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The map label for this gene is moaE [H]

Identifier: 86748299

GI number: 86748299

Start: 1348237

End: 1348704

Strand: Reverse

Name: moaE [H]

Synonym: RPB_1174

Alternate gene names: 86748299

Gene position: 1348704-1348237 (Counterclockwise)

Preceding gene: 86748300

Following gene: 86748298

Centisome position: 25.3

GC content: 67.09

Gene sequence:

>468_bases
ATGACCGTTCCGGTGACGATCCGCATTCAGGACGCCGATTTCGACATCGCCGCAGAGATCGCGGCTATGTCGAAAGGGCG
CACCGATATCGGCGCGGTGGTGAGTTTCAGCGGCATCTGCCGCGGCGCCGAAGGCGATGATGCGGTCGCAGCACTGACGC
TCGAGCATTATCCCGGCATGGCGGAAGACGAGATCGGCCGCCACGCCGCCGAAGCCGTGAAGCGCTGGCCGGTGACCGCA
CTGACCATAGTCCACCGCGTCGGCCGGATGCTGCCGGGCGACAACATCGTGCTGGTGCTGGCCGCGTCGTCGCACCGGCA
AGCCGCATTCGCAGCGGCCGAATTCCTGATGGATTATCTGAAGGCCAACGCGCCGTTCTGGAAGCGCGAGGAGCGCGCCG
ACGGCACGCGCTGGGTCGAGGCGCACGACCGCGACGACGCGGCCGCCGCGCGATGGAGCAAGGATTGA

Upstream 100 bases:

>100_bases
CACCCATGTGCGCCCCGACACGCCGATCGCTGGCGCCCGCGAGGTCGCCTTTTTCCCGCCGATGACCGGCGGCTGAGCGC
GCCGCGCACGGGATGATCCG

Downstream 100 bases:

>100_bases
TGGCGAAACAAGCGAAGGCGAAAGCCGCGAAGAAGAAGACGCCGGCGAAGCGGCCTGCCAAGCCCCGCGCCGCGGCAAAA
GTCACCCCGGCCTCCGGGCA

Product: molybdopterin biosynthesis MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTVPVTIRIQDADFDIAAEIAAMSKGRTDIGAVVSFSGICRGAEGDDAVAALTLEHYPGMAEDEIGRHAAEAVKRWPVTA
LTIVHRVGRMLPGDNIVLVLAASSHRQAAFAAAEFLMDYLKANAPFWKREERADGTRWVEAHDRDDAAAARWSKD

Sequences:

>Translated_155_residues
MTVPVTIRIQDADFDIAAEIAAMSKGRTDIGAVVSFSGICRGAEGDDAVAALTLEHYPGMAEDEIGRHAAEAVKRWPVTA
LTIVHRVGRMLPGDNIVLVLAASSHRQAAFAAAEFLMDYLKANAPFWKREERADGTRWVEAHDRDDAAAARWSKD
>Mature_154_residues
TVPVTIRIQDADFDIAAEIAAMSKGRTDIGAVVSFSGICRGAEGDDAVAALTLEHYPGMAEDEIGRHAAEAVKRWPVTAL
TIVHRVGRMLPGDNIVLVLAASSHRQAAFAAAEFLMDYLKANAPFWKREERADGTRWVEAHDRDDAAAARWSKD

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=108, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787003, Length=146, Percent_Identity=47.2602739726027, Blast_Score=142, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16860; Mature: 16729

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPVTIRIQDADFDIAAEIAAMSKGRTDIGAVVSFSGICRGAEGDDAVAALTLEHYPGM
CCCEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCC
AEDEIGRHAAEAVKRWPVTALTIVHRVGRMLPGDNIVLVLAASSHRQAAFAAAEFLMDYL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
KANAPFWKREERADGTRWVEAHDRDDAAAARWSKD
HCCCCCCCCHHCCCCCEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure 
TVPVTIRIQDADFDIAAEIAAMSKGRTDIGAVVSFSGICRGAEGDDAVAALTLEHYPGM
CCEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEHHHCCCC
AEDEIGRHAAEAVKRWPVTALTIVHRVGRMLPGDNIVLVLAASSHRQAAFAAAEFLMDYL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
KANAPFWKREERADGTRWVEAHDRDDAAAARWSKD
HCCCCCCCCHHCCCCCEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]