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The map label for this gene is mcp4 [H]

Identifier: 86749370

GI number: 86749370

Start: 2596295

End: 2598307

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_2250

Alternate gene names: 86749370

Gene position: 2596295-2598307 (Clockwise)

Preceding gene: 86749369

Following gene: 86749372

Centisome position: 48.7

GC content: 64.93

Gene sequence:

>2013_bases
ATGCTCAAGCTCAATCGAATCGGAAACAAACTCGGAATCGCCGGCCTGATCGGTATTTCTCTCGCGATCGGCATGGTGGT
CAACCAGTCCATCACCGAATCGAAGGTGAAGGAGGCGACGCGGATCGCCGATGTTGAGGCGCAGGTTTCGGAGAAGGCGC
TGATCGCCGAGTCGGAAATGCGCAACATGCAGCTCGCCGTGCGCGGCGTGCGGCTCTCGCGATCGCTCAAGGAACTCGAT
CAGCGCACGAGCCAATTCAATGAGGCCCGGGATTCCCAGGTCAAGCTGCTGGATGCCGCCATCTCGCTCGCGATTCTGCC
GGGCGACAAGGACATGTTCACCGAACTCAAGAAGATGAACATCGAATATGCCGCCGGAGCCGGCGAGCAGGCCGAGCAGC
ATCGCCGAGGCCTTGATCTCAACCTCAAACGTGCGTCATTGGCCACCGAGTGGGACAAGAAGGTCGCGGCGCTGAAACCG
GTGCTCGGCCCCGGTGCGGCGCTCGGAAATCTGCGCGAGGCGGACGGGGATTTCGCCGCCATCCGCTCGATCGGCTGGAA
GTACTTCGTCGTCGACGAGAAAGACTACAAGGCCAAGATGGACGGGAAGATTTCGGAATCAGCCGAGAGTCTGAAGCGCG
CCGCCGAGCAGGCGACGGACGCCGGTTCCAAGGCTGCGCTGCGCGACCTCGAGGGCCTGCTCGCGACCTATGCCAAGACG
ACGAGCGAAGCATTTGCTGCCGATACGTTGAAGAACAGCATCAGTCGCGACCGGACTGTTCCGATCGCCAACAAAGCCGC
AAAGATGCTGCGCGGGGCGGTGGAGAAGTCGCAACAATCGGTGGCGGAAGCCAAGGCGCGGACGGCTGCGGAGATCGGCT
GGTCGGGGCGGCTCAATCTCGCTTTCGGCGCTGCGATCATTCTGGTGCTGATCGGCTCCGCATTGTTCTCGTTCCTCGGC
GTGGCCCGGCCCTTGACGCGGTTGAACGGCGCGCTCGGCGAGATCGCGGCGGGACGGCTTGACGTGAAGATCGTCGGCGC
GGAACGCGGCGACGAGATCGGCGACATCGGCAAGACCGTGGGCGTGATCCAGGCCAACGCGGAACAGAAAGCCCGCGACG
AAGTCGCGGCCAAGGCCGAGCTCGACCGCGAGCTCGCCCAGAAGCGCAAGCAGGACATGATCCGGCTCGCCGACGAATTC
GAAGGCGCGATCGGCGAGATCGTGGACACGGTGTCCGCGGCCTCGGAAGAATTGGAAGCGTCCGCCACGTCGTTGACCAC
GACCGCGGAGCGGTCGCAGTCGCTCGCCACCACGGTGGCGTCGGCATCGGAAGAGGCCTCGACCAACGTTCAGTCGGTGG
CGTCGGCGACCGAGGAAATGAGTTCTTCGGTCAATGAGATCAGCCGCCAGGTGCAGGAGTCGGCGCGGATCGCCCAGGAG
GCGGTGGATCAGGCCCGATTGACCAACGACCGGGTCGAAGAGCTGGCTCAGGCCGCTGCACGGATCGGCGACGTTGTCGA
ACTGATCAACACCATCGCCGGGCAGACCAATCTGCTGGCGCTCAACGCTACCATCGAGGCGGCGCGTGCCGGCGAGGCCG
GCCGCGGCTTCGCCGTCGTCGCCAGCGAGGTGAAAGCGCTCGCCGAGCAGACCGCCAAGGCGACCGGCGAGATCAGCCAG
CAGATCAACGGCATCCAGTCCGCGACCGAGCAGTCGGTCGCCGCCATCAAGGAGATCGGCGGAACGATCGGGCGAATGTC
GGAGATCTCGTCGACGATCGCTTCGGCGGTCGAGGAGCAGGGCGCCGCGACTCAGGAGATCTCACGCAACGTCCAGCAGG
CCGCCTACGGCACGCAGCAAGTGTCGGCGAACATCACCGACGTGCAGCGCGGCGCGACCGAGACCGGCGCCGCGTCGTCC
CAGGTGCTGCACGCCGCACAATCGCTCTCCGGCGACAGCAACCGTCTCAAGCTCGAAGTCGAGCGGTTCCTCGGAACGGT
ACGCGCCGCCTAG

Upstream 100 bases:

>100_bases
GGGCCCTGAACTTTCGGCTATCCGTAGTCCTACCAGTTCCAGCGTTAACGAGCTACTTAGAGCGCCGCTCTATCTTTTGC
GACATCAAAGGATGGTCGCA

Downstream 100 bases:

>100_bases
GGCGCCGCGCGCCGTCATCCCACCTTGGACAGCGTCCACTGCGCGAGCAGGCCGCCCAGCGCGCCTGCGAGCGCGGTGAG
CGTTGCGCCCCAGGCGATAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MLKLNRIGNKLGIAGLIGISLAIGMVVNQSITESKVKEATRIADVEAQVSEKALIAESEMRNMQLAVRGVRLSRSLKELD
QRTSQFNEARDSQVKLLDAAISLAILPGDKDMFTELKKMNIEYAAGAGEQAEQHRRGLDLNLKRASLATEWDKKVAALKP
VLGPGAALGNLREADGDFAAIRSIGWKYFVVDEKDYKAKMDGKISESAESLKRAAEQATDAGSKAALRDLEGLLATYAKT
TSEAFAADTLKNSISRDRTVPIANKAAKMLRGAVEKSQQSVAEAKARTAAEIGWSGRLNLAFGAAIILVLIGSALFSFLG
VARPLTRLNGALGEIAAGRLDVKIVGAERGDEIGDIGKTVGVIQANAEQKARDEVAAKAELDRELAQKRKQDMIRLADEF
EGAIGEIVDTVSAASEELEASATSLTTTAERSQSLATTVASASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAQE
AVDQARLTNDRVEELAQAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISQ
QINGIQSATEQSVAAIKEIGGTIGRMSEISSTIASAVEEQGAATQEISRNVQQAAYGTQQVSANITDVQRGATETGAASS
QVLHAAQSLSGDSNRLKLEVERFLGTVRAA

Sequences:

>Translated_670_residues
MLKLNRIGNKLGIAGLIGISLAIGMVVNQSITESKVKEATRIADVEAQVSEKALIAESEMRNMQLAVRGVRLSRSLKELD
QRTSQFNEARDSQVKLLDAAISLAILPGDKDMFTELKKMNIEYAAGAGEQAEQHRRGLDLNLKRASLATEWDKKVAALKP
VLGPGAALGNLREADGDFAAIRSIGWKYFVVDEKDYKAKMDGKISESAESLKRAAEQATDAGSKAALRDLEGLLATYAKT
TSEAFAADTLKNSISRDRTVPIANKAAKMLRGAVEKSQQSVAEAKARTAAEIGWSGRLNLAFGAAIILVLIGSALFSFLG
VARPLTRLNGALGEIAAGRLDVKIVGAERGDEIGDIGKTVGVIQANAEQKARDEVAAKAELDRELAQKRKQDMIRLADEF
EGAIGEIVDTVSAASEELEASATSLTTTAERSQSLATTVASASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAQE
AVDQARLTNDRVEELAQAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISQ
QINGIQSATEQSVAAIKEIGGTIGRMSEISSTIASAVEEQGAATQEISRNVQQAAYGTQQVSANITDVQRGATETGAASS
QVLHAAQSLSGDSNRLKLEVERFLGTVRAA
>Mature_670_residues
MLKLNRIGNKLGIAGLIGISLAIGMVVNQSITESKVKEATRIADVEAQVSEKALIAESEMRNMQLAVRGVRLSRSLKELD
QRTSQFNEARDSQVKLLDAAISLAILPGDKDMFTELKKMNIEYAAGAGEQAEQHRRGLDLNLKRASLATEWDKKVAALKP
VLGPGAALGNLREADGDFAAIRSIGWKYFVVDEKDYKAKMDGKISESAESLKRAAEQATDAGSKAALRDLEGLLATYAKT
TSEAFAADTLKNSISRDRTVPIANKAAKMLRGAVEKSQQSVAEAKARTAAEIGWSGRLNLAFGAAIILVLIGSALFSFLG
VARPLTRLNGALGEIAAGRLDVKIVGAERGDEIGDIGKTVGVIQANAEQKARDEVAAKAELDRELAQKRKQDMIRLADEF
EGAIGEIVDTVSAASEELEASATSLTTTAERSQSLATTVASASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAQE
AVDQARLTNDRVEELAQAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEISQ
QINGIQSATEQSVAAIKEIGGTIGRMSEISSTIASAVEEQGAATQEISRNVQQAAYGTQQVSANITDVQRGATETGAASS
QVLHAAQSLSGDSNRLKLEVERFLGTVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=355, Percent_Identity=30.7042253521127, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1788195, Length=198, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787690, Length=370, Percent_Identity=28.3783783783784, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI2367378, Length=247, Percent_Identity=30.3643724696356, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=205, Percent_Identity=30.2439024390244, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70702; Mature: 70702

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLNRIGNKLGIAGLIGISLAIGMVVNQSITESKVKEATRIADVEAQVSEKALIAESEM
CCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNMQLAVRGVRLSRSLKELDQRTSQFNEARDSQVKLLDAAISLAILPGDKDMFTELKKMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCC
IEYAAGAGEQAEQHRRGLDLNLKRASLATEWDKKVAALKPVLGPGAALGNLREADGDFAA
CHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHCCCHHHH
IRSIGWKYFVVDEKDYKAKMDGKISESAESLKRAAEQATDAGSKAALRDLEGLLATYAKT
HHHCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TSEAFAADTLKNSISRDRTVPIANKAAKMLRGAVEKSQQSVAEAKARTAAEIGWSGRLNL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AFGAAIILVLIGSALFSFLGVARPLTRLNGALGEIAAGRLDVKIVGAERGDEIGDIGKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
GVIQANAEQKARDEVAAKAELDRELAQKRKQDMIRLADEFEGAIGEIVDTVSAASEELEA
HHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATSLTTTAERSQSLATTVASASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDQARLTNDRVEELAQAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHH
ASEVKALAEQTAKATGEISQQINGIQSATEQSVAAIKEIGGTIGRMSEISSTIASAVEEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAATQEISRNVQQAAYGTQQVSANITDVQRGATETGAASSQVLHAAQSLSGDSNRLKLEV
CCHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEH
ERFLGTVRAA
HHHHHHHCCC
>Mature Secondary Structure
MLKLNRIGNKLGIAGLIGISLAIGMVVNQSITESKVKEATRIADVEAQVSEKALIAESEM
CCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNMQLAVRGVRLSRSLKELDQRTSQFNEARDSQVKLLDAAISLAILPGDKDMFTELKKMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCC
IEYAAGAGEQAEQHRRGLDLNLKRASLATEWDKKVAALKPVLGPGAALGNLREADGDFAA
CHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHCCCHHHH
IRSIGWKYFVVDEKDYKAKMDGKISESAESLKRAAEQATDAGSKAALRDLEGLLATYAKT
HHHCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TSEAFAADTLKNSISRDRTVPIANKAAKMLRGAVEKSQQSVAEAKARTAAEIGWSGRLNL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AFGAAIILVLIGSALFSFLGVARPLTRLNGALGEIAAGRLDVKIVGAERGDEIGDIGKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHH
GVIQANAEQKARDEVAAKAELDRELAQKRKQDMIRLADEFEGAIGEIVDTVSAASEELEA
HHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATSLTTTAERSQSLATTVASASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDQARLTNDRVEELAQAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHH
ASEVKALAEQTAKATGEISQQINGIQSATEQSVAAIKEIGGTIGRMSEISSTIASAVEEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAATQEISRNVQQAAYGTQQVSANITDVQRGATETGAASSQVLHAAQSLSGDSNRLKLEV
CCHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEH
ERFLGTVRAA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]