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The map label for this gene is fecI [H]

Identifier: 86749325

GI number: 86749325

Start: 2497408

End: 2497989

Strand: Direct

Name: fecI [H]

Synonym: RPB_2205

Alternate gene names: 86749325

Gene position: 2497408-2497989 (Clockwise)

Preceding gene: 86749324

Following gene: 86749326

Centisome position: 46.84

GC content: 61.34

Gene sequence:

>582_bases
ATGAGTAGAGCTCCGTGCAATTCGGATGGGACCGCGCATGGTCTCGGAGAGGCAGTTCCTGTCTTGCGTGAATCTTTCGG
CCAACGGAGTCTGTTGACGGTCATGGTCGATCGCTACGGCGATCTGCGACGCCGTCTGACACGTCGATTGGGATCTGCCG
ACTGGGCCGACGATGCGTTGCAAGATACTTATGTGCGCCTGAACGGCAGCGAAGTCGTCGGCGAGGTGCGCAACCCCGTT
GCATATTTGTTGCGCGCGGCCTTCAACAACGCGTTGAATCTGCGGCGGGCGGAAACCAGACGCCTGAGCGCCGATGAAGT
CGACGCGTTGCTGCACATTGCCGACGACGCCCCCGACGTCTTGCGGATCATCGAGGGGCGCTCCGACATCGAGAGGCTGA
AGCGGATCATGACGGAGTTGACGCCGCGCCAGCGGGAGATCCTGCTCGCAGCCCGCGTCGACGGCCTGTCGCGGCATGAG
ATCGCCGACCGGTTGGGGATCTCGGTGAGTCTGGTCGAGAAAGAACTGCGACGCGCTCAAGAATTTTGCATGTTACGCTT
CCAGCAGAAAACGCCGCGGTAG

Upstream 100 bases:

>100_bases
CCTCCACCGCGGATGGCGCAACCGTTCACGATGATCGTCCTGCCGCAGACGACCTCGACGGCTGGCTTCTGTCCACCGAG
GCTTGCGCGCGGATCGCGCG

Downstream 100 bases:

>100_bases
CGAATTGTGATGAGAATATGCGGGAGCGGCCTACGAGACGTGTCTGCTACATGATTGCCGCATGTCGCGACGGCGGAGCG
TCGCTTCGGCAGCGGGAAAC

Product: sigma-24 (FecI-like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSRAPCNSDGTAHGLGEAVPVLRESFGQRSLLTVMVDRYGDLRRRLTRRLGSADWADDALQDTYVRLNGSEVVGEVRNPV
AYLLRAAFNNALNLRRAETRRLSADEVDALLHIADDAPDVLRIIEGRSDIERLKRIMTELTPRQREILLAARVDGLSRHE
IADRLGISVSLVEKELRRAQEFCMLRFQQKTPR

Sequences:

>Translated_193_residues
MSRAPCNSDGTAHGLGEAVPVLRESFGQRSLLTVMVDRYGDLRRRLTRRLGSADWADDALQDTYVRLNGSEVVGEVRNPV
AYLLRAAFNNALNLRRAETRRLSADEVDALLHIADDAPDVLRIIEGRSDIERLKRIMTELTPRQREILLAARVDGLSRHE
IADRLGISVSLVEKELRRAQEFCMLRFQQKTPR
>Mature_192_residues
SRAPCNSDGTAHGLGEAVPVLRESFGQRSLLTVMVDRYGDLRRRLTRRLGSADWADDALQDTYVRLNGSEVVGEVRNPVA
YLLRAAFNNALNLRRAETRRLSADEVDALLHIADDAPDVLRIIEGRSDIERLKRIMTELTPRQREILLAARVDGLSRHEI
ADRLGISVSLVEKELRRAQEFCMLRFQQKTPR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates the fec genes for iron dicitrate transport (Probable) [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790746, Length=152, Percent_Identity=33.5526315789474, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21889; Mature: 21758

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAPCNSDGTAHGLGEAVPVLRESFGQRSLLTVMVDRYGDLRRRLTRRLGSADWADDAL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QDTYVRLNGSEVVGEVRNPVAYLLRAAFNNALNLRRAETRRLSADEVDALLHIADDAPDV
HHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
LRIIEGRSDIERLKRIMTELTPRQREILLAARVDGLSRHEIADRLGISVSLVEKELRRAQ
HHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHH
EFCMLRFQQKTPR
HHHHHHHHHCCCC
>Mature Secondary Structure 
SRAPCNSDGTAHGLGEAVPVLRESFGQRSLLTVMVDRYGDLRRRLTRRLGSADWADDAL
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QDTYVRLNGSEVVGEVRNPVAYLLRAAFNNALNLRRAETRRLSADEVDALLHIADDAPDV
HHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHH
LRIIEGRSDIERLKRIMTELTPRQREILLAARVDGLSRHEIADRLGISVSLVEKELRRAQ
HHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHH
EFCMLRFQQKTPR
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503; 8052622 [H]