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The map label for this gene is yfcB [H]

Identifier: 86748298

GI number: 86748298

Start: 1347173

End: 1348237

Strand: Reverse

Name: yfcB [H]

Synonym: RPB_1173

Alternate gene names: 86748298

Gene position: 1348237-1347173 (Counterclockwise)

Preceding gene: 86748299

Following gene: 86748295

Centisome position: 25.29

GC content: 65.73

Gene sequence:

>1065_bases
ATGGCGAAACAAGCGAAGGCGAAAGCCGCGAAGAAGAAGACGCCGGCGAAGCGGCCTGCCAAGCCCCGCGCCGCGGