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The map label for this gene is 86749226

Identifier: 86749226

GI number: 86749226

Start: 2394181

End: 2395395

Strand: Direct

Name: 86749226

Synonym: RPB_2105

Alternate gene names: NA

Gene position: 2394181-2395395 (Clockwise)

Preceding gene: 86749225

Following gene: 86749227

Centisome position: 44.91

GC content: 67.65

Gene sequence:

>1215_bases
ATGGATTCCGGGTTCGCGCCAAGGGGCGCGCCCCGGAATGACGAAAGTGAGGATGATGCCAAGCGTCGGACGTTCATCAT
GAGCTACATCACCGGCGTCGGCCTCACGCCGTTCGGCAAGATCGATGGTTCGACGACGCTGTCGCTGATGCGCGACGCTG
CCGAGCAGGCGCTCGCCGATGCGGAACTGACCCGCTCCGACATCGACGGGCTGCTGTGCGGCTATTCGACGACGATGCCG
CACATCATGCTGGCCACCGTGTTCGCCGAGCATTTCGGCATTCGTCCCGCCTACTGCCACGCCGTGCAGGTCGGCGGCGC
CACCGGGATGGCGATGGCGATGCTGGCGCATCAGCTGGTCGAGAGCGGTGCGGCGAAGAACATTCTGGTGGTCGGCGGCG
AAAATCGCCTGAGCGGGCAGAGCCGCGACGCCTCCGTGCAGGCGCTGGCGCAGGTCGGCCACCCGGTCTACGAAGTGCCG
CTCGGCCCGACCATCCCCGCGTATTATGGCCTGGTCGCGTCGCGCTACATGCACCAGCACGGCGTCAGCGAGGAAGACCT
CGCCGCATTCGCCGTGCTGATGCGCGCGCACGCGGCCCTCCATCCCGGTGCGCAGTTTCACGAGCCGATCAGCATCGCCG
AGGTGATGGCGTCGAAGCCGATCGCCACGCCGCTGAAACTGCTCGATTGCTGTCCTGTGTCCGATGGCGGCGCGGCGCTG
ATCGTCAGCCGCGAGCCGACCACGACTCATCGTATCAAGGTCCGCGGTTGCGGCCAGGCGCATACCCATCAGCACGTCAC
CGCGATGCCGGCGGACGGCCCGTCCGGCGCGGAGCAGTCGATCGCGCGTGCCAAAGCTGCGAGCGGCGTGGCACTCGGCG
ATATTCGCTACGCCGCGGTGTATGACAGCTTCACCATCACGCTGCTGATGCTGCTGGAAGATCTCGGCCTCGCGCCCCGC
GGCGAGGCGGCGGCGCGCGCCCGCGATGGTTACTTCTCGCGCGACGGCGCGATGCCGCTCAACACCCATGGCGGGCTGTT
GTCCTACGGCCATTGCGGCGTCGGTGGCGCGATGGCGCATCTGGTCGAGACCCATCTGCAGATGACCGGTCGGGCCGATG
ATCGCCAGGTCCGCGACGCCTCGCTGGCGTTGCTGCATGGCGACGGCGGCGTGCTGTCGTCGCATGTCAGCATGTTCCTG
GAGCGGGTGCGATGA

Upstream 100 bases:

>100_bases
AATCGATGCGCGTGATCGCTGACCATCGCAGACACCCTCTCGTTCGTCATTCCGGGGCGCGCGTAGCGCGAACCCGGAAT
CCATACTCCCGGCGGTGGCT

Downstream 100 bases:

>100_bases
GTGAGCCGGCGATGATCTCCGACTGGACCGCCGGCGACGAGGCCATCAGCGATCAGCGCTGCACCGCCTGCGGCGGCGTG
CAGTATTTCCGCCGCGACTT

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDSGFAPRGAPRNDESEDDAKRRTFIMSYITGVGLTPFGKIDGSTTLSLMRDAAEQALADAELTRSDIDGLLCGYSTTMP
HIMLATVFAEHFGIRPAYCHAVQVGGATGMAMAMLAHQLVESGAAKNILVVGGENRLSGQSRDASVQALAQVGHPVYEVP
LGPTIPAYYGLVASRYMHQHGVSEEDLAAFAVLMRAHAALHPGAQFHEPISIAEVMASKPIATPLKLLDCCPVSDGGAAL
IVSREPTTTHRIKVRGCGQAHTHQHVTAMPADGPSGAEQSIARAKAASGVALGDIRYAAVYDSFTITLLMLLEDLGLAPR
GEAAARARDGYFSRDGAMPLNTHGGLLSYGHCGVGGAMAHLVETHLQMTGRADDRQVRDASLALLHGDGGVLSSHVSMFL
ERVR

Sequences:

