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The map label for this gene is arsR [H]

Identifier: 86748767

GI number: 86748767

Start: 1874374

End: 1874667

Strand: Direct

Name: arsR [H]

Synonym: RPB_1644

Alternate gene names: 86748767

Gene position: 1874374-1874667 (Clockwise)

Preceding gene: 86748766

Following gene: 86748768

Centisome position: 35.16

GC content: 63.95

Gene sequence:

>294_bases
ATGGATCCGATCGATATCTTGTCGGCGCTGGCCGAGGAAACGCGGCTCGAGGCCTTGCGGCTCCTGTGGGACGGGCAGGA
ACACTGTGTCTGTGAACTGATGAAGAGGCTCGGTGCCTCCCAATCGCGGATGTCGCGGCATATGGGGGTGCTGAAGGTCG
CCGGTCTGGTGATCGATCGCCGCGACGCGCAGTGGGTTCGCTACCGGCGCAATCCAAATCTGGATCCGAAAATTATCGCC
GTGGTCGAGGCCGTGCTGGCGCTTCCGGCGCGCGACAGGAGGGCGGCCGCATGA

Upstream 100 bases:

>100_bases
AGAAAGCCGTATGAGATTGAGATGGATCAATACATTATGCGTATATGCGCATATACGCATTTTTTCGGCGGAGTCTTGAA
CGGCGCGCAGCGGGGCGAGG

Downstream 100 bases:

>100_bases
CGACTTTAGAGAGCAAAGTCGGGCAGGAGCCACGGACCGCCGTCTGGCTGGCCGGAACGGCGGCATTTCTGGTGGCCTGG
GGCCTGATCTACGCGCAACT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MDPIDILSALAEETRLEALRLLWDGQEHCVCELMKRLGASQSRMSRHMGVLKVAGLVIDRRDAQWVRYRRNPNLDPKIIA
VVEAVLALPARDRRAAA

Sequences:

>Translated_97_residues
MDPIDILSALAEETRLEALRLLWDGQEHCVCELMKRLGASQSRMSRHMGVLKVAGLVIDRRDAQWVRYRRNPNLDPKIIA
VVEAVLALPARDRRAAA
>Mature_97_residues
MDPIDILSALAEETRLEALRLLWDGQEHCVCELMKRLGASQSRMSRHMGVLKVAGLVIDRRDAQWVRYRRNPNLDPKIIA
VVEAVLALPARDRRAAA

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=72, Percent_Identity=43.0555555555556, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 10987; Mature: 10987

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPIDILSALAEETRLEALRLLWDGQEHCVCELMKRLGASQSRMSRHMGVLKVAGLVIDR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
RDAQWVRYRRNPNLDPKIIAVVEAVLALPARDRRAAA
CCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDPIDILSALAEETRLEALRLLWDGQEHCVCELMKRLGASQSRMSRHMGVLKVAGLVIDR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
RDAQWVRYRRNPNLDPKIIAVVEAVLALPARDRRAAA
CCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]