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The map label for this gene is patA [H]

Identifier: 86748854

GI number: 86748854

Start: 1975885

End: 1977276

Strand: Direct

Name: patA [H]

Synonym: RPB_1731

Alternate gene names: 86748854

Gene position: 1975885-1977276 (Clockwise)

Preceding gene: 86748853

Following gene: 86748855

Centisome position: 37.06

GC content: 64.94

Gene sequence:

>1392_bases
ATGCCATATCCCCATATCGACGTCGCCGCGCTCTTCGCCGACCGCGAGTCCGAGCGGAGCGCAATGCATACGCGCAACCT
CAACGAGCAGCTCGTGCGCGTGCTCAAGACGATCGGCTACGATGTCGGGTTCCAGAAGGGAAGCGGGCAGTATCTTTACG
ATCGGGACGGTGCCCGTTATCTCGATCTGCTCAGTGGCTTCGGCGTTTTCGCGCTCGGCCGCAATCATCCGGCGCTGCGC
GACGCGCTGAAGAGCGTGCTCGACGGCGAACTGCCGAACCTGGTGCAGCTCGACGTCTCGACCTTGGCCGGCGTGCTCGC
CGAGCGCCTGTTGGAGCTCGTGCCCTATCTCGACAAGGTCTTCTTCGCCAATTCCGGAGCCGAGAGCGTCGAGGCTGCGA
TCAAATTCGCCCGCAACGCCACCGGGCGCCAGGGCATCGTCAACTGCGACCACAGCTATCACGGCCTGACCTATGGCGCG
CTGTCGCTGACCGACGACCAGAATTTTCAGGGCGGCTTCGGGCCGCTGTTGCCCGGCGTTACCACGATCCCGTTCAACGA
TCTCGAAGCACTGGAGAAGGCGCTGTCGACCCGCGAGGTCGCGGCCTTCATCGTCGAGCCGATCCAGGGCAAGGGCGTCA
ACATGCCCAGCGACGAGTTCCTGCCGGGTGCGGCGGCGCTGTGCAAGCGCTACGGCACGCTGTTCGTCGCCGACGAGATC
CAGACCGGCATGGGCCGCACCGGCCGCTTCCTCGCGGTCGAGCACTGGAACGTTGAGCCCGACATGGTGCTGTTGTCGAA
GGCACTGAGCGGCGGCCATGTCCCGGTCGGCGCGGTGCTGACGCGCAGGGCGATCTTCGACAAGATCTTCAACCGGATGG
ATCGCGCCGTGGTGCACGGCTCGACCTTCGCCAAGAACGATCTGGCGATGGCCGCCGGCATCGCTACGCTCGACGTGATG
AAGCACGAGAAGCTGATCGAGGCCGCCGCCAAGCGCGGCGCCGAGCTGCGGCTGGCGCTCAGCGGCATGATCCCGGGCTA
CGAACTTCTCAAAGACGTCCGCGGCAAGGGGCTGATGATCGGCGTCGAATTCGGCCCGCCGAAATCAATGCGGCTGAAGG
CGTCGTGGGCCATGCTGGAGACCGCCAACAAGGGTCTGTTCGTTCAGCTGATCACCGTGCCGCTGTTCAAGGATCACAAG
ATCCTGACGCAGGTCGCGGGCCACGGTTTGCACACCATCAAGCTGCTGCCGCCGCTGACGATCACCGAGGACGACTGCAA
GTGGATCGTGCGCGGCTTCGACGAAGCGATCGCCGCCAGCCACAAGGTCCCCGGCGCGATCTGGTCGCTCGGCAAGACCT
TGGTCGACAACGCGGTGCGCAAGTCGGCGTGA

Upstream 100 bases:

>100_bases
TTCGCGCGGCGGCCGTAGCCTCCGTCTCGACGCACGGGTCAAAGCGCCGCAACCCGCGTTTTGGGTTGACGACGCGCCCA
ACAACCGACGTAAGTAGCCA

Downstream 100 bases:

>100_bases
TCTGAAACCCGCCCACGCGGGCGCGTCAGGGCGCCGCATGCGGCCTGCGCAGCTTGACCTGAAGCAAGTCTGTCGCGATC
TGTTCTGCCTATCTTCGCTC

Product: aminotransferase class-III

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MPYPHIDVAALFADRESERSAMHTRNLNEQLVRVLKTIGYDVGFQKGSGQYLYDRDGARYLDLLSGFGVFALGRNHPALR
DALKSVLDGELPNLVQLDVSTLAGVLAERLLELVPYLDKVFFANSGAESVEAAIKFARNATGRQGIVNCDHSYHGLTYGA
LSLTDDQNFQGGFGPLLPGVTTIPFNDLEALEKALSTREVAAFIVEPIQGKGVNMPSDEFLPGAAALCKRYGTLFVADEI
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGAVLTRRAIFDKIFNRMDRAVVHGSTFAKNDLAMAAGIATLDVM
KHEKLIEAAAKRGAELRLALSGMIPGYELLKDVRGKGLMIGVEFGPPKSMRLKASWAMLETANKGLFVQLITVPLFKDHK
ILTQVAGHGLHTIKLLPPLTITEDDCKWIVRGFDEAIAASHKVPGAIWSLGKTLVDNAVRKSA

Sequences:

>Translated_463_residues
MPYPHIDVAALFADRESERSAMHTRNLNEQLVRVLKTIGYDVGFQKGSGQYLYDRDGARYLDLLSGFGVFALGRNHPALR
DALKSVLDGELPNLVQLDVSTLAGVLAERLLELVPYLDKVFFANSGAESVEAAIKFARNATGRQGIVNCDHSYHGLTYGA
LSLTDDQNFQGGFGPLLPGVTTIPFNDLEALEKALSTREVAAFIVEPIQGKGVNMPSDEFLPGAAALCKRYGTLFVADEI
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGAVLTRRAIFDKIFNRMDRAVVHGSTFAKNDLAMAAGIATLDVM
KHEKLIEAAAKRGAELRLALSGMIPGYELLKDVRGKGLMIGVEFGPPKSMRLKASWAMLETANKGLFVQLITVPLFKDHK
ILTQVAGHGLHTIKLLPPLTITEDDCKWIVRGFDEAIAASHKVPGAIWSLGKTLVDNAVRKSA
>Mature_462_residues
PYPHIDVAALFADRESERSAMHTRNLNEQLVRVLKTIGYDVGFQKGSGQYLYDRDGARYLDLLSGFGVFALGRNHPALRD
ALKSVLDGELPNLVQLDVSTLAGVLAERLLELVPYLDKVFFANSGAESVEAAIKFARNATGRQGIVNCDHSYHGLTYGAL
SLTDDQNFQGGFGPLLPGVTTIPFNDLEALEKALSTREVAAFIVEPIQGKGVNMPSDEFLPGAAALCKRYGTLFVADEIQ
TGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGAVLTRRAIFDKIFNRMDRAVVHGSTFAKNDLAMAAGIATLDVMK
HEKLIEAAAKRGAELRLALSGMIPGYELLKDVRGKGLMIGVEFGPPKSMRLKASWAMLETANKGLFVQLITVPLFKDHKI
LTQVAGHGLHTIKLLPPLTITEDDCKWIVRGFDEAIAASHKVPGAIWSLGKTLVDNAVRKSA

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=406, Percent_Identity=37.4384236453202, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI284507298, Length=313, Percent_Identity=39.297124600639, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=28.8636363636364, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=27.6029055690073, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=27.710843373494, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=26.9417475728155, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=27.1099744245524, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI188536080, Length=447, Percent_Identity=25.2796420581655, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=447, Percent_Identity=25.2796420581655, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=447, Percent_Identity=25.2796420581655, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI145693181, Length=417, Percent_Identity=35.2517985611511, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789759, Length=336, Percent_Identity=34.8214285714286, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=31.0945273631841, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=30.9823677581864, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786349, Length=304, Percent_Identity=35.1973684210526, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1789016, Length=411, Percent_Identity=27.9805352798054, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1786991, Length=347, Percent_Identity=32.8530259365994, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=332, Percent_Identity=37.3493975903614, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI25144274, Length=322, Percent_Identity=33.2298136645963, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=31.0185185185185, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=26.8518518518519, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=410, Percent_Identity=26.0975609756098, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=30.379746835443, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323470, Length=421, Percent_Identity=33.0166270783848, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324432, Length=420, Percent_Identity=30.4761904761905, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=323, Percent_Identity=27.5541795665635, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=34.2710997442455, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=31.1059907834101, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=31.8501170960187, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21356575, Length=468, Percent_Identity=26.2820512820513, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281366494, Length=400, Percent_Identity=27, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667139, Length=400, Percent_Identity=27, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667143, Length=400, Percent_Identity=27, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 50285; Mature: 50154

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYPHIDVAALFADRESERSAMHTRNLNEQLVRVLKTIGYDVGFQKGSGQYLYDRDGARY
CCCCCCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHH
LDLLSGFGVFALGRNHPALRDALKSVLDGELPNLVQLDVSTLAGVLAERLLELVPYLDKV
HHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
FFANSGAESVEAAIKFARNATGRQGIVNCDHSYHGLTYGALSLTDDQNFQGGFGPLLPGV
HHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
TTIPFNDLEALEKALSTREVAAFIVEPIQGKGVNMPSDEFLPGAAALCKRYGTLFVADEI
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEHHH
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGAVLTRRAIFDKIFNRMDRAVVHG
HHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
STFAKNDLAMAAGIATLDVMKHEKLIEAAAKRGAELRLALSGMIPGYELLKDVRGKGLMI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCEEEE
GVEFGPPKSMRLKASWAMLETANKGLFVQLITVPLFKDHKILTQVAGHGLHTIKLLPPLT
EEEECCCCCEEEEEHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCE
ITEDDCKWIVRGFDEAIAASHKVPGAIWSLGKTLVDNAVRKSA
ECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PYPHIDVAALFADRESERSAMHTRNLNEQLVRVLKTIGYDVGFQKGSGQYLYDRDGARY
CCCCCCHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHH
LDLLSGFGVFALGRNHPALRDALKSVLDGELPNLVQLDVSTLAGVLAERLLELVPYLDKV
HHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
FFANSGAESVEAAIKFARNATGRQGIVNCDHSYHGLTYGALSLTDDQNFQGGFGPLLPGV
HHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
TTIPFNDLEALEKALSTREVAAFIVEPIQGKGVNMPSDEFLPGAAALCKRYGTLFVADEI
EECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEHHH
QTGMGRTGRFLAVEHWNVEPDMVLLSKALSGGHVPVGAVLTRRAIFDKIFNRMDRAVVHG
HHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
STFAKNDLAMAAGIATLDVMKHEKLIEAAAKRGAELRLALSGMIPGYELLKDVRGKGLMI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCEEEE
GVEFGPPKSMRLKASWAMLETANKGLFVQLITVPLFKDHKILTQVAGHGLHTIKLLPPLT
EEEECCCCCEEEEEHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCE
ITEDDCKWIVRGFDEAIAASHKVPGAIWSLGKTLVDNAVRKSA
ECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA