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The map label for this gene is msrB [H]

Identifier: 86748643

GI number: 86748643

Start: 1712469

End: 1712882

Strand: Direct

Name: msrB [H]

Synonym: RPB_1518

Alternate gene names: 86748643

Gene position: 1712469-1712882 (Clockwise)

Preceding gene: 86748642

Following gene: 86748644

Centisome position: 32.12

GC content: 65.46

Gene sequence:

>414_bases
ATGACCGATACCAAGACGATACCCGGCAAGGTCGCCAAGAGCGAGGCCGAGTGGCGCAAGGAACTGACCCCGATGCAATA
CGCCGTGCTGCGCGAGAAGGCGACTGAGCGCCCGTTCTCGGGCGAATATGAGTACGAGACCACGCCGGGCACCTATGTCT
GCGCCGGCTGCGGCCAGACCCTGTTCGAGTCCGATGCGAAGTTCGATTCCGGTTGCGGCTGGCCGAGCTTCACCGCGCCG
GCGTCCGACGGCCACATCGACGAAGAGCGCGACGTCAGCCACGGCATGATCCGGACCGAGGTGCTGTGCGCGCGCTGCAA
TGGGCATCTCGGCCACGTGTTTCCCGATGGTCCGGGGCCGACGGGACTGCGCTATTGCATCAATTCGGCGGCGCTGAAGC
TGAAGCCGCGGTAG

Upstream 100 bases:

>100_bases
GAAGAAGCTGTTCCCGAAGGACTATCTCACCAAGCCGACGCTGGTGAGCAGCGCCAGGGCCACGAACTAGCGGCGATCGC
CCACACGTTCAGGAGTTGCC

Downstream 100 bases:

>100_bases
GCTCGCCCTGGGTCAGGGCCCCCAGCCGGGCGGGTCGCAATTGCTGAGATCGGGCGTATCATCCCTCCAGAGCCGGAGCG
GCGCTTGCGCGCCGCGTGCC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MTDTKTIPGKVAKSEAEWRKELTPMQYAVLREKATERPFSGEYEYETTPGTYVCAGCGQTLFESDAKFDSGCGWPSFTAP
ASDGHIDEERDVSHGMIRTEVLCARCNGHLGHVFPDGPGPTGLRYCINSAALKLKPR

Sequences:

>Translated_137_residues
MTDTKTIPGKVAKSEAEWRKELTPMQYAVLREKATERPFSGEYEYETTPGTYVCAGCGQTLFESDAKFDSGCGWPSFTAP
ASDGHIDEERDVSHGMIRTEVLCARCNGHLGHVFPDGPGPTGLRYCINSAALKLKPR
>Mature_136_residues
TDTKTIPGKVAKSEAEWRKELTPMQYAVLREKATERPFSGEYEYETTPGTYVCAGCGQTLFESDAKFDSGCGWPSFTAPA
SDGHIDEERDVSHGMIRTEVLCARCNGHLGHVFPDGPGPTGLRYCINSAALKLKPR

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=54.3307086614173, Blast_Score=143, Evalue=4e-35,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=54.3307086614173, Blast_Score=143, Evalue=4e-35,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=54.3307086614173, Blast_Score=143, Evalue=4e-35,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=54.3307086614173, Blast_Score=142, Evalue=6e-35,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=52.6717557251908, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=50.4132231404959, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17553450, Length=125, Percent_Identity=48, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=144, Percent_Identity=45.1388888888889, Blast_Score=116, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=129, Percent_Identity=48.062015503876, Blast_Score=122, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=53.1746031746032, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=53.1746031746032, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=53.1746031746032, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI221378664, Length=126, Percent_Identity=50.7936507936508, Blast_Score=136, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=48.9051094890511, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=48.9051094890511, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI221378662, Length=133, Percent_Identity=48.1203007518797, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15032; Mature: 14901

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTKTIPGKVAKSEAEWRKELTPMQYAVLREKATERPFSGEYEYETTPGTYVCAGCGQT
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEECCCCCEEECCCCCH
LFESDAKFDSGCGWPSFTAPASDGHIDEERDVSHGMIRTEVLCARCNGHLGHVFPDGPGP
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
TGLRYCINSAALKLKPR
HHHHHHHCCCCEEECCC
>Mature Secondary Structure 
TDTKTIPGKVAKSEAEWRKELTPMQYAVLREKATERPFSGEYEYETTPGTYVCAGCGQT
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEECCCCCEEECCCCCH
LFESDAKFDSGCGWPSFTAPASDGHIDEERDVSHGMIRTEVLCARCNGHLGHVFPDGPGP
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
TGLRYCINSAALKLKPR
HHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]