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The map label for this gene is yfhM [H]

Identifier: 86749762

GI number: 86749762

Start: 3025362

End: 3026231

Strand: Direct

Name: yfhM [H]

Synonym: RPB_2645

Alternate gene names: 86749762

Gene position: 3025362-3026231 (Clockwise)

Preceding gene: 86749761

Following gene: 86749764

Centisome position: 56.74

GC content: 68.39

Gene sequence:

>870_bases
GTGGTGACGCCGATCCGATCCAGGACGCTCGAGGCAAACGGTCTCGGCTTCGCGATCGACGAAGCCGGCGAGGGCGACAC
CACGGCGCTGTTGTTGCACGGCTTCCCGGAAGCGCGCCAGTCGTGGCATCGGCAACTCCCGGCGCTGGCCGCGCTCGGCT
GGCATGCGGTCGCGCCGGATCTGCGCGGCTATGGGGGAACGACGCGGCCTCGGGCGCAGGCGGCCTATCATCTCGATCAC
CTCACCGACGACGTCGCGGCATTGTTCGCGGCGCTCGGCGGCAAGCGCCGGATTCTGATCGGCCACGATTGGGGCGGGGT
GATCGCCTGGCAGGCTGCGCTGCGCGGCAAGCTGCCGCTCGACGCCCTGATTATCCTCAACGCACCGCATCCGGACGTGT
TCGCGCGCGTGCTGGCCGATGGCTGGCGGCAGAAGCGCAAGTCCTGGTATGTCGCGTTGTTCCAGCTGCCCTGGCTGCCG
GAATGGCTGATGACCCGCAACGACGGCGCAGCGCTGGCGCAGATGTTTCGCAAGCACAGCCCGACGATCTCGGACGCGCA
GATCGAGATCTATCGCCGCAACGCGATCCAGCCCGGTGCGGCGATCGCGATGATCAATTACTACCGCGCCAATTTCACCG
CGCTCGGCGGCGGCGCAGGGACCCATCCCAAGCTGACCGTGCCGACCCTGATGATCTGGGGGGAGGACGATCTGGCGCTC
GATATCGCGCTGACAGAGGGCAACGAGGCCCATGTCGCCGACTTCACGCTGCGGCGGCTGCCCGGCGCCTCGCATTGGGT
GCAGCAGGACGCGCCGGATCAGGTCAACGCCCTGATCGCGGACTGGGCGCGCGGCAAGGGGCTGGCTTAG

Upstream 100 bases:

>100_bases
AGGAGGCGATCGAACTGCTGTCGAAGGCGATCCTCGAACTCGCGAGTTCGATCGAGGCGACCGACGCCAAGATCAAGAAG
ATCAACAAGGCGGGCTGATC

Downstream 100 bases:

>100_bases
CGCAGGCCGGCCGCGGCCGCCCCGCGCGATGTGATCAGCGGAAGCTGATCAGCCTGAACAGCGGCGCCAGATAGCTCATT
TCCTGGCCCGAGGTCGGCGT

Product: Alpha/beta hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MVTPIRSRTLEANGLGFAIDEAGEGDTTALLLHGFPEARQSWHRQLPALAALGWHAVAPDLRGYGGTTRPRAQAAYHLDH
LTDDVAALFAALGGKRRILIGHDWGGVIAWQAALRGKLPLDALIILNAPHPDVFARVLADGWRQKRKSWYVALFQLPWLP
EWLMTRNDGAALAQMFRKHSPTISDAQIEIYRRNAIQPGAAIAMINYYRANFTALGGGAGTHPKLTVPTLMIWGEDDLAL
DIALTEGNEAHVADFTLRRLPGASHWVQQDAPDQVNALIADWARGKGLA

Sequences:

>Translated_289_residues
MVTPIRSRTLEANGLGFAIDEAGEGDTTALLLHGFPEARQSWHRQLPALAALGWHAVAPDLRGYGGTTRPRAQAAYHLDH
LTDDVAALFAALGGKRRILIGHDWGGVIAWQAALRGKLPLDALIILNAPHPDVFARVLADGWRQKRKSWYVALFQLPWLP
EWLMTRNDGAALAQMFRKHSPTISDAQIEIYRRNAIQPGAAIAMINYYRANFTALGGGAGTHPKLTVPTLMIWGEDDLAL
DIALTEGNEAHVADFTLRRLPGASHWVQQDAPDQVNALIADWARGKGLA
>Mature_289_residues
MVTPIRSRTLEANGLGFAIDEAGEGDTTALLLHGFPEARQSWHRQLPALAALGWHAVAPDLRGYGGTTRPRAQAAYHLDH
LTDDVAALFAALGGKRRILIGHDWGGVIAWQAALRGKLPLDALIILNAPHPDVFARVLADGWRQKRKSWYVALFQLPWLP
EWLMTRNDGAALAQMFRKHSPTISDAQIEIYRRNAIQPGAAIAMINYYRANFTALGGGAGTHPKLTVPTLMIWGEDDLAL
DIALTEGNEAHVADFTLRRLPGASHWVQQDAPDQVNALIADWARGKGLA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=279, Percent_Identity=40.1433691756272, Blast_Score=193, Evalue=1e-49,
Organism=Homo sapiens, GI218777840, Length=281, Percent_Identity=32.3843416370107, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI13376164, Length=281, Percent_Identity=32.3843416370107, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI27597073, Length=295, Percent_Identity=25.7627118644068, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI145611434, Length=268, Percent_Identity=23.5074626865672, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=284, Percent_Identity=34.5070422535211, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17562298, Length=272, Percent_Identity=34.9264705882353, Blast_Score=160, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 31628; Mature: 31628

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTPIRSRTLEANGLGFAIDEAGEGDTTALLLHGFPEARQSWHRQLPALAALGWHAVAPD
CCCCCCCCEEECCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHCHHHHHHCCHHCCCC
LRGYGGTTRPRAQAAYHLDHLTDDVAALFAALGGKRRILIGHDWGGVIAWQAALRGKLPL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCE
DALIILNAPHPDVFARVLADGWRQKRKSWYVALFQLPWLPEWLMTRNDGAALAQMFRKHS
EEEEEEECCCHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHCCCCCHHHHHHHHHCC
PTISDAQIEIYRRNAIQPGAAIAMINYYRANFTALGGGAGTHPKLTVPTLMIWGEDDLAL
CCCCCCEEEEEECCCCCCCCEEEEEEEEECCEEEECCCCCCCCCEEEEEEEEECCCCEEE
DIALTEGNEAHVADFTLRRLPGASHWVQQDAPDQVNALIADWARGKGLA
EEEEECCCCCEEHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVTPIRSRTLEANGLGFAIDEAGEGDTTALLLHGFPEARQSWHRQLPALAALGWHAVAPD
CCCCCCCCEEECCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHCHHHHHHCCHHCCCC
LRGYGGTTRPRAQAAYHLDHLTDDVAALFAALGGKRRILIGHDWGGVIAWQAALRGKLPL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCE
DALIILNAPHPDVFARVLADGWRQKRKSWYVALFQLPWLPEWLMTRNDGAALAQMFRKHS
EEEEEEECCCHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHCCCCCHHHHHHHHHCC
PTISDAQIEIYRRNAIQPGAAIAMINYYRANFTALGGGAGTHPKLTVPTLMIWGEDDLAL
CCCCCCEEEEEECCCCCCCCEEEEEEEEECCEEEECCCCCCCCCEEEEEEEEECCCCEEE
DIALTEGNEAHVADFTLRRLPGASHWVQQDAPDQVNALIADWARGKGLA
EEEEECCCCCEEHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]