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The map label for this gene is yqeF [C]

Identifier: 86749222

GI number: 86749222

Start: 2388707

End: 2389876

Strand: Direct

Name: yqeF [C]

Synonym: RPB_2101

Alternate gene names: 86749222

Gene position: 2388707-2389876 (Clockwise)

Preceding gene: 86749221

Following gene: 86749223

Centisome position: 44.8

GC content: 66.84

Gene sequence:

>1170_bases
ATGACCGCCAGCATCGTTGGATGGGCGCATATGCCCTTCGGCAAGTTCGACGCCGAGACCGTCGAGAGCATGATCGTCCG
CGTCGCCAATGAGGCGATCGCCGATGCCGGCATCGCCGCCGGCGATGTCGATGAAATCGTGCTGGGGCATTTCAACGCCG
GCTTCTCGCCGCAGGATTTCACCGCCGCTCTGGTGCTGCAGGCCGATCCGGCGCTGCGCTTCAAGCCCGCCACCCGGGTC
GAGAACGCCTGCGCCACCGGCTCCGCCGCCGTGCATCAGGGCATCCGCGCGATCGAGGCCGGCGCCGCCAAGGTGGTGCT
GGTGGTCGGCGTCGAGCAGATGACGCGGACGCCGGGCCCGGAAATCGGCAAGAACCTGCTGCGCGCCTCCTATCTGCCGG
AAGACGGCGAGACGCCCGCGGGCTTCGCCGGGGTGTTCGGCATCATCGCGCAACGATACTTCCAGAAATACGGCGACCAG
TCCGACGCCCTCGCCATGATCGCCGCCAAGAACCACCACAACGGAGTGGCCAATCCCTATGCGCAGATGCGCAAGGATTT
CGGTTTCGAGTTCTGCCGCGCCGAGGGCGAGAAGAACCCGTTCGTCGCCGGCCCCCTGAAGCGCACCGACTGCTCGCTCG
TCTCCGACGGCGCCGCCGCGCTGGTGCTGACTTCGGCGGAGAACGCCAAGACCATGGGCAAGGCCGTCAACATCCGCGCC
CGCGCCCATGCGCAGGATTTCCTGCCGATGTCCAAGCGCGACATCCTGCAGTTCGAAGGCTGCACCGTCGCCTGGCAGCG
CGCGCTGGCCGACGCCGGAATCACGCTCGATGATCTCTCCTTCGTCGAGACCCACGATTGCTTCACCATCGCCGAACTGA
TCGAGTACGAAGCGATGGGGCTGACCACGAAGGGGCAGGGCGCCCGCGCCATCAAGGAAGGCTGGACCCAGAAGGACGGC
AAGCTGCCGATCAATCCGTCCGGCGGCCTCAAGGCCAAGGGCCATCCGATCGGCGCCACCGGCGTGTCGATGCACGTGCT
GACCGCGATGCAGCTGCTCGGCCAGGCGCCGGAAGGCATGCAGATCAAGGACGCCAAGCTCGGCGGCATCTTCAACATGG
GCGGCGCCGCCGTCGCCAACTACGTCTCGGTGCTCGAGCCGGCGAAGTAA

Upstream 100 bases:

>100_bases
CGGGCATGACGAGTCTTTATGCGTCCCACGGGGGGATGCTTTTGGCTGACGGTCGTCCTATATTCCGGCCAAACCAGCAA
CCCGATCGAGGAGAAACGCC

Downstream 100 bases:

>100_bases
TCCAACGCGATGGCTCTCTCGCCCGTCATGCCCGGGCTTGTCCCGGGCATCCACGCCTTCGGCGGTGGACGCGGCAAAGA
CGTGGATGGCCGGGACAAGC

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTASIVGWAHMPFGKFDAETVESMIVRVANEAIADAGIAAGDVDEIVLGHFNAGFSPQDFTAALVLQADPALRFKPATRV
ENACATGSAAVHQGIRAIEAGAAKVVLVVGVEQMTRTPGPEIGKNLLRASYLPEDGETPAGFAGVFGIIAQRYFQKYGDQ
SDALAMIAAKNHHNGVANPYAQMRKDFGFEFCRAEGEKNPFVAGPLKRTDCSLVSDGAAALVLTSAENAKTMGKAVNIRA
RAHAQDFLPMSKRDILQFEGCTVAWQRALADAGITLDDLSFVETHDCFTIAELIEYEAMGLTTKGQGARAIKEGWTQKDG
KLPINPSGGLKAKGHPIGATGVSMHVLTAMQLLGQAPEGMQIKDAKLGGIFNMGGAAVANYVSVLEPAK

Sequences:

>Translated_389_residues
MTASIVGWAHMPFGKFDAETVESMIVRVANEAIADAGIAAGDVDEIVLGHFNAGFSPQDFTAALVLQADPALRFKPATRV
ENACATGSAAVHQGIRAIEAGAAKVVLVVGVEQMTRTPGPEIGKNLLRASYLPEDGETPAGFAGVFGIIAQRYFQKYGDQ
SDALAMIAAKNHHNGVANPYAQMRKDFGFEFCRAEGEKNPFVAGPLKRTDCSLVSDGAAALVLTSAENAKTMGKAVNIRA
RAHAQDFLPMSKRDILQFEGCTVAWQRALADAGITLDDLSFVETHDCFTIAELIEYEAMGLTTKGQGARAIKEGWTQKDG
KLPINPSGGLKAKGHPIGATGVSMHVLTAMQLLGQAPEGMQIKDAKLGGIFNMGGAAVANYVSVLEPAK
>Mature_388_residues
TASIVGWAHMPFGKFDAETVESMIVRVANEAIADAGIAAGDVDEIVLGHFNAGFSPQDFTAALVLQADPALRFKPATRVE
NACATGSAAVHQGIRAIEAGAAKVVLVVGVEQMTRTPGPEIGKNLLRASYLPEDGETPAGFAGVFGIIAQRYFQKYGDQS
DALAMIAAKNHHNGVANPYAQMRKDFGFEFCRAEGEKNPFVAGPLKRTDCSLVSDGAAALVLTSAENAKTMGKAVNIRAR
AHAQDFLPMSKRDILQFEGCTVAWQRALADAGITLDDLSFVETHDCFTIAELIEYEAMGLTTKGQGARAIKEGWTQKDGK
LPINPSGGLKAKGHPIGATGVSMHVLTAMQLLGQAPEGMQIKDAKLGGIFNMGGAAVANYVSVLEPAK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=368, Percent_Identity=33.1521739130435, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI302344760, Length=323, Percent_Identity=35.2941176470588, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI302344767, Length=323, Percent_Identity=35.2941176470588, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI302344762, Length=310, Percent_Identity=34.5161290322581, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI55956775, Length=272, Percent_Identity=34.9264705882353, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17537653, Length=353, Percent_Identity=32.5779036827195, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585051, Length=366, Percent_Identity=34.6994535519126, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI19921506, Length=366, Percent_Identity=33.3333333333333, Blast_Score=161, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 41046; Mature: 40915

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASIVGWAHMPFGKFDAETVESMIVRVANEAIADAGIAAGDVDEIVLGHFNAGFSPQDF
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
TAALVLQADPALRFKPATRVENACATGSAAVHQGIRAIEAGAAKVVLVVGVEQMTRTPGP
EEEEEEECCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCH
EIGKNLLRASYLPEDGETPAGFAGVFGIIAQRYFQKYGDQSDALAMIAAKNHHNGVANPY
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHH
AQMRKDFGFEFCRAEGEKNPFVAGPLKRTDCSLVSDGAAALVLTSAENAKTMGKAVNIRA
HHHHHHHCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEEE
RAHAQDFLPMSKRDILQFEGCTVAWQRALADAGITLDDLSFVETHDCFTIAELIEYEAMG
HHHHHHCCCCCHHHHHEECCCHHHHHHHHHHCCCCHHCCCHHHHCCHHHHHHHHHHHHHC
LTTKGQGARAIKEGWTQKDGKLPINPSGGLKAKGHPIGATGVSMHVLTAMQLLGQAPEGM
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
QIKDAKLGGIFNMGGAAVANYVSVLEPAK
EEECCCCCCEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TASIVGWAHMPFGKFDAETVESMIVRVANEAIADAGIAAGDVDEIVLGHFNAGFSPQDF
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCC
TAALVLQADPALRFKPATRVENACATGSAAVHQGIRAIEAGAAKVVLVVGVEQMTRTPGP
EEEEEEECCCCCEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCH
EIGKNLLRASYLPEDGETPAGFAGVFGIIAQRYFQKYGDQSDALAMIAAKNHHNGVANPY
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHH
AQMRKDFGFEFCRAEGEKNPFVAGPLKRTDCSLVSDGAAALVLTSAENAKTMGKAVNIRA
HHHHHHHCHHHHHCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEEE
RAHAQDFLPMSKRDILQFEGCTVAWQRALADAGITLDDLSFVETHDCFTIAELIEYEAMG
HHHHHHCCCCCHHHHHEECCCHHHHHHHHHHCCCCHHCCCHHHHCCHHHHHHHHHHHHHC
LTTKGQGARAIKEGWTQKDGKLPINPSGGLKAKGHPIGATGVSMHVLTAMQLLGQAPEGM
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
QIKDAKLGGIFNMGGAAVANYVSVLEPAK
EEECCCCCCEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]