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The map label for this gene is exbB [H]

Identifier: 86748778

GI number: 86748778

Start: 1885251

End: 1886111

Strand: Direct

Name: exbB [H]

Synonym: RPB_1655

Alternate gene names: 86748778

Gene position: 1885251-1886111 (Clockwise)

Preceding gene: 86748777

Following gene: 86748779

Centisome position: 35.36

GC content: 68.18

Gene sequence:

>861_bases
ATGAATGTTGTGATGCGGCGGTTCGCTTTGGGGGCGATATTCGTGCTGGTCCATCTGCCGGCCGCAGCGCAGGAGGCGAC
CCCGGCCGTCGAGGCGCCGGTGCCGCTGTCTCCGCCGGCGATCGCGGTGCCCACCAACTTGCCGCACGATCTGTCACCCT
GGGCGATGTTTGTTGCCGCCGACAATATCGTCAAGGCGGTGATCATCGGGCTGGCGCTCGCCTCGCTGGCAACCTGGACG
GTGTGGCTGGTCAAGGTCATCGAACTGACGAGCGCGCTGCGCAAGGCGCGTAGCGCGCTGCGCAAGCTGCAGCGCGCAGA
CAATCTGGCCGACGCAACGCGCGAGATCGAGGCCGAGTGGACCAAGGACGGTCCCGTCGCCGATCTGGTTCAGGCAGCAC
TGCGCGAGACCGAGCGGTCGGTCGATCTCGCGGCCGACGGCGTGAAGGAGCGGCTCGCCATCGCGCTGTCGCGGATCGAG
GCCAGGGCCGGCCGCGACATGGCACGATCGACCGGGCTGCTCGCGACCATCGGGGCGACCGCGCCGTTCATCGGCCTGTT
CGGCACGGTGTGGGGTATCATGAATTCGTTCATCGGCATCGCGCAGTCGAAGACCACCAATCTGGCGGTCGTGGCCCCGG
GCATCGCCGAAGCGCTGCTCGCCACCGCGATCGGCCTGGTCGCGGCGATTCCGGCGGTGATCATCTACAACGTGTTCGCG
CGTGCCATCGCCGGCTATCGCGCGCTGTTGTCGGATGCGTCCGGCGAAGTGCTGCAGCACCTGTCGCGCGATCTGGAACG
GCAGCAGAAGCCTGTCGTCAGCCGCGCCGCGCCTGCGCGCTCGCGCTGGATGGCGGAGTAG

Upstream 100 bases:

>100_bases
GGAGCTTGCGATGCAGGAATGCCAGTGACTGCGCATCAATTTTTGCCATGATCGGCCGCGCTTTTTGACGGGGCGGGTCG
AACGAAAGAGGCGTTTCGGA

Downstream 100 bases:

>100_bases
CCGACCATGGCGGTGACGCTGAAGGATCCGCACGACGGCGACCTCGCCGAACTGTCCGAAATCAACGTGACGCCGTTCAT
CGACGTGATGCTGGTGCTGC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNVVMRRFALGAIFVLVHLPAAAQEATPAVEAPVPLSPPAIAVPTNLPHDLSPWAMFVAADNIVKAVIIGLALASLATWT
VWLVKVIELTSALRKARSALRKLQRADNLADATREIEAEWTKDGPVADLVQAALRETERSVDLAADGVKERLAIALSRIE
ARAGRDMARSTGLLATIGATAPFIGLFGTVWGIMNSFIGIAQSKTTNLAVVAPGIAEALLATAIGLVAAIPAVIIYNVFA
RAIAGYRALLSDASGEVLQHLSRDLERQQKPVVSRAAPARSRWMAE

Sequences:

>Translated_286_residues
MNVVMRRFALGAIFVLVHLPAAAQEATPAVEAPVPLSPPAIAVPTNLPHDLSPWAMFVAADNIVKAVIIGLALASLATWT
VWLVKVIELTSALRKARSALRKLQRADNLADATREIEAEWTKDGPVADLVQAALRETERSVDLAADGVKERLAIALSRIE
ARAGRDMARSTGLLATIGATAPFIGLFGTVWGIMNSFIGIAQSKTTNLAVVAPGIAEALLATAIGLVAAIPAVIIYNVFA
RAIAGYRALLSDASGEVLQHLSRDLERQQKPVVSRAAPARSRWMAE
>Mature_286_residues
MNVVMRRFALGAIFVLVHLPAAAQEATPAVEAPVPLSPPAIAVPTNLPHDLSPWAMFVAADNIVKAVIIGLALASLATWT
VWLVKVIELTSALRKARSALRKLQRADNLADATREIEAEWTKDGPVADLVQAALRETERSVDLAADGVKERLAIALSRIE
ARAGRDMARSTGLLATIGATAPFIGLFGTVWGIMNSFIGIAQSKTTNLAVVAPGIAEALLATAIGLVAAIPAVIIYNVFA
RAIAGYRALLSDASGEVLQHLSRDLERQQKPVVSRAAPARSRWMAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=223, Percent_Identity=52.914798206278, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI1786958, Length=191, Percent_Identity=34.0314136125654, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30343; Mature: 30343

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVVMRRFALGAIFVLVHLPAAAQEATPAVEAPVPLSPPAIAVPTNLPHDLSPWAMFVAA
CCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHH
DNIVKAVIIGLALASLATWTVWLVKVIELTSALRKARSALRKLQRADNLADATREIEAEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKDGPVADLVQAALRETERSVDLAADGVKERLAIALSRIEARAGRDMARSTGLLATIGAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCH
APFIGLFGTVWGIMNSFIGIAQSKTTNLAVVAPGIAEALLATAIGLVAAIPAVIIYNVFA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIAGYRALLSDASGEVLQHLSRDLERQQKPVVSRAAPARSRWMAE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCC
>Mature Secondary Structure
MNVVMRRFALGAIFVLVHLPAAAQEATPAVEAPVPLSPPAIAVPTNLPHDLSPWAMFVAA
CCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHH
DNIVKAVIIGLALASLATWTVWLVKVIELTSALRKARSALRKLQRADNLADATREIEAEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKDGPVADLVQAALRETERSVDLAADGVKERLAIALSRIEARAGRDMARSTGLLATIGAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCH
APFIGLFGTVWGIMNSFIGIAQSKTTNLAVVAPGIAEALLATAIGLVAAIPAVIIYNVFA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIAGYRALLSDASGEVLQHLSRDLERQQKPVVSRAAPARSRWMAE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]