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The map label for this gene is crt [H]

Identifier: 86749242

GI number: 86749242

Start: 2411942

End: 2413015

Strand: Direct

Name: crt [H]

Synonym: RPB_2121

Alternate gene names: 86749242

Gene position: 2411942-2413015 (Clockwise)

Preceding gene: 86749241

Following gene: 86749243

Centisome position: 45.24

GC content: 66.48

Gene sequence:

>1074_bases
ATGAATATAGCGGTCACTGAGCCGGACCTGATCGTCCGGCGCGAGGGCGCAGCCGGCGTGGTCCGCCTCAACCGGCCGAA
AGCGCTGAATGCGCTGACGCTGGAGATGGCGCGCGGCCTCGACGCCGCGTTGACCGAGTTCGAGGCCGATCCGGCCATCG
CGTTGATCCTGATCGAAGGCGCCGGTGAGCGCGGCCTGTGCGCCGGCGGCGACATCGTCGGGCTGTACAACAGCGCGCGC
GAAGGCGGCGATCTCGGCAAAGTGTTCTGGCGCGAAGAATACGTCATGAACGCGCGGATCGCGAAATTTCCCAAGCCCTA
TGTCGCCTATATGGATGGCTTCGTGATGGGCGGCGGCGTCGGCATCGCTGGTCACGGCAGCCATCGCATCGTCACCGACA
AGACCAAGATCGCAATGCCGGAAGTCGGCATCGGCTTCTTCCCCGATGTCGGCGGCACCTGGCTGCTGTCGCGCGCGCCC
GGCGAGATCGGCACCTATTTCGGCCTCACCGGCGAGACCATGAACGGCGCCGACGCGATCCACACGAGGTTTGCGGATGC
GTTCGTGCCGGCATCCGCATGGCCTGAACTCCGCGCCGCGCTGACGACGGCGTCGGCCGACGCCCACGCCGACAATGTCC
GCGGCATTCTCGCGCGATTCACGATGACACCCGAAGCCGGGCCGGCGCAGCGTCACGCGCAGCAGATCGACCAATGGTTC
GCCCACGATACCGTCGAGGCGATCTTCGCGGATCTCGAGCGCGACCGCTCGGACTTCGCGCAGGCGACGCTGAAAGCGCT
GCGGGCCAAGTCGCCGACCAGCCTCAAGGTCGCGCTGAAGCTGTTGCGGATCGCGCGTGACGCGGCGTCGCTCGAAGACT
GCCTGGTGCACGAATATCGCGCCGCGCTGCAGGTGTTCGTGAGCTATGATTTCGTCGAGGGCATTCGCGCCGCGGTGATC
GACAAGGACCGCGCGCCGAAATGGCGGCCGGCGACGATCGAGGAGGTGACGCCGGACATCGTGGCGCGCTACTTTGACGA
TCGCGGCGACGACGAGCTGAAATTGCCGGACTGA

Upstream 100 bases:

>100_bases
TCGAGAAGATCGTGCGCGATCTGCGCGTGCACCAGATCCTCGAAGGCACCAACGAGATCATGCGGCTGATCGTGTCGCGC
AAGCTGCTCGAGGAGAACCG

Downstream 100 bases:

>100_bases
AGAGCCGGGCCCGCCGACAACAAGAAGGGGAGGACTATGACGACAATCGCATTCATCGGTCTCGGCAATATGGGCGGGCC
GATGGCCGCCAATCTGGTCA

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNIAVTEPDLIVRREGAAGVVRLNRPKALNALTLEMARGLDAALTEFEADPAIALILIEGAGERGLCAGGDIVGLYNSAR
EGGDLGKVFWREEYVMNARIAKFPKPYVAYMDGFVMGGGVGIAGHGSHRIVTDKTKIAMPEVGIGFFPDVGGTWLLSRAP
GEIGTYFGLTGETMNGADAIHTRFADAFVPASAWPELRAALTTASADAHADNVRGILARFTMTPEAGPAQRHAQQIDQWF
AHDTVEAIFADLERDRSDFAQATLKALRAKSPTSLKVALKLLRIARDAASLEDCLVHEYRAALQVFVSYDFVEGIRAAVI
DKDRAPKWRPATIEEVTPDIVARYFDDRGDDELKLPD

Sequences:

