Click here to switch to the map view.

The map label for this gene is fecR [H]

Identifier: 86749338

GI number: 86749338

Start: 2530763

End: 2531731

Strand: Direct

Name: fecR [H]

Synonym: RPB_2218

Alternate gene names: 86749338

Gene position: 2530763-2531731 (Clockwise)

Preceding gene: 86749337

Following gene: 86749339

Centisome position: 47.47

GC content: 65.94

Gene sequence:

>969_bases
ATGCCCGAGCTCGATGCCGTGCAGCGTCAGGCGCTCGCCTGGGTAATCCGGCTGAATTCCGGCGGCGCGACGTCGGACGA
CGCTGCGGCATTGGCGCTGTGGCGCAAGCGCGGGCCGGAATACGAGGATGCATTTCGAGAGGCAGTCCAATTTTGGCGAA
CTTTCGGCGAGGCGACCCGCGAATTGGTCGGCCGGAACGAGGCGCGCGCGATGCCTCCGGTTCGGTCGCGGCCGGTCCTC
AGCCGCCGGCTGCTGATCGGTGGTGGCGTCGCCGCAGCCGCTTCACTCGGCGGCATCTACGTCTCGAAGCATCCGCCGCT
CGGGTTGTGGCCTTCGATCGAGGAGCTTGCGGCCGACCACCGCACCGGCAAAGGCGAGCGCCGCAAGATCGAGGTGGCCA
AGAATGCGGTCATGACTCTGAACACGCAGACCGCGGTGTCGGTGCGGTCCGCATCGGCGACACCTCGCGTCGCGCTGATT
TCGGGCGAAGCGGCGGTCGATGTCAGCCGTGATGTCGGGGCGATGGTGATCGACGCGGCGGGAGGACGGATCGAGGCGCA
GCAGGCCAGCTTCAACGTCCGATGCGTCGACCAGAGCGTCTCGGTGGCGTGTTTCACTGGCGACGTGCAGGTCGAATGGG
AGGGCCGGCGAGCGGTGCTGGCTGCGTCTCAGCAACTGACGTATTCCGAAGAGAGCGGCCTCACGGCGGTTGCGCCTGCC
GATGCCGAACAGGCCACGGCGTGGCAGCGCGGCCTGTTGCTGGTTCACGATTGGCCGGTCGACCGATTGGTCGCCGAAAT
CAACCGCTATCGGCCCGGTCGTATCGTGATCATGAACAGCAATCTTGGTCGCCGCATGATCTCCGGGACGTTCTATCTCG
ACCATCTCGACGATTTCGTCGCGCAGGTCCACGGACTGTTCGGCGCCACTGCGCGAACGCTACCGGGCGGAATTTTGCTG
CTGAGCTGA

Upstream 100 bases:

>100_bases
ATCGTCTTAAGATCAACGCGAGTTCTGCGTGCCTGCGGGCGAGCAGGTCGCGGGTGGAGATAGTCGAAGTGAGCGACCGA
TCTTGAGCACTGCCGACCAG

Downstream 100 bases:

>100_bases
CGCGGTAATCGTCTTTCCATTTCAGCGAGGTCGTCGGACCGAACTGATGCTCGGGCCTCTCACCCCGGCGGCGCCGTCGC
GCGATCGGCCCGGCAAATCA

Product: putative FecR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPELDAVQRQALAWVIRLNSGGATSDDAAALALWRKRGPEYEDAFREAVQFWRTFGEATRELVGRNEARAMPPVRSRPVL
SRRLLIGGGVAAAASLGGIYVSKHPPLGLWPSIEELAADHRTGKGERRKIEVAKNAVMTLNTQTAVSVRSASATPRVALI
SGEAAVDVSRDVGAMVIDAAGGRIEAQQASFNVRCVDQSVSVACFTGDVQVEWEGRRAVLAASQQLTYSEESGLTAVAPA
DAEQATAWQRGLLLVHDWPVDRLVAEINRYRPGRIVIMNSNLGRRMISGTFYLDHLDDFVAQVHGLFGATARTLPGGILL
LS

Sequences:

>Translated_322_residues
MPELDAVQRQALAWVIRLNSGGATSDDAAALALWRKRGPEYEDAFREAVQFWRTFGEATRELVGRNEARAMPPVRSRPVL
SRRLLIGGGVAAAASLGGIYVSKHPPLGLWPSIEELAADHRTGKGERRKIEVAKNAVMTLNTQTAVSVRSASATPRVALI
SGEAAVDVSRDVGAMVIDAAGGRIEAQQASFNVRCVDQSVSVACFTGDVQVEWEGRRAVLAASQQLTYSEESGLTAVAPA
DAEQATAWQRGLLLVHDWPVDRLVAEINRYRPGRIVIMNSNLGRRMISGTFYLDHLDDFVAQVHGLFGATARTLPGGILL
LS
>Mature_321_residues
PELDAVQRQALAWVIRLNSGGATSDDAAALALWRKRGPEYEDAFREAVQFWRTFGEATRELVGRNEARAMPPVRSRPVLS
RRLLIGGGVAAAASLGGIYVSKHPPLGLWPSIEELAADHRTGKGERRKIEVAKNAVMTLNTQTAVSVRSASATPRVALIS
GEAAVDVSRDVGAMVIDAAGGRIEAQQASFNVRCVDQSVSVACFTGDVQVEWEGRRAVLAASQQLTYSEESGLTAVAPAD
AEQATAWQRGLLLVHDWPVDRLVAEINRYRPGRIVIMNSNLGRRMISGTFYLDHLDDFVAQVHGLFGATARTLPGGILLL
S

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=217, Percent_Identity=29.9539170506912, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 34764; Mature: 34633

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELDAVQRQALAWVIRLNSGGATSDDAAALALWRKRGPEYEDAFREAVQFWRTFGEATR
CCCHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ELVGRNEARAMPPVRSRPVLSRRLLIGGGVAAAASLGGIYVSKHPPLGLWPSIEELAADH
HHHCCCCCCCCCCCCCCCHHHHEEEECCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHC
RTGKGERRKIEVAKNAVMTLNTQTAVSVRSASATPRVALISGEAAVDVSRDVGAMVIDAA
CCCCCCCEEEEEECCEEEEEECCCEEEEECCCCCCEEEEEECCCEEEECCCCCEEEEECC
GGRIEAQQASFNVRCVDQSVSVACFTGDVQVEWEGRRAVLAASQQLTYSEESGLTAVAPA
CCEEEEECCCEEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCCCCCCCCEEEECCC
DAEQATAWQRGLLLVHDWPVDRLVAEINRYRPGRIVIMNSNLGRRMISGTFYLDHLDDFV
CCHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCCHHCCEEEHHHHHHHH
AQVHGLFGATARTLPGGILLLS
HHHHHHHCCHHHHCCCCEEEEC
>Mature Secondary Structure 
PELDAVQRQALAWVIRLNSGGATSDDAAALALWRKRGPEYEDAFREAVQFWRTFGEATR
CCHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ELVGRNEARAMPPVRSRPVLSRRLLIGGGVAAAASLGGIYVSKHPPLGLWPSIEELAADH
HHHCCCCCCCCCCCCCCCHHHHEEEECCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHC
RTGKGERRKIEVAKNAVMTLNTQTAVSVRSASATPRVALISGEAAVDVSRDVGAMVIDAA
CCCCCCCEEEEEECCEEEEEECCCEEEEECCCCCCEEEEEECCCEEEECCCCCEEEEECC
GGRIEAQQASFNVRCVDQSVSVACFTGDVQVEWEGRRAVLAASQQLTYSEESGLTAVAPA
CCEEEEECCCEEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCCCCCCCCEEEECCC
DAEQATAWQRGLLLVHDWPVDRLVAEINRYRPGRIVIMNSNLGRRMISGTFYLDHLDDFV
CCHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCCHHCCEEEHHHHHHHH
AQVHGLFGATARTLPGGILLLS
HHHHHHHCCHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]