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The map label for this gene is tolQ [H]

Identifier: 86749340

GI number: 86749340

Start: 2533695

End: 2535710

Strand: Direct

Name: tolQ [H]

Synonym: RPB_2220

Alternate gene names: 86749340

Gene position: 2533695-2535710 (Clockwise)

Preceding gene: 86749339

Following gene: 86749341

Centisome position: 47.52

GC content: 66.22

Gene sequence:

>2016_bases
ATGACAATCGAGAAAGACGACGTGCGCGGCGCCGGACGGAGGTGGTCGCGAGGCACCAAGGCTTTGACCAAAGTCGGCTT
GCTTGCTGCGCTCGCCGGCATGTTGCTGAGCGCGACGCCGGCGAACGCGTGGTGGAACGACGATTGGCAACTGCGCAAGA
AGATCACGATCGATACCAGCGCCGCCGGCGCCAACATCACGGATCCAATCGGCACCACGCCGGTTCTGGTCCGTTTGCAC
AGCGGCAACTTCCGCTTCAATACCACCAAGGAAGACGGCAGTGATCTGCGCTTCGTTGCCGGCGACGACAAGACTCCGCT
GAAGTATCACGTCGAGAAATTCGACGCGCTGCTCGGCGAAGCGTTGGTCTGGGTCTCCGTTCCTGATCTGCAGCCGGGCG
CCAAGACCGATTTGTGGCTGTACTACGGCAACAAGAAGGCGGCGGCGACCGCGGATTCGAAGGGCACCTACGACGCCGAC
ACCCAGCTCGTCTATCACTTCAGCGAGCGCGGCACCGTGCCGCTCGACTCGACCGTCTGGGCCAACAACGCACAGAGCGT
CGGCCAACCCGCCGAAGGAGCTATCATCGGCACGGGCTTGCGCCTCGACGGGCGTGCGCCGCTGACCCTGCCGTCATCGT
CGGCGCTGGCGCTGGCCGGTAGCGGCGGCTGGACTTGGTCGGCCTGGGTAAAGCCGGCGTCGTCGCAGCCCAACACCGCT
TTGTACAGCCGGCGCGACGGTGGCAACGCGGTGGTGATCGGTCTGGACAACGGCGCGCCGTTCGTCGAGGTCGCCAATGC
GGGCGCAGTTCAGCGCACCGCGACGGCCGCGCCGGTCGCGCCCAACAGCTGGCATCATGTCGCTGTCGTCGCCGGCAATG
GCCGGGTTACGCTGTATCTCGACGGCAACGCTTATGCCGTCCTCGACGCCGCTCTTCCGGCGCTCAACACCCTTGCTTTC
GTCGGTGGGGACGCACTTGCCTCCAGCGCGCCTCCAACAGCGACGCCTGCCCAAACTTCGGTGCCGCTGGCCGACGAAAG
CACTCCTCCGAGCGCGGCGACGGGCGATGCACCCGCGGCCGATGCCGCGGTGGCCGCCGCCCCGGCGGCGATGGCCGGGT
TCACCGGAGATATCGACGAACTCGAAATCAGCAAGGTGTCTCGACCGGCCGGGTTCGTCCGTGTCGCGGCGATCGGCCAG
GGGCTCGACAAGGGCAAGTTGCTGGCGTTCAGCGTCGACGAAGAGTCCGGCAGCTGGTTGTCGGGATATTTCGCCGTGAT
CCTGAAATCGGTGACCCTCGACGGTTGGGTGGTGATCGCCATCCTGATGGTGATGGCGGTGATCAGCTGGATGGTGATGG
TCGACCGTGCGTCGTATCTGCGGCGTCAGGCCCGGGCCAATGCGCGGTTCATGGCTTGCTACAATGCCGTCGATTTCGAC
CTCCGGTTGCTGGGCTACGGCTCGCCGGAAGACGTGGCGACGCTCGGAGGGCGGCTCGACAACAAGGACGCAGCGCTGAT
GCGGTCGTCGTCGTTGTACCGAATCTACCATATCGCCGCCGACGAGATCCGGCGTCGGTCGGGGCAGGGCGGCGTGCCGA
CACTCTCCTCGAACTCGGTCGCGGCGATGCGGGCGGCGCTCGACGGCGGCGTGGTTCGTGAATCGCAGCGCCTCAACCGG
TTGATGGTGATGCTGACCATCGCGATTTCCGGCGGTCCGTTCCTCGGTCTGCTCGGCACCGTGGTGGGCGTGATGATCAC
CTTCGCGGCAATCGCCGCTTCCGGCGACGTCAACGTCAACGCCATCGCACCCGGCATCGCCGCCGCGCTGGTCGCCACCG
TCGCCGGCCTCGGCGTCGCCATCCCCGCGCTGTTCGGCTACAACTACCTGATCTCCCAGATCAAGAACCTGACCGCCGAC
GTCCAGGTGTTCGTCGACGACGTGGTGACGCGCATCGCCGAACTCTACACCTCAGACCTGCCGGCGCCGCTGCGCCGCGA
TCAGGCGGCGGAGTAA

Upstream 100 bases:

>100_bases
CGATTAACGGGGTCGTCGTGCTGTCGGTGCCGATGAAGGACCAAGCCTACACCCGCGCGGGTGATCCGCGCTTCAATTTC
CGTGTTTGGGGCGAATTCTG

Downstream 100 bases:

>100_bases
GGAGATGCAGGTCCAAGACGACTCCAAGCCGTACGACGACATCAACATCACGCCGATGTTGGACCTCGCCTACGTTCTGC
TGGTGATCTTCATCATCATG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MTIEKDDVRGAGRRWSRGTKALTKVGLLAALAGMLLSATPANAWWNDDWQLRKKITIDTSAAGANITDPIGTTPVLVRLH
SGNFRFNTTKEDGSDLRFVAGDDKTPLKYHVEKFDALLGEALVWVSVPDLQPGAKTDLWLYYGNKKAAATADSKGTYDAD
TQLVYHFSERGTVPLDSTVWANNAQSVGQPAEGAIIGTGLRLDGRAPLTLPSSSALALAGSGGWTWSAWVKPASSQPNTA
LYSRRDGGNAVVIGLDNGAPFVEVANAGAVQRTATAAPVAPNSWHHVAVVAGNGRVTLYLDGNAYAVLDAALPALNTLAF
VGGDALASSAPPTATPAQTSVPLADESTPPSAATGDAPAADAAVAAAPAAMAGFTGDIDELEISKVSRPAGFVRVAAIGQ
GLDKGKLLAFSVDEESGSWLSGYFAVILKSVTLDGWVVIAILMVMAVISWMVMVDRASYLRRQARANARFMACYNAVDFD
LRLLGYGSPEDVATLGGRLDNKDAALMRSSSLYRIYHIAADEIRRRSGQGGVPTLSSNSVAAMRAALDGGVVRESQRLNR
LMVMLTIAISGGPFLGLLGTVVGVMITFAAIAASGDVNVNAIAPGIAAALVATVAGLGVAIPALFGYNYLISQIKNLTAD
VQVFVDDVVTRIAELYTSDLPAPLRRDQAAE

Sequences:

>Translated_671_residues
MTIEKDDVRGAGRRWSRGTKALTKVGLLAALAGMLLSATPANAWWNDDWQLRKKITIDTSAAGANITDPIGTTPVLVRLH
SGNFRFNTTKEDGSDLRFVAGDDKTPLKYHVEKFDALLGEALVWVSVPDLQPGAKTDLWLYYGNKKAAATADSKGTYDAD
TQLVYHFSERGTVPLDSTVWANNAQSVGQPAEGAIIGTGLRLDGRAPLTLPSSSALALAGSGGWTWSAWVKPASSQPNTA
LYSRRDGGNAVVIGLDNGAPFVEVANAGAVQRTATAAPVAPNSWHHVAVVAGNGRVTLYLDGNAYAVLDAALPALNTLAF
VGGDALASSAPPTATPAQTSVPLADESTPPSAATGDAPAADAAVAAAPAAMAGFTGDIDELEISKVSRPAGFVRVAAIGQ
GLDKGKLLAFSVDEESGSWLSGYFAVILKSVTLDGWVVIAILMVMAVISWMVMVDRASYLRRQARANARFMACYNAVDFD
LRLLGYGSPEDVATLGGRLDNKDAALMRSSSLYRIYHIAADEIRRRSGQGGVPTLSSNSVAAMRAALDGGVVRESQRLNR
LMVMLTIAISGGPFLGLLGTVVGVMITFAAIAASGDVNVNAIAPGIAAALVATVAGLGVAIPALFGYNYLISQIKNLTAD
VQVFVDDVVTRIAELYTSDLPAPLRRDQAAE
>Mature_670_residues
TIEKDDVRGAGRRWSRGTKALTKVGLLAALAGMLLSATPANAWWNDDWQLRKKITIDTSAAGANITDPIGTTPVLVRLHS
GNFRFNTTKEDGSDLRFVAGDDKTPLKYHVEKFDALLGEALVWVSVPDLQPGAKTDLWLYYGNKKAAATADSKGTYDADT
QLVYHFSERGTVPLDSTVWANNAQSVGQPAEGAIIGTGLRLDGRAPLTLPSSSALALAGSGGWTWSAWVKPASSQPNTAL
YSRRDGGNAVVIGLDNGAPFVEVANAGAVQRTATAAPVAPNSWHHVAVVAGNGRVTLYLDGNAYAVLDAALPALNTLAFV
GGDALASSAPPTATPAQTSVPLADESTPPSAATGDAPAADAAVAAAPAAMAGFTGDIDELEISKVSRPAGFVRVAAIGQG
LDKGKLLAFSVDEESGSWLSGYFAVILKSVTLDGWVVIAILMVMAVISWMVMVDRASYLRRQARANARFMACYNAVDFDL
RLLGYGSPEDVATLGGRLDNKDAALMRSSSLYRIYHIAADEIRRRSGQGGVPTLSSNSVAAMRAALDGGVVRESQRLNRL
MVMLTIAISGGPFLGLLGTVVGVMITFAAIAASGDVNVNAIAPGIAAALVATVAGLGVAIPALFGYNYLISQIKNLTADV
QVFVDDVVTRIAELYTSDLPAPLRRDQAAE

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG5306

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=106, Percent_Identity=36.7924528301887, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789381, Length=88, Percent_Identity=43.1818181818182, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 70139; Mature: 70008

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEKDDVRGAGRRWSRGTKALTKVGLLAALAGMLLSATPANAWWNDDWQLRKKITIDTS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECC
AAGANITDPIGTTPVLVRLHSGNFRFNTTKEDGSDLRFVAGDDKTPLKYHVEKFDALLGE
CCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCC
ALVWVSVPDLQPGAKTDLWLYYGNKKAAATADSKGTYDADTQLVYHFSERGTVPLDSTVW
EEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEE
ANNAQSVGQPAEGAIIGTGLRLDGRAPLTLPSSSALALAGSGGWTWSAWVKPASSQPNTA
CCCCHHCCCCCCCCEEECCEEECCCCCEECCCCCCEEEECCCCCEEEEEECCCCCCCCCE
LYSRRDGGNAVVIGLDNGAPFVEVANAGAVQRTATAAPVAPNSWHHVAVVAGNGRVTLYL
EEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEE
DGNAYAVLDAALPALNTLAFVGGDALASSAPPTATPAQTSVPLADESTPPSAATGDAPAA
CCCEEEEEHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAAVAAAPAAMAGFTGDIDELEISKVSRPAGFVRVAAIGQGLDKGKLLAFSVDEESGSWL
CHHHHHCCHHHHCCCCCCCHHHHHHCCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCHH
SGYFAVILKSVTLDGWVVIAILMVMAVISWMVMVDRASYLRRQARANARFMACYNAVDFD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEE
LRLLGYGSPEDVATLGGRLDNKDAALMRSSSLYRIYHIAADEIRRRSGQGGVPTLSSNSV
EEEEECCCCHHHHHHCCCCCCCCHHHHCCCCEEEEEEECHHHHHHHCCCCCCCCCCCCCH
AAMRAALDGGVVRESQRLNRLMVMLTIAISGGPFLGLLGTVVGVMITFAAIAASGDVNVN
HHHHHHHCCCHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
AIAPGIAAALVATVAGLGVAIPALFGYNYLISQIKNLTADVQVFVDDVVTRIAELYTSDL
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
PAPLRRDQAAE
CCCCCCCCCCC
>Mature Secondary Structure 
TIEKDDVRGAGRRWSRGTKALTKVGLLAALAGMLLSATPANAWWNDDWQLRKKITIDTS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECC
AAGANITDPIGTTPVLVRLHSGNFRFNTTKEDGSDLRFVAGDDKTPLKYHVEKFDALLGE
CCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCC
ALVWVSVPDLQPGAKTDLWLYYGNKKAAATADSKGTYDADTQLVYHFSERGTVPLDSTVW
EEEEEECCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCEE
ANNAQSVGQPAEGAIIGTGLRLDGRAPLTLPSSSALALAGSGGWTWSAWVKPASSQPNTA
CCCCHHCCCCCCCCEEECCEEECCCCCEECCCCCCEEEECCCCCEEEEEECCCCCCCCCE
LYSRRDGGNAVVIGLDNGAPFVEVANAGAVQRTATAAPVAPNSWHHVAVVAGNGRVTLYL
EEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEE
DGNAYAVLDAALPALNTLAFVGGDALASSAPPTATPAQTSVPLADESTPPSAATGDAPAA
CCCEEEEEHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAAVAAAPAAMAGFTGDIDELEISKVSRPAGFVRVAAIGQGLDKGKLLAFSVDEESGSWL
CHHHHHCCHHHHCCCCCCCHHHHHHCCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCHH
SGYFAVILKSVTLDGWVVIAILMVMAVISWMVMVDRASYLRRQARANARFMACYNAVDFD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEE
LRLLGYGSPEDVATLGGRLDNKDAALMRSSSLYRIYHIAADEIRRRSGQGGVPTLSSNSV
EEEEECCCCHHHHHHCCCCCCCCHHHHCCCCEEEEEEECHHHHHHHCCCCCCCCCCCCCH
AAMRAALDGGVVRESQRLNRLMVMLTIAISGGPFLGLLGTVVGVMITFAAIAASGDVNVN
HHHHHHHCCCHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
AIAPGIAAALVATVAGLGVAIPALFGYNYLISQIKNLTADVQVFVDDVVTRIAELYTSDL
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
PAPLRRDQAAE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]