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The map label for this gene is lpsI [H]

Identifier: 86748583

GI number: 86748583

Start: 1647986

End: 1648702

Strand: Direct

Name: lpsI [H]

Synonym: RPB_1458

Alternate gene names: 86748583

Gene position: 1647986-1648702 (Clockwise)

Preceding gene: 86748581

Following gene: 86748584

Centisome position: 30.91

GC content: 64.44

Gene sequence:

>717_bases
ATGAACAAGGTATATCCCGACGCCCAATCGGCTCTCGCCGGAATCCTGCGGGACGGCATGATGATCATGTCCGGCGGTTT
CGGGCTGTGCGGTATCGCCGAAACGTTGTCGGATGCGCTGCGCGACTCCGGCGTCAAGGACCTCACGGTGGTCTCGAACA
ATGCCGGTGTCGACGGCATCGGCCTCTCCAGGCTGCTGGAGACCCGGCAGATCAAGAAGATGATCTCGTCCTATGTGGGC
GAAAACAAGCTGTTCGCGCAGCAGTTCCTGGCCGGCGAGCTCGAGCTCGAATTCGCCCCGCAGGGCACGCTGGCCGAGCG
CATCCGCGCCGGCGGCGCCGGCATCCCGGCGTTCTTCACCAAGACCGGCGTCGGCACGCTGGTGGCCGAAGGCAAGGAAA
TCCGCGAATTCGACGGCGAGAAATACGTCATGGAGCGCGGCCTGTTCGCCGATCTCGCCATCGTCCACGCCTGGAAGGGC
GATACCGCCGGCAATCTCGTGTACCGCAAGACCGCGCGCAACTTCAATCCGATGATGGCGACCGCGGCCAAGATCACCAT
CGCCGAGGTCGAGCATCTGGTGCCGGCCGGCGAGATCGATCCCGATCACATCCACACGCCCGGCATCTTCGTCCAGCGCA
TCATCGAAGTCGGCTCCGCCAAGAAGCACATCGAGCAGCGCACCACCCGCAAGCGCCCCGAAGCCGCGGCAACCTGA

Upstream 100 bases:

>100_bases
GCCTTCCGGGCCGCAGCGTGTCGGCGCAATTGACGGCCAGCGCCGATTTTGCTGAATAGACCCACTCGCAGAACAGCCCC
TCTCATCAGGTCCCTGCATC

Downstream 100 bases:

>100_bases
GGAGAGTTCTGATGGCCTGGACCCGCGAACAGATGGCAGCGCGCGCCGCCAAGGAATTGCGCGACGGTTTCTACGTCAAT
CTCGGTATCGGGATTCCGAC

Product: 3-oxoacid CoA-transferase, subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MNKVYPDAQSALAGILRDGMMIMSGGFGLCGIAETLSDALRDSGVKDLTVVSNNAGVDGIGLSRLLETRQIKKMISSYVG
ENKLFAQQFLAGELELEFAPQGTLAERIRAGGAGIPAFFTKTGVGTLVAEGKEIREFDGEKYVMERGLFADLAIVHAWKG
DTAGNLVYRKTARNFNPMMATAAKITIAEVEHLVPAGEIDPDHIHTPGIFVQRIIEVGSAKKHIEQRTTRKRPEAAAT

Sequences:

>Translated_238_residues
MNKVYPDAQSALAGILRDGMMIMSGGFGLCGIAETLSDALRDSGVKDLTVVSNNAGVDGIGLSRLLETRQIKKMISSYVG
ENKLFAQQFLAGELELEFAPQGTLAERIRAGGAGIPAFFTKTGVGTLVAEGKEIREFDGEKYVMERGLFADLAIVHAWKG
DTAGNLVYRKTARNFNPMMATAAKITIAEVEHLVPAGEIDPDHIHTPGIFVQRIIEVGSAKKHIEQRTTRKRPEAAAT
>Mature_238_residues
MNKVYPDAQSALAGILRDGMMIMSGGFGLCGIAETLSDALRDSGVKDLTVVSNNAGVDGIGLSRLLETRQIKKMISSYVG
ENKLFAQQFLAGELELEFAPQGTLAERIRAGGAGIPAFFTKTGVGTLVAEGKEIREFDGEKYVMERGLFADLAIVHAWKG
DTAGNLVYRKTARNFNPMMATAAKITIAEVEHLVPAGEIDPDHIHTPGIFVQRIIEVGSAKKHIEQRTTRKRPEAAAT

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=253, Percent_Identity=50.9881422924901, Blast_Score=253, Evalue=1e-67,
Organism=Homo sapiens, GI11545841, Length=253, Percent_Identity=49.4071146245059, Blast_Score=230, Evalue=1e-60,
Organism=Escherichia coli, GI1788551, Length=203, Percent_Identity=46.3054187192118, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=51.2295081967213, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=50.8264462809917, Blast_Score=244, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24655794, Length=249, Percent_Identity=50.2008032128514, Blast_Score=243, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25659; Mature: 25659

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYPDAQSALAGILRDGMMIMSGGFGLCGIAETLSDALRDSGVKDLTVVSNNAGVDGI
CCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
GLSRLLETRQIKKMISSYVGENKLFAQQFLAGELELEFAPQGTLAERIRAGGAGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKEIREFDGEKYVMERGLFADLAIVHAWKGDTAGNLVYRKTARNFNPMMA
HCCCHHHHHCCHHHHHHCCHHHHHHCCCHHHHHHHEECCCCCCCCEEEEHHHCCCCHHHH
TAAKITIAEVEHLVPAGEIDPDHIHTPGIFVQRIIEVGSAKKHIEQRTTRKRPEAAAT
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNKVYPDAQSALAGILRDGMMIMSGGFGLCGIAETLSDALRDSGVKDLTVVSNNAGVDGI
CCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCH
GLSRLLETRQIKKMISSYVGENKLFAQQFLAGELELEFAPQGTLAERIRAGGAGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTLVAEGKEIREFDGEKYVMERGLFADLAIVHAWKGDTAGNLVYRKTARNFNPMMA
HCCCHHHHHCCHHHHHHCCHHHHHHCCCHHHHHHHEECCCCCCCCEEEEHHHCCCCHHHH
TAAKITIAEVEHLVPAGEIDPDHIHTPGIFVQRIIEVGSAKKHIEQRTTRKRPEAAAT
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]