>Translated_404_residues
MDSGFAPRGAPRNDESEDDAKRRTFIMSYITGVGLTPFGKIDGSTTLSLMRDAAEQALADAELTRSDIDGLLCGYSTTMP
HIMLATVFAEHFGIRPAYCHAVQVGGATGMAMAMLAHQLVESGAAKNILVVGGENRLSGQSRDASVQALAQVGHPVYEVP
LGPTIPAYYGLVASRYMHQHGVSEEDLAAFAVLMRAHAALHPGAQFHEPISIAEVMASKPIATPLKLLDCCPVSDGGAAL
IVSREPTTTHRIKVRGCGQAHTHQHVTAMPADGPSGAEQSIARAKAASGVALGDIRYAAVYDSFTITLLMLLEDLGLAPR
GEAAARARDGYFSRDGAMPLNTHGGLLSYGHCGVGGAMAHLVETHLQMTGRADDRQVRDASLALLHGDGGVLSSHVSMFL
ERVR
>Mature_404_residues
MDSGFAPRGAPRNDESEDDAKRRTFIMSYITGVGLTPFGKIDGSTTLSLMRDAAEQALADAELTRSDIDGLLCGYSTTMP
HIMLATVFAEHFGIRPAYCHAVQVGGATGMAMAMLAHQLVESGAAKNILVVGGENRLSGQSRDASVQALAQVGHPVYEVP
LGPTIPAYYGLVASRYMHQHGVSEEDLAAFAVLMRAHAALHPGAQFHEPISIAEVMASKPIATPLKLLDCCPVSDGGAAL
IVSREPTTTHRIKVRGCGQAHTHQHVTAMPADGPSGAEQSIARAKAASGVALGDIRYAAVYDSFTITLLMLLEDLGLAPR
GEAAARARDGYFSRDGAMPLNTHGGLLSYGHCGVGGAMAHLVETHLQMTGRADDRQVRDASLALLHGDGGVLSSHVSMFL
ERVR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=406, Percent_Identity=27.3399014778325, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI302344767, Length=308, Percent_Identity=27.9220779220779, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI302344760, Length=303, Percent_Identity=29.7029702970297, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI302344762, Length=384, Percent_Identity=26.5625, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI55956775, Length=347, Percent_Identity=25.9365994236311, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17537653, Length=385, Percent_Identity=24.9350649350649, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585051, Length=382, Percent_Identity=26.9633507853403, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19921506, Length=381, Percent_Identity=26.246719160105, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 42598; Mature: 42598

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSGFAPRGAPRNDESEDDAKRRTFIMSYITGVGLTPFGKIDGSTTLSLMRDAAEQALAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AELTRSDIDGLLCGYSTTMPHIMLATVFAEHFGIRPAYCHAVQVGGATGMAMAMLAHQLV
HHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHH
ESGAAKNILVVGGENRLSGQSRDASVQALAQVGHPVYEVPLGPTIPAYYGLVASRYMHQH
HCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHC
GVSEEDLAAFAVLMRAHAALHPGAQFHEPISIAEVMASKPIATPLKLLDCCPVSDGGAAL
CCCHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEE
IVSREPTTTHRIKVRGCGQAHTHQHVTAMPADGPSGAEQSIARAKAASGVALGDIRYAAV
EEECCCCCEEEEEEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEECCEEEEHH
YDSFTITLLMLLEDLGLAPRGEAAARARDGYFSRDGAMPLNTHGGLLSYGHCGVGGAMAH
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHH
LVETHLQMTGRADDRQVRDASLALLHGDGGVLSSHVSMFLERVR
HHHHHHHHCCCCCCHHHCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSGFAPRGAPRNDESEDDAKRRTFIMSYITGVGLTPFGKIDGSTTLSLMRDAAEQALAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AELTRSDIDGLLCGYSTTMPHIMLATVFAEHFGIRPAYCHAVQVGGATGMAMAMLAHQLV
HHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHH
ESGAAKNILVVGGENRLSGQSRDASVQALAQVGHPVYEVPLGPTIPAYYGLVASRYMHQH
HCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHC
GVSEEDLAAFAVLMRAHAALHPGAQFHEPISIAEVMASKPIATPLKLLDCCPVSDGGAAL
CCCHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEE
IVSREPTTTHRIKVRGCGQAHTHQHVTAMPADGPSGAEQSIARAKAASGVALGDIRYAAV
EEECCCCCEEEEEEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEECCEEEEHH
YDSFTITLLMLLEDLGLAPRGEAAARARDGYFSRDGAMPLNTHGGLLSYGHCGVGGAMAH
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHH
LVETHLQMTGRADDRQVRDASLALLHGDGGVLSSHVSMFLERVR
HHHHHHHHCCCCCCHHHCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]