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The map label for this gene is hcaT [H]

Identifier: 86748749

GI number: 86748749

Start: 1831357

End: 1832559

Strand: Direct

Name: hcaT [H]

Synonym: RPB_1625

Alternate gene names: 86748749

Gene position: 1831357-1832559 (Clockwise)

Preceding gene: 86748747

Following gene: 86748751

Centisome position: 34.35

GC content: 68.83

Gene sequence:

>1203_bases
ATGTCTCCCGAATCACAAATCCCCACCAGAACAAGGGCTCCGAAGCGATTCGCGATCGGGCTCGCGGTATTCTATGCGAC
GGTGTTCGGCGTCGTCGGGACCTATCTGCCCTTCTTCACCGTATGGCTGAAAGCGATCGGGATCGAGCCCTTCTGGATCG
GCGTGATCGTGGCGATGCCGGCGATCACCCGCTTCACGGTGCTGCCGTTCATCACCGCGGAGGCGGAGCGGCGCCACGCG
CTGCGACCGGCACTTGTTATCACAGCCATCGTCACCACGCTCGGCTTTGTCTGCCTCGGGGTGCTACGAGGCCCGCTGGC
GATTCTCGCGGTGTTCGTGGTCACCGCCTGTGCCTGGACGCCGATGGTGCCGCTGACCGACGGCTACGCGCTGAAGGCGG
TGAGGCGGTTCGGCCTGAACTACGGGCCGCTGCGATTGTGGGGCTCCGCCGCCTTCGTCGTCGGGGCGGTGGTGAGCGGC
GTGCTGGCCGACATCATCGCACCCGAGCATCTGATCTGGGTGATCGCGGCCTCCGCCGGACTCGGCGTGATCGCCGCCTT
CGGATTGCAGCCGCTCGACGCCCCGGGCGCGCACCCGGCGCCGCCCGCGCGCCGGGTGGCGTTGCTGCGCAACCCGGCCT
TTCTGGCGATCATCATTGCCGGCGGGCTGATCCAGGGCAGCCATGCGGCGTACTACGCGTTCGGCTCGATCGTCTGGCAG
GGGGCGGGCTACAGCGGCATGACGATCGCGAGCCTGTGGATCCTCGGCGTGCTCGCCGAGATCGTGGTGTTCGCGCTGTC
GCCGCGCATCACGCTGTCGCCGGCGCTGATGATGCTGGGCGGCGCGCTCGGTGCCGTGCTGCGCTGGCTGATCACCGCGC
AGGATCCGCCGCTCGCCGTTCTCCTCCCGGTGCAGTTGCTGCACGGGTTGAGCTTCGGGCTGACGCAACTCGGCACCATG
GGGCTGCTGGTGCGCCACGCCCCGGGTCATCTCATCGCCCGGGCGCAGGGCTACTACGCGGCCTGTTCAGGTCTGGCGAT
GAGCAGCGCCGCGATGCTCTCCGGCCTGCTGTTCGCGCGCTGGGGCCTCGCCGTCTACGATCTGATGGCGGCGGTGGCGC
TGATCGGCGCGGTGGTGGTCGTTGCGATGCGTCGCCGCCTCGACACGCACGATCAGCCCCACAACGAGGGCTCCGGCGGA
TAG

Upstream 100 bases:

>100_bases
ACAGTGCGAATGCTTCTTCGGCCATCAGGGACTCATTGCGCAAATCGCTGCGCGTCACGATAACGATCACCACGAACCGT
GCTGAATCGCAATTGAATTG

Downstream 100 bases:

>100_bases
ACGATGCTGCCGTCGTAGCGCAGGCCGTCGTCGCGATCCTTCGCCAGCAGCAGCGGGCCGTCGAGATCGACGAAGCGGGC
GTGCGGCGTCAGCAGCATCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSPESQIPTRTRAPKRFAIGLAVFYATVFGVVGTYLPFFTVWLKAIGIEPFWIGVIVAMPAITRFTVLPFITAEAERRHA
LRPALVITAIVTTLGFVCLGVLRGPLAILAVFVVTACAWTPMVPLTDGYALKAVRRFGLNYGPLRLWGSAAFVVGAVVSG
VLADIIAPEHLIWVIAASAGLGVIAAFGLQPLDAPGAHPAPPARRVALLRNPAFLAIIIAGGLIQGSHAAYYAFGSIVWQ
GAGYSGMTIASLWILGVLAEIVVFALSPRITLSPALMMLGGALGAVLRWLITAQDPPLAVLLPVQLLHGLSFGLTQLGTM
GLLVRHAPGHLIARAQGYYAACSGLAMSSAAMLSGLLFARWGLAVYDLMAAVALIGAVVVVAMRRRLDTHDQPHNEGSGG