>Translated_357_residues
MNIAVTEPDLIVRREGAAGVVRLNRPKALNALTLEMARGLDAALTEFEADPAIALILIEGAGERGLCAGGDIVGLYNSAR
EGGDLGKVFWREEYVMNARIAKFPKPYVAYMDGFVMGGGVGIAGHGSHRIVTDKTKIAMPEVGIGFFPDVGGTWLLSRAP
GEIGTYFGLTGETMNGADAIHTRFADAFVPASAWPELRAALTTASADAHADNVRGILARFTMTPEAGPAQRHAQQIDQWF
AHDTVEAIFADLERDRSDFAQATLKALRAKSPTSLKVALKLLRIARDAASLEDCLVHEYRAALQVFVSYDFVEGIRAAVI
DKDRAPKWRPATIEEVTPDIVARYFDDRGDDELKLPD
>Mature_357_residues
MNIAVTEPDLIVRREGAAGVVRLNRPKALNALTLEMARGLDAALTEFEADPAIALILIEGAGERGLCAGGDIVGLYNSAR
EGGDLGKVFWREEYVMNARIAKFPKPYVAYMDGFVMGGGVGIAGHGSHRIVTDKTKIAMPEVGIGFFPDVGGTWLLSRAP
GEIGTYFGLTGETMNGADAIHTRFADAFVPASAWPELRAALTTASADAHADNVRGILARFTMTPEAGPAQRHAQQIDQWF
AHDTVEAIFADLERDRSDFAQATLKALRAKSPTSLKVALKLLRIARDAASLEDCLVHEYRAALQVFVSYDFVEGIRAAVI
DKDRAPKWRPATIEEVTPDIVARYFDDRGDDELKLPD

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=352, Percent_Identity=37.7840909090909, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI37594469, Length=299, Percent_Identity=37.123745819398, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=27.6679841897233, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1787659, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787660, Length=148, Percent_Identity=35.8108108108108, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI221142681, Length=173, Percent_Identity=28.9017341040462, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=349, Percent_Identity=39.2550143266476, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI25144160, Length=349, Percent_Identity=39.2550143266476, Blast_Score=243, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17554946, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=355, Percent_Identity=32.3943661971831, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI28571730, Length=357, Percent_Identity=39.2156862745098, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI28571729, Length=357, Percent_Identity=39.2156862745098, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI20129971, Length=178, Percent_Identity=34.8314606741573, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24653477, Length=178, Percent_Identity=34.8314606741573, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 38725; Mature: 38725

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAVTEPDLIVRREGAAGVVRLNRPKALNALTLEMARGLDAALTEFEADPAIALILIEG
CCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEEC
AGERGLCAGGDIVGLYNSAREGGDLGKVFWREEYVMNARIAKFPKPYVAYMDGFVMGGGV
CCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEECCCE
GIAGHGSHRIVTDKTKIAMPEVGIGFFPDVGGTWLLSRAPGEIGTYFGLTGETMNGADAI
EECCCCCCEEEECCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCEECCCCCCCCCHHHH
HTRFADAFVPASAWPELRAALTTASADAHADNVRGILARFTMTPEAGPAQRHAQQIDQWF
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
AHDTVEAIFADLERDRSDFAQATLKALRAKSPTSLKVALKLLRIARDAASLEDCLVHEYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALQVFVSYDFVEGIRAAVIDKDRAPKWRPATIEEVTPDIVARYFDDRGDDELKLPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNIAVTEPDLIVRREGAAGVVRLNRPKALNALTLEMARGLDAALTEFEADPAIALILIEG
CCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEEC
AGERGLCAGGDIVGLYNSAREGGDLGKVFWREEYVMNARIAKFPKPYVAYMDGFVMGGGV
CCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEECCCE
GIAGHGSHRIVTDKTKIAMPEVGIGFFPDVGGTWLLSRAPGEIGTYFGLTGETMNGADAI
EECCCCCCEEEECCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCEECCCCCCCCCHHHH
HTRFADAFVPASAWPELRAALTTASADAHADNVRGILARFTMTPEAGPAQRHAQQIDQWF
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
AHDTVEAIFADLERDRSDFAQATLKALRAKSPTSLKVALKLLRIARDAASLEDCLVHEYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALQVFVSYDFVEGIRAAVIDKDRAPKWRPATIEEVTPDIVARYFDDRGDDELKLPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]