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The map label for this gene is neuA [H]

Identifier: 86748661

GI number: 86748661

Start: 1730181

End: 1730876

Strand: Direct

Name: neuA [H]

Synonym: RPB_1536

Alternate gene names: 86748661

Gene position: 1730181-1730876 (Clockwise)

Preceding gene: 86748660

Following gene: 86748662

Centisome position: 32.45

GC content: 66.38

Gene sequence:

>696_bases
ATGACGCTCGCTGCTGTCATCCCGGCACGCGGCGGGTCGAAGGGCATCCCGCGTAAGAATCTCGCGCTGTGCGGCGACCG
TTCGCTGCTCGCCTGGACCGCGCAGGCCGCGCTGGAGTCGCAGGTGATCGACGTCGCCATGCTCTCGACGGATGACGATG
AGATCGCCGACGCGGGCAGGGCGCTGGGGCTGGACGTGCCGTTCAGGCGACCGGCCGAGTTGGCCGGGGACGCGGCCCCG
ATGCTCGGGGTGATGCAGCACTGCCTCGCCCATCTGCGCCGTGACGGCACGGACGTCGAGGCGCTCGTCTTGCTGCAGCC
GACGTCGCCATTCCGCCGCGCCCATCATGTCCGGGAAGCAGTCCAGAGATTTCGCGCCGGCCAGGCGGCGACCCTGGTCA
GCCTCGTGAGGGTCCCCCATCGCTTCGTGCCCGAAGGTCAAATGCGCGAGCAGGGTGGCGAGGTGGTCCCGTATTTCGGC
GGCGATATCGGAAAGACGCGACGTCAGGACAAGGAGGTGCTGTTCGGTAGAAACGGGCCGGCCATCCTGATCGTGCGCGC
ATCCGTTCTCGACTCGGGCAGTCTCTACGGCCATCCGACGATCGGCTTTGAAATGGACGAAATTTCGTCGATCGACATCG
ATGCGCCGGAAGACCTCAGGCTCGCGGATCATCTGTTGCGAACGGGCTATGCGTGA

Upstream 100 bases:

>100_bases
GCGGGCACGAAGATCGCCGACATACTCGTCACGGAGAGGGTGGACGTCCAAAAGTGTATCACCTATTGAGTCACGGCCTC
CGGACGCGGACGCTGGTGAG

Downstream 100 bases:

>100_bases
TGTCGCGATTGTTCGAGATGCTTCGCCGCACGCCGTTGGCCGGTCCGGTTGCGGACATCGCCAGCGTCGTGAGACCACCC
CATGGCGGGCTGAAGCTGTG

Product: acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTLAAVIPARGGSKGIPRKNLALCGDRSLLAWTAQAALESQVIDVAMLSTDDDEIADAGRALGLDVPFRRPAELAGDAAP
MLGVMQHCLAHLRRDGTDVEALVLLQPTSPFRRAHHVREAVQRFRAGQAATLVSLVRVPHRFVPEGQMREQGGEVVPYFG
GDIGKTRRQDKEVLFGRNGPAILIVRASVLDSGSLYGHPTIGFEMDEISSIDIDAPEDLRLADHLLRTGYA

Sequences:

>Translated_231_residues
MTLAAVIPARGGSKGIPRKNLALCGDRSLLAWTAQAALESQVIDVAMLSTDDDEIADAGRALGLDVPFRRPAELAGDAAP
MLGVMQHCLAHLRRDGTDVEALVLLQPTSPFRRAHHVREAVQRFRAGQAATLVSLVRVPHRFVPEGQMREQGGEVVPYFG
GDIGKTRRQDKEVLFGRNGPAILIVRASVLDSGSLYGHPTIGFEMDEISSIDIDAPEDLRLADHLLRTGYA
>Mature_230_residues
TLAAVIPARGGSKGIPRKNLALCGDRSLLAWTAQAALESQVIDVAMLSTDDDEIADAGRALGLDVPFRRPAELAGDAAPM
LGVMQHCLAHLRRDGTDVEALVLLQPTSPFRRAHHVREAVQRFRAGQAATLVSLVRVPHRFVPEGQMREQGGEVVPYFGG
DIGKTRRQDKEVLFGRNGPAILIVRASVLDSGSLYGHPTIGFEMDEISSIDIDAPEDLRLADHLLRTGYA

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=230, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 24976; Mature: 24845

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAAVIPARGGSKGIPRKNLALCGDRSLLAWTAQAALESQVIDVAMLSTDDDEIADAGR
CCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCC
ALGLDVPFRRPAELAGDAAPMLGVMQHCLAHLRRDGTDVEALVLLQPTSPFRRAHHVREA
EECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
VQRFRAGQAATLVSLVRVPHRFVPEGQMREQGGEVVPYFGGDIGKTRRQDKEVLFGRNGP
HHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCCEEEECCCCCCHHHHHCCCEEECCCCC
AILIVRASVLDSGSLYGHPTIGFEMDEISSIDIDAPEDLRLADHLLRTGYA
EEEEEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLAAVIPARGGSKGIPRKNLALCGDRSLLAWTAQAALESQVIDVAMLSTDDDEIADAGR
CEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCC
ALGLDVPFRRPAELAGDAAPMLGVMQHCLAHLRRDGTDVEALVLLQPTSPFRRAHHVREA
EECCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
VQRFRAGQAATLVSLVRVPHRFVPEGQMREQGGEVVPYFGGDIGKTRRQDKEVLFGRNGP
HHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCCEEEECCCCCCHHHHHCCCEEECCCCC
AILIVRASVLDSGSLYGHPTIGFEMDEISSIDIDAPEDLRLADHLLRTGYA
EEEEEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549035 [H]