCCCHHHHHCCCCHHHHEEEEECC
EPVKADEARAIGLINRVVPHGTERDAAIALAETIASKSSHTVKIGKEAFYRQAELNLADA
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCHHHH
YHYASQVMAENMMAADAEEGIGAFLDKRKPEWKDR
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]