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The map label for this gene is ppaX [H]

Identifier: 86749186

GI number: 86749186

Start: 2347371

End: 2348021

Strand: Direct

Name: ppaX [H]

Synonym: RPB_2065

Alternate gene names: 86749186

Gene position: 2347371-2348021 (Clockwise)

Preceding gene: 86749185

Following gene: 86749187

Centisome position: 44.03

GC content: 73.12

Gene sequence:

>651_bases
ATGACCGCGGTGCTGTTCGATCTCGACGGCGTGCTGATCGATAGCTGGCAGGCGGTGGAAGCCGCCTTCCTCGCAGCCGC
GGCCGACCACGCGCTCGACGGCCGCGCCCGGCTGTCCGACTTTCGCGCGCGGATGGGAATGCCGCTGGAAGCGATCGTCG
CCGAGTTCGGCTTTCCCTCGGGCTTCCCCGCGGCGTTTCGCGCCGCCGCGCGTCTCCACGATCCCAAGGCCCGCGCATTT
CCCGGCGTCGTGGCGATGTTGCAGCACATCCGCAGCGCCGGATTGAAGCTCGGCGTGGTGACCGGGAAGGATCGGCCGCG
TACGCTGTCGATCCTCGCCGCCACCGGCCTGATCGAGCTGGTCGACGCGGTCGTCACCGCCGACGATGCGCCGGGCAAGC
CCGCGCCCGACGGGCTGTGGCTGTGCGAGCGCCGGCTCGGCGCCGGCGCGGCGCTGGCCTTCGTCGGCGACACCGCGATC
GATCTGGCCGCCGCGCGCAATGCCGGGCGCATCGCGATGCTGGCGCATTGGGGCGGCGGCCCGCAGGTCACGGATCGCGC
CGGCGTTATCGAGGTCGCAACGCCCGGCGAGGTCACCGACCTCGTCGTCGCGCTGGCGCAGGAGGCCCGCCGGCTGGAGC
CGGCGCGATGA

Upstream 100 bases:

>100_bases
TCGACGGCGGCGGCGCTGCAGTGAAAATCGACGACGTGTTCGCCGAGATCGCCGGATCGTCGCGCGCCGGCGCGAGCGCG
ATCGCGCAGGCGGCCGCGTC

Downstream 100 bases:

>100_bases
CGGCGCCGCTGCGGCAGGAACCGCTGCGGCTCGGCCTGTGCGGCTGCGGCTGGGTGATCCGGCATTGCTATCAGCCGGCG
CTGGCGGAGCTTTCGGCGCT

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTAVLFDLDGVLIDSWQAVEAAFLAAAADHALDGRARLSDFRARMGMPLEAIVAEFGFPSGFPAAFRAAARLHDPKARAF
PGVVAMLQHIRSAGLKLGVVTGKDRPRTLSILAATGLIELVDAVVTADDAPGKPAPDGLWLCERRLGAGAALAFVGDTAI
DLAAARNAGRIAMLAHWGGGPQVTDRAGVIEVATPGEVTDLVVALAQEARRLEPAR

Sequences:

>Translated_216_residues
MTAVLFDLDGVLIDSWQAVEAAFLAAAADHALDGRARLSDFRARMGMPLEAIVAEFGFPSGFPAAFRAAARLHDPKARAF
PGVVAMLQHIRSAGLKLGVVTGKDRPRTLSILAATGLIELVDAVVTADDAPGKPAPDGLWLCERRLGAGAALAFVGDTAI
DLAAARNAGRIAMLAHWGGGPQVTDRAGVIEVATPGEVTDLVVALAQEARRLEPAR
>Mature_215_residues
TAVLFDLDGVLIDSWQAVEAAFLAAAADHALDGRARLSDFRARMGMPLEAIVAEFGFPSGFPAAFRAAARLHDPKARAFP
GVVAMLQHIRSAGLKLGVVTGKDRPRTLSILAATGLIELVDAVVTADDAPGKPAPDGLWLCERRLGAGAALAFVGDTAID
LAAARNAGRIAMLAHWGGGPQVTDRAGVIEVATPGEVTDLVVALAQEARRLEPAR

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 22476; Mature: 22345

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVLFDLDGVLIDSWQAVEAAFLAAAADHALDGRARLSDFRARMGMPLEAIVAEFGFPS
CEEEEEECCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
GFPAAFRAAARLHDPKARAFPGVVAMLQHIRSAGLKLGVVTGKDRPRTLSILAATGLIEL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHHHHH
VDAVVTADDAPGKPAPDGLWLCERRLGAGAALAFVGDTAIDLAAARNAGRIAMLAHWGGG
HHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCC
PQVTDRAGVIEVATPGEVTDLVVALAQEARRLEPAR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAVLFDLDGVLIDSWQAVEAAFLAAAADHALDGRARLSDFRARMGMPLEAIVAEFGFPS
EEEEEECCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
GFPAAFRAAARLHDPKARAFPGVVAMLQHIRSAGLKLGVVTGKDRPRTLSILAATGLIEL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHHHHH
VDAVVTADDAPGKPAPDGLWLCERRLGAGAALAFVGDTAIDLAAARNAGRIAMLAHWGGG
HHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCC
PQVTDRAGVIEVATPGEVTDLVVALAQEARRLEPAR
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA