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The map label for this gene is fbcH [H]

Identifier: 86748326

GI number: 86748326

Start: 1374860

End: 1376929

Strand: Direct

Name: fbcH [H]

Synonym: RPB_1201

Alternate gene names: 86748326

Gene position: 1374860-1376929 (Clockwise)

Preceding gene: 86748325

Following gene: 86748327

Centisome position: 25.79

GC content: 63.19

Gene sequence:

>2070_bases
ATGAGCGGACCATCGACCTATCAGCCGCAGAGCCCCTTCATGAAGTGGCTCGAGCAACGCCTGCCGATCGCCGGGCTGGT
TCATTCGTCGTTCATTGCCTACCCCACGCCGCGCAACCTGAACTACTGGTGGACGTTCGGCGCCATTCTCTCGATGATGC
TGGCGGTGCAGATCATCACCGGCATCGTGCTGGCGATGCACTACACGCCGCACGTCGACTTCGCCTTCGACTCGGTCGAG
CGGATCGTTCGCGACGTCAACTACGGCTGGCTGCTGCGCAACACCCACGCGGCCGGCGCGTCGATGTTCTTCATCGCGGT
CTACATCCACATGTTCCGCGGCCTGTATTACGGGTCGTACAAGGCGCCGCGTGAAGTGCTCTGGATCCTCGGCGTGATCA
TCTACCTGCTTATGATGGCGACCGGCTTCATGGGCTATGTGCTTCCCTGGGGCCAGATGAGCTTCTGGGGCGCCACCGTG
ATCACCAACCTGTTCTCGGCGGTCCCGTTCGTCGGCGACAGCATCGTGACCTTGCTGTGGGGCGGCTATTCGGTCGGCAA
CCCGACCCTGAACCGGTTCTTCTCGCTGCACTATCTGCTGCCCTTCGTGATTGCCGGCGTGGTCGTGCTGCACGTCTGGG
CGTTGCACGTCACCGGTCAGAACAACCCGACCGGCGTCGAGCCGAAGACCGAGAAGGACACGGTCGCGTTCACGCCCTAC
GCGACGATGAAGGACGTGTTCGGCATGTCCTGCTTCCTGCTGTTCTTTTCCTGGTTCATTTTCTACATGCCGAACTATCT
CGGTGAGGCCGACAACTACATTCCGGCGAATCCGGGCGTGACGCCGCCGCATATCGTTCCGGAATGGTACTACCTGCCGT
TCTACGCGATCCTGCGGTCGATCCCGAACAAGCTGATGGGCGTCGTGGCGATGTTCGGCGCCATCATCGTGCTGCTGTTC
CTGCCCTGGCTCGACAGCGCCAAGGTGCGCTCGTCGCGCTACCGGCCGCTGGCGAAGCGGTTCTTCTGGGGCTTCGTGGT
GGTCTGCATCATGCTCGGATGGCTCGGCTCGAAGCCGGCGGAGGGCATCTACACGGTCCTCGCCCGCGTCTTCACCTTCG
CCTATTTCGCCTACTTCCTGATCGTGTTGCCGCTACTGTCCAGGGTCGAGAAGACGCTGCCGCTGCCGAACTCGATCTCG
GAGGACGTGCTGAGCAAGGGCAAGACGGCGGGAGCAACCGCGGCGAGCCTGCTCGCCCTGGTGATGGCCGGGACGCTGAT
GTTCGGCGGGGTGCAGAGCGCCAAGGCGGCGGAAGGCGGCGAGAGTCCGCCGTCGCTGGAGTGGAGCTTTGCCGGCCCGT
TCGGCACCTACGATCGCCCCCAATTGCAGCGCGGCTTCAAGATCTACAAGGAGGTGTGCTCCGCCTGTCACTCGCTGAAG
TTGCTGCAGTATCGCAACCTCGCCGAGCCGGGTGGACCGGGCTTCACGATCGAACAGGCCAAGGCGATCGCCGCCGAAGC
CTCGATCAAGGACGGCCCGAACGACGCCGGCGAAATGTTCGAACGCCCCGGCCGGCTCGCCGACACCTTCCATTCGCCGT
TCCCGAACGAGCAGGCGGCGCGCTCGGCCAATGGCGGTGCGGTTCCGCCGGACATGTCGCTGCTCGCCAAGGCGCGTTCC
TATCCGCGTGGCTTCCCGCAGTTCGTGTTCGACTTCTTCACCCAGTTCCAGGAGCAGGGCCCGAACTACATCGATGCGCT
GCTTCAGGGTTATCAGGACACGCCGCCGGAGGGCTTCACGCTGCCGGACGGGGCTTACTACAACAAGTGGTATCCGGGCC
ATTCGATCAAAATGCCGCCGCCGATTTCGGACGGTCAGGTGAGCTTCGACGACGGCAGCCCGGAGACCGTGCCGCAATAT
GCCAAGGACGTCACGGCTTTCCTGATGTGGGCTGCCGAGCCGCATCTCGAAGCCCGCAAGCGCCTCGGTCTGCAGGTCAT
GATCTTCCTGATCATCCTCAGCGGCCTGCTGTACTTCACCAAGCGCAAGATCTGGTCGAACGTGCACTGA

Upstream 100 bases:

>100_bases
CCTGCCGGTTCCGCCCTACCAATTCGTCTCCGACACCAAAATCCAGATCGGCTGACGCCTCCCGACCAGCGTCGCTATAT
CCCTTGCTTAGGATCGCATC

Downstream 100 bases:

>100_bases
ACTCGGTCGACGAGAGTGCAGACGACGAACGCGTGACAGAAAGCCCCTTCGGGGGCTTTTTTGTTATGCGGAGTCCGCGA
TCTGCCGTGGCGACTCCGGC

Product: cytochrome c1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MSGPSTYQPQSPFMKWLEQRLPIAGLVHSSFIAYPTPRNLNYWWTFGAILSMMLAVQIITGIVLAMHYTPHVDFAFDSVE
RIVRDVNYGWLLRNTHAAGASMFFIAVYIHMFRGLYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAVPFVGDSIVTLLWGGYSVGNPTLNRFFSLHYLLPFVIAGVVVLHVWALHVTGQNNPTGVEPKTEKDTVAFTPY
ATMKDVFGMSCFLLFFSWFIFYMPNYLGEADNYIPANPGVTPPHIVPEWYYLPFYAILRSIPNKLMGVVAMFGAIIVLLF
LPWLDSAKVRSSRYRPLAKRFFWGFVVVCIMLGWLGSKPAEGIYTVLARVFTFAYFAYFLIVLPLLSRVEKTLPLPNSIS
EDVLSKGKTAGATAASLLALVMAGTLMFGGVQSAKAAEGGESPPSLEWSFAGPFGTYDRPQLQRGFKIYKEVCSACHSLK
LLQYRNLAEPGGPGFTIEQAKAIAAEASIKDGPNDAGEMFERPGRLADTFHSPFPNEQAARSANGGAVPPDMSLLAKARS
YPRGFPQFVFDFFTQFQEQGPNYIDALLQGYQDTPPEGFTLPDGAYYNKWYPGHSIKMPPPISDGQVSFDDGSPETVPQY
AKDVTAFLMWAAEPHLEARKRLGLQVMIFLIILSGLLYFTKRKIWSNVH

Sequences:

>Translated_689_residues
MSGPSTYQPQSPFMKWLEQRLPIAGLVHSSFIAYPTPRNLNYWWTFGAILSMMLAVQIITGIVLAMHYTPHVDFAFDSVE
RIVRDVNYGWLLRNTHAAGASMFFIAVYIHMFRGLYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAVPFVGDSIVTLLWGGYSVGNPTLNRFFSLHYLLPFVIAGVVVLHVWALHVTGQNNPTGVEPKTEKDTVAFTPY
ATMKDVFGMSCFLLFFSWFIFYMPNYLGEADNYIPANPGVTPPHIVPEWYYLPFYAILRSIPNKLMGVVAMFGAIIVLLF
LPWLDSAKVRSSRYRPLAKRFFWGFVVVCIMLGWLGSKPAEGIYTVLARVFTFAYFAYFLIVLPLLSRVEKTLPLPNSIS
EDVLSKGKTAGATAASLLALVMAGTLMFGGVQSAKAAEGGESPPSLEWSFAGPFGTYDRPQLQRGFKIYKEVCSACHSLK
LLQYRNLAEPGGPGFTIEQAKAIAAEASIKDGPNDAGEMFERPGRLADTFHSPFPNEQAARSANGGAVPPDMSLLAKARS
YPRGFPQFVFDFFTQFQEQGPNYIDALLQGYQDTPPEGFTLPDGAYYNKWYPGHSIKMPPPISDGQVSFDDGSPETVPQY
AKDVTAFLMWAAEPHLEARKRLGLQVMIFLIILSGLLYFTKRKIWSNVH
>Mature_688_residues
SGPSTYQPQSPFMKWLEQRLPIAGLVHSSFIAYPTPRNLNYWWTFGAILSMMLAVQIITGIVLAMHYTPHVDFAFDSVER
IVRDVNYGWLLRNTHAAGASMFFIAVYIHMFRGLYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATVI
TNLFSAVPFVGDSIVTLLWGGYSVGNPTLNRFFSLHYLLPFVIAGVVVLHVWALHVTGQNNPTGVEPKTEKDTVAFTPYA
TMKDVFGMSCFLLFFSWFIFYMPNYLGEADNYIPANPGVTPPHIVPEWYYLPFYAILRSIPNKLMGVVAMFGAIIVLLFL
PWLDSAKVRSSRYRPLAKRFFWGFVVVCIMLGWLGSKPAEGIYTVLARVFTFAYFAYFLIVLPLLSRVEKTLPLPNSISE
DVLSKGKTAGATAASLLALVMAGTLMFGGVQSAKAAEGGESPPSLEWSFAGPFGTYDRPQLQRGFKIYKEVCSACHSLKL
LQYRNLAEPGGPGFTIEQAKAIAAEASIKDGPNDAGEMFERPGRLADTFHSPFPNEQAARSANGGAVPPDMSLLAKARSY
PRGFPQFVFDFFTQFQEQGPNYIDALLQGYQDTPPEGFTLPDGAYYNKWYPGHSIKMPPPISDGQVSFDDGSPETVPQYA
KDVTAFLMWAAEPHLEARKRLGLQVMIFLIILSGLLYFTKRKIWSNVH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=377, Percent_Identity=48.0106100795756, Blast_Score=355, Evalue=8e-98,
Organism=Homo sapiens, GI21359867, Length=244, Percent_Identity=43.4426229508197, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17506225, Length=278, Percent_Identity=36.3309352517986, Blast_Score=151, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6226529, Length=368, Percent_Identity=52.9891304347826, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226532, Length=245, Percent_Identity=52.2448979591837, Blast_Score=266, Evalue=7e-72,
Organism=Saccharomyces cerevisiae, GI6324639, Length=294, Percent_Identity=41.156462585034, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6226531, Length=164, Percent_Identity=55.4878048780488, Blast_Score=191, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6226530, Length=155, Percent_Identity=47.741935483871, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24658292, Length=265, Percent_Identity=39.622641509434, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI21358225, Length=267, Percent_Identity=39.3258426966292, Blast_Score=189, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 76946; Mature: 76815

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS51007 CYTC ; PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGPSTYQPQSPFMKWLEQRLPIAGLVHSSFIAYPTPRNLNYWWTFGAILSMMLAVQIIT
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHH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HCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]