Click here to switch to the map view.

The map label for this gene is 86748659

Identifier: 86748659

GI number: 86748659

Start: 1727997

End: 1728995

Strand: Direct

Name: 86748659

Synonym: RPB_1534

Alternate gene names: NA

Gene position: 1727997-1728995 (Clockwise)

Preceding gene: 86748658

Following gene: 86748660

Centisome position: 32.41

GC content: 61.26

Gene sequence:

>999_bases
ATGCCCGCAACAAGTAATCCGTATATCATTGCGGAAATCGGTTCGGTTCACGACGGGTCGTTCGGCAATGCCTGCCGTCT
GCTCGAGACCGCCGCAGAATGCGGGGCGGATGCGGTCAAGTTTCAGACCCATATCGCAGAGGCGGAAACGCTGCCGAACG
CGCCGTCGCCCTCCTACTTCTCGGCAGAGCCGCGCACTGCCTATTTCAAGCGGACCGGGTTCTCGCCCGAGCAGTGGCGC
GCGCTCGCGGCGCTCGCGAAATCAACGAAGGTCGACTTTTTGTCCTCGCCGTTCTCGCTCGAAGCGGTGGATCTGCTCGA
AGACGTCGGTGTCGCCGCCTACAAGATTCCCTCCGGCGAAGTCAGCAATATTCCCTTGCTCAGCCGCATCGCGCAGACCG
GAAAGCCGGTCTTTCTGTCGTCGGGCATGAGCAATTGGGAAGAGCTCGATGCGGCGGTCGGCGCCCTGCGCGGATCGGCG
CTCACCTTGTTGCAATGCACCTCCAAGTATCCCTGTCCGCCGGAGCAGGTGGGACTGAATGCGATGTGCGTCATGAGAGA
GCGCTATGGCATCCCCGTCGGCTATTCGGACCACACGCTCGGATTTGCGGCGCCAATCGCCGCCGTCGCCCTCGGCGCCA
CGGTGATCGAAAAGCACTTCACATTCTCCAAGCTGATGTACGGCAGCGATGCGAAGAACAGCATGGAGCCGGACGAGTTT
CGGCGGCTTTGCCGAGAGCTCAAGGAGACCGCCCGGATCATCGCCAGCCCGGTCGACAAGGACGATTTGTCGTCGCTGTC
CGACATGAAGCTGATCTTCGAGAAGAGCATCGTCTCGGCGACCGATCTGCCGGCCGCAACCGAAATCGAGATGCGTCATC
TGGCTTTCAAGAAGCCGGGCGACGGGATCTCTGCGGCAAAGTACAAGGACGTGATCGGGCGACGCATCGTTCGGGCGTTG
CCGCGCGACCACAAGTTCGCATACGAGGACTTCGAATGA

Upstream 100 bases:

>100_bases
GCGCGTTCCGGGACCGCCGCCCGCCCTTGATTGAATCTTCGCACTCCGGTATGCCCACATCGGGCTCCAAGGAGTACATC
CGCCTAGAAAGCTTGAAAGC

Downstream 100 bases:

>100_bases
CCAAACGGAAAATCTGCGTGGTCGTCGGGTCGCGTGCCAATTACAGTTCCATCAAATCGGCGATGCGTGCGATCCAGGAT
CATCCTGCGCTCGAACTGCA

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPATSNPYIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYFSAEPRTAYFKRTGFSPEQWR
ALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSGEVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGSA
LTLLQCTSKYPCPPEQVGLNAMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEPDEF
RRLCRELKETARIIASPVDKDDLSSLSDMKLIFEKSIVSATDLPAATEIEMRHLAFKKPGDGISAAKYKDVIGRRIVRAL
PRDHKFAYEDFE

Sequences:

>Translated_332_residues
MPATSNPYIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYFSAEPRTAYFKRTGFSPEQWR
ALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSGEVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGSA
LTLLQCTSKYPCPPEQVGLNAMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEPDEF
RRLCRELKETARIIASPVDKDDLSSLSDMKLIFEKSIVSATDLPAATEIEMRHLAFKKPGDGISAAKYKDVIGRRIVRAL
PRDHKFAYEDFE
>Mature_331_residues
PATSNPYIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYFSAEPRTAYFKRTGFSPEQWRA
LAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSGEVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGSAL
TLLQCTSKYPCPPEQVGLNAMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEPDEFR
RLCRELKETARIIASPVDKDDLSSLSDMKLIFEKSIVSATDLPAATEIEMRHLAFKKPGDGISAAKYKDVIGRRIVRALP
RDHKFAYEDFE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=325, Percent_Identity=32.3076923076923, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21357081, Length=351, Percent_Identity=29.3447293447293, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36067; Mature: 35936

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATSNPYIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYF
CCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCC
SAEPRTAYFKRTGFSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSGE
CCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCEEEECCCCC
VSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGSALTLLQCTSKYPCPPEQVGLN
CCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCC
AMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEPDEF
HHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RRLCRELKETARIIASPVDKDDLSSLSDMKLIFEKSIVSATDLPAATEIEMRHLAFKKPG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
DGISAAKYKDVIGRRIVRALPRDHKFAYEDFE
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PATSNPYIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYF
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCC
SAEPRTAYFKRTGFSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSGE
CCCCCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCEEEECCCCC
VSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRGSALTLLQCTSKYPCPPEQVGLN
CCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCC
AMCVMRERYGIPVGYSDHTLGFAAPIAAVALGATVIEKHFTFSKLMYGSDAKNSMEPDEF
HHEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
RRLCRELKETARIIASPVDKDDLSSLSDMKLIFEKSIVSATDLPAATEIEMRHLAFKKPG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
DGISAAKYKDVIGRRIVRALPRDHKFAYEDFE
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]