Sequences:

>Translated_400_residues
MSPESQIPTRTRAPKRFAIGLAVFYATVFGVVGTYLPFFTVWLKAIGIEPFWIGVIVAMPAITRFTVLPFITAEAERRHA
LRPALVITAIVTTLGFVCLGVLRGPLAILAVFVVTACAWTPMVPLTDGYALKAVRRFGLNYGPLRLWGSAAFVVGAVVSG
VLADIIAPEHLIWVIAASAGLGVIAAFGLQPLDAPGAHPAPPARRVALLRNPAFLAIIIAGGLIQGSHAAYYAFGSIVWQ
GAGYSGMTIASLWILGVLAEIVVFALSPRITLSPALMMLGGALGAVLRWLITAQDPPLAVLLPVQLLHGLSFGLTQLGTM
GLLVRHAPGHLIARAQGYYAACSGLAMSSAAMLSGLLFARWGLAVYDLMAAVALIGAVVVVAMRRRLDTHDQPHNEGSGG
>Mature_399_residues
SPESQIPTRTRAPKRFAIGLAVFYATVFGVVGTYLPFFTVWLKAIGIEPFWIGVIVAMPAITRFTVLPFITAEAERRHAL
RPALVITAIVTTLGFVCLGVLRGPLAILAVFVVTACAWTPMVPLTDGYALKAVRRFGLNYGPLRLWGSAAFVVGAVVSGV
LADIIAPEHLIWVIAASAGLGVIAAFGLQPLDAPGAHPAPPARRVALLRNPAFLAIIIAGGLIQGSHAAYYAFGSIVWQG
AGYSGMTIASLWILGVLAEIVVFALSPRITLSPALMMLGGALGAVLRWLITAQDPPLAVLLPVQLLHGLSFGLTQLGTMG
LLVRHAPGHLIARAQGYYAACSGLAMSSAAMLSGLLFARWGLAVYDLMAAVALIGAVVVVAMRRRLDTHDQPHNEGSGG

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=366, Percent_Identity=34.6994535519126, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 42035; Mature: 41903

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPESQIPTRTRAPKRFAIGLAVFYATVFGVVGTYLPFFTVWLKAIGIEPFWIGVIVAMP
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AITRFTVLPFITAEAERRHALRPALVITAIVTTLGFVCLGVLRGPLAILAVFVVTACAWT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMVPLTDGYALKAVRRFGLNYGPLRLWGSAAFVVGAVVSGVLADIIAPEHLIWVIAASAG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCC
LGVIAAFGLQPLDAPGAHPAPPARRVALLRNPAFLAIIIAGGLIQGSHAAYYAFGSIVWQ
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEHEECCCCCCCCCHHHHHHHHHHCC
GAGYSGMTIASLWILGVLAEIVVFALSPRITLSPALMMLGGALGAVLRWLITAQDPPLAV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LLPVQLLHGLSFGLTQLGTMGLLVRHAPGHLIARAQGYYAACSGLAMSSAAMLSGLLFAR
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHH
WGLAVYDLMAAVALIGAVVVVAMRRRLDTHDQPHNEGSGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SPESQIPTRTRAPKRFAIGLAVFYATVFGVVGTYLPFFTVWLKAIGIEPFWIGVIVAMP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AITRFTVLPFITAEAERRHALRPALVITAIVTTLGFVCLGVLRGPLAILAVFVVTACAWT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMVPLTDGYALKAVRRFGLNYGPLRLWGSAAFVVGAVVSGVLADIIAPEHLIWVIAASAG
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCC
LGVIAAFGLQPLDAPGAHPAPPARRVALLRNPAFLAIIIAGGLIQGSHAAYYAFGSIVWQ
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEHEECCCCCCCCCHHHHHHHHHHCC
GAGYSGMTIASLWILGVLAEIVVFALSPRITLSPALMMLGGALGAVLRWLITAQDPPLAV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LLPVQLLHGLSFGLTQLGTMGLLVRHAPGHLIARAQGYYAACSGLAMSSAAMLSGLLFAR
EHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHH
WGLAVYDLMAAVALIGAVVVVAMRRRLDTHDQPHNEGSGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]