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The map label for this gene is fecR [H]

Identifier: 86749326

GI number: 86749326

Start: 2498106

End: 2499092

Strand: Direct

Name: fecR [H]

Synonym: RPB_2206

Alternate gene names: 86749326

Gene position: 2498106-2499092 (Clockwise)

Preceding gene: 86749325

Following gene: 86749327

Centisome position: 46.85

GC content: 67.88

Gene sequence:

>987_bases
ATGATCGACAACGACCAGCAAGACCGCGAACTGACGCCGATCGAGCGTGAGGCGCATGCGTGGGTCCGGCGGCTCACGTC
GGGGCATGCGAGCGCCGCCGACGGCGCTGCGCTGCGTGAATGGTGCAGCCGAAACCCGGGCAACGCCGCGGCCTTCTCGG
AGGCGAGCCAGTTCTGGACCGCGCTCGGTTCGGCGGGGCGGTCCTTGCGGGAGGATGCGGGAGCACAGAAGCGCGGTCCT
GCGTCGCGGCGCCATGGCGTCGTCACGACGCGCCGGGCGGTCCTGGCCGGGGCGCTCGCAGCATCGGCAGCCGGGGTGAT
GATCGTCCGGCCGCCATTGGAACTGTGGCCCTCGCTGTCCGAGCTCCGGGCGGACTATCGCACGGGGCCCGGCGAACAGC
GCCAAATCTCGCTTGCCGACGAAGTATCGGTGCAGATGGACAGCAAGACCAGCCTTGCCGTCGCGCCCGCTGGCGGCGCC
GCCGGTGTCGAACTGATCGCTGGCCAGGCGTCGTTCAAGTTGCCGGAGCAAGGCGTAGCGCCGTTCAGAGTGATCGCAGG
GCAAGGACGCAGCTCCGCGGTCAAGGCTCATTTTGACATCCGTCTGGCCGGAACGTCGGTCTGCGTGACCTGTCTGTCGC
ACCAGGTCGACATCGACTATCGCGGCCAGCGAGCGGTGCTGCAGGAGCGACAGCAGGTGTTCTATGGCGAACGCGGACTC
GGCGCCGTGGCGACGATCGATCCGGCGGTCGTCTCGGCGTGGCAGACCGGCCTGCTCATCTTCAACATGACGCCGCTCCG
TGAGGTGATCGACGAACTCAACCGATATCGGTCCGGACGCATCATCCTGCTGGCGTCCCGGATGGCGGGAAGTCCGGTCA
AGGGCCGGTTCAGGATCGATCGTCCCGACGAGGCGCTGGCGCAGATCCAGCGTGCGTTTGACGTCGAGCGCCGCGATCTG
CCGGGCGGCATTGTACTGCTGAGCTAG

Upstream 100 bases:

>100_bases
TATGCGGGAGCGGCCTACGAGACGTGTCTGCTACATGATTGCCGCATGTCGCGACGGCGGAGCGTCGCTTCGGCAGCGGG
AAACGGATTTCCACTGATTC

Downstream 100 bases:

>100_bases
CCACCGGAGATCGCACGGCCTCACCGGCGCAGCGGCCGAGAAGTTGTGCGCATGCCGATGCGCTACAGGCTGACACGTAA
CCTTCACAAAAATCCTTTGA

Product: putative FecR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MIDNDQQDRELTPIEREAHAWVRRLTSGHASAADGAALREWCSRNPGNAAAFSEASQFWTALGSAGRSLREDAGAQKRGP
ASRRHGVVTTRRAVLAGALAASAAGVMIVRPPLELWPSLSELRADYRTGPGEQRQISLADEVSVQMDSKTSLAVAPAGGA
AGVELIAGQASFKLPEQGVAPFRVIAGQGRSSAVKAHFDIRLAGTSVCVTCLSHQVDIDYRGQRAVLQERQQVFYGERGL
GAVATIDPAVVSAWQTGLLIFNMTPLREVIDELNRYRSGRIILLASRMAGSPVKGRFRIDRPDEALAQIQRAFDVERRDL
PGGIVLLS

Sequences:

>Translated_328_residues
MIDNDQQDRELTPIEREAHAWVRRLTSGHASAADGAALREWCSRNPGNAAAFSEASQFWTALGSAGRSLREDAGAQKRGP
ASRRHGVVTTRRAVLAGALAASAAGVMIVRPPLELWPSLSELRADYRTGPGEQRQISLADEVSVQMDSKTSLAVAPAGGA
AGVELIAGQASFKLPEQGVAPFRVIAGQGRSSAVKAHFDIRLAGTSVCVTCLSHQVDIDYRGQRAVLQERQQVFYGERGL
GAVATIDPAVVSAWQTGLLIFNMTPLREVIDELNRYRSGRIILLASRMAGSPVKGRFRIDRPDEALAQIQRAFDVERRDL
PGGIVLLS
>Mature_328_residues
MIDNDQQDRELTPIEREAHAWVRRLTSGHASAADGAALREWCSRNPGNAAAFSEASQFWTALGSAGRSLREDAGAQKRGP
ASRRHGVVTTRRAVLAGALAASAAGVMIVRPPLELWPSLSELRADYRTGPGEQRQISLADEVSVQMDSKTSLAVAPAGGA
AGVELIAGQASFKLPEQGVAPFRVIAGQGRSSAVKAHFDIRLAGTSVCVTCLSHQVDIDYRGQRAVLQERQQVFYGERGL
GAVATIDPAVVSAWQTGLLIFNMTPLREVIDELNRYRSGRIILLASRMAGSPVKGRFRIDRPDEALAQIQRAFDVERRDL
PGGIVLLS

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=308, Percent_Identity=25.6493506493506, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 35312; Mature: 35312

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDNDQQDRELTPIEREAHAWVRRLTSGHASAADGAALREWCSRNPGNAAAFSEASQFWT
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
ALGSAGRSLREDAGAQKRGPASRRHGVVTTRRAVLAGALAASAAGVMIVRPPLELWPSLS
HHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHCCCHH
ELRADYRTGPGEQRQISLADEVSVQMDSKTSLAVAPAGGAAGVELIAGQASFKLPEQGVA
HHHHHHCCCCCCCCEEEEHHHCEEEECCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCC
PFRVIAGQGRSSAVKAHFDIRLAGTSVCVTCLSHQVDIDYRGQRAVLQERQQVFYGERGL
CEEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
GAVATIDPAVVSAWQTGLLIFNMTPLREVIDELNRYRSGRIILLASRMAGSPVKGRFRID
CEEEECCHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEC
RPDEALAQIQRAFDVERRDLPGGIVLLS
CCHHHHHHHHHHHCCHHHCCCCCEEEEC
>Mature Secondary Structure
MIDNDQQDRELTPIEREAHAWVRRLTSGHASAADGAALREWCSRNPGNAAAFSEASQFWT
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHH
ALGSAGRSLREDAGAQKRGPASRRHGVVTTRRAVLAGALAASAAGVMIVRPPLELWPSLS
HHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCEEEECCCHHHCCCHH
ELRADYRTGPGEQRQISLADEVSVQMDSKTSLAVAPAGGAAGVELIAGQASFKLPEQGVA
HHHHHHCCCCCCCCEEEEHHHCEEEECCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCC
PFRVIAGQGRSSAVKAHFDIRLAGTSVCVTCLSHQVDIDYRGQRAVLQERQQVFYGERGL
CEEEEECCCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
GAVATIDPAVVSAWQTGLLIFNMTPLREVIDELNRYRSGRIILLASRMAGSPVKGRFRID
CEEEECCHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEC
RPDEALAQIQRAFDVERRDLPGGIVLLS
CCHHHHHHHHHHHCCHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]