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The map label for this gene is exbB [H]

Identifier: 86748366

GI number: 86748366

Start: 1420512

End: 1421312

Strand: Direct

Name: exbB [H]

Synonym: RPB_1241

Alternate gene names: 86748366

Gene position: 1420512-1421312 (Clockwise)

Preceding gene: 86748362

Following gene: 86748367

Centisome position: 26.64

GC content: 71.41

Gene sequence:

>801_bases
ATGCCGCTGATTTCGATGGTCTCGACGTTCAGGAATGCTGCTGCCGCGGGCGTGCTGGCCGCCGCGGCATCGCTGCTGCC
GTGCAGTCCCGGCGTCGCCGCCACCGACGTCGCGTCGTTGCCGCGCGACCTGTCGCCCTGGGGCATGTTCACGAGCGCCG
ACATCGTCGTGCAGGTGGTGATGGCCGGCCTCGTGGTCGCGTCGCTCGCGACCTGGACGGTGTGGCTGTCGAAGACGCTC
GAGCTGCGCCGCGAGACCGCGCGCGCCCGGGACGGATTGGCCAGGCTCGAAGCGGACGTCACGCTGGCCGAACTGCGCAG
CGCCGACGAGGCGCAGGACGCGGTGGCGCAATTGGTGCAGACCGCGGCGCGCGAAGCCAGCCTGTCCGGCTGGAGCTTCG
ACGACGAGTTCAAGGAGCGCGTCGCGCTGCGGCTGGAGCGGGTCGAGGCGGCGATGTCGCGGCGGATCGCGCGCGGCACC
GGCATTCTGGCGACCATCGGCGCGGTGGCGCCGTTCGTCGGCCTGTTCGGCACGGTGTGGGGCATCATGAATGCGTTCAT
CGGGATTTCCGAAGCGCACACCACCAATTTGGCGGTGGTCGCGCCGGGCATTGCCGAGGCGCTGCTCGCCACCGCGCTCG
GCCTCGTCGCCGCGGTGCCGGCGGTGGTGATCTACAACTATCTGGTCCGCGGGATCGCCAATTATCGCGCGCTGCTCGGC
GACGCCTCGGCGCAGGTGCTGCTGCTGGTCAGCCGCGACCGCGGCCGCTCGGCGCGGCTGATGGCGCGAGCCGCGGAGTA
G

Upstream 100 bases:

>100_bases
GGACCTGGGCGAAACCCGGCTGGAATTGATTTTTCGGGCGTGGCGTTCCGTGCGATAGGTCGAGCCCTTCCGCGTCTTCC
TCAGCCGCTGAAAGTGGATC

Downstream 100 bases:

>100_bases
GCGATGGGCGTGCGACTCGGGGCGAGGCGGCGGCAGGGCGCCGAGGACGATCTCGCCGTCGCGCACGAGATCAACGTCAC
GCCGTTCATCGACGTGATGC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPLISMVSTFRNAAAAGVLAAAASLLPCSPGVAATDVASLPRDLSPWGMFTSADIVVQVVMAGLVVASLATWTVWLSKTL
ELRRETARARDGLARLEADVTLAELRSADEAQDAVAQLVQTAAREASLSGWSFDDEFKERVALRLERVEAAMSRRIARGT
GILATIGAVAPFVGLFGTVWGIMNAFIGISEAHTTNLAVVAPGIAEALLATALGLVAAVPAVVIYNYLVRGIANYRALLG
DASAQVLLLVSRDRGRSARLMARAAE

Sequences:

>Translated_266_residues
MPLISMVSTFRNAAAAGVLAAAASLLPCSPGVAATDVASLPRDLSPWGMFTSADIVVQVVMAGLVVASLATWTVWLSKTL
ELRRETARARDGLARLEADVTLAELRSADEAQDAVAQLVQTAAREASLSGWSFDDEFKERVALRLERVEAAMSRRIARGT
GILATIGAVAPFVGLFGTVWGIMNAFIGISEAHTTNLAVVAPGIAEALLATALGLVAAVPAVVIYNYLVRGIANYRALLG
DASAQVLLLVSRDRGRSARLMARAAE
>Mature_265_residues
PLISMVSTFRNAAAAGVLAAAASLLPCSPGVAATDVASLPRDLSPWGMFTSADIVVQVVMAGLVVASLATWTVWLSKTLE
LRRETARARDGLARLEADVTLAELRSADEAQDAVAQLVQTAAREASLSGWSFDDEFKERVALRLERVEAAMSRRIARGTG
ILATIGAVAPFVGLFGTVWGIMNAFIGISEAHTTNLAVVAPGIAEALLATALGLVAAVPAVVIYNYLVRGIANYRALLGD
ASAQVLLLVSRDRGRSARLMARAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=224, Percent_Identity=54.4642857142857, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1786958, Length=225, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 27886; Mature: 27754

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLISMVSTFRNAAAAGVLAAAASLLPCSPGVAATDVASLPRDLSPWGMFTSADIVVQVV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHH
MAGLVVASLATWTVWLSKTLELRRETARARDGLARLEADVTLAELRSADEAQDAVAQLVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TAAREASLSGWSFDDEFKERVALRLERVEAAMSRRIARGTGILATIGAVAPFVGLFGTVW
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIMNAFIGISEAHTTNLAVVAPGIAEALLATALGLVAAVPAVVIYNYLVRGIANYRALLG
HHHHHHHCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DASAQVLLLVSRDRGRSARLMARAAE
CCCCEEEEEEECCCCCHHHHHHHCCC
>Mature Secondary Structure 
PLISMVSTFRNAAAAGVLAAAASLLPCSPGVAATDVASLPRDLSPWGMFTSADIVVQVV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHH
MAGLVVASLATWTVWLSKTLELRRETARARDGLARLEADVTLAELRSADEAQDAVAQLVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TAAREASLSGWSFDDEFKERVALRLERVEAAMSRRIARGTGILATIGAVAPFVGLFGTVW
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIMNAFIGISEAHTTNLAVVAPGIAEALLATALGLVAAVPAVVIYNYLVRGIANYRALLG
HHHHHHHCCCHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DASAQVLLLVSRDRGRSARLMARAAE
CCCCEEEEEEECCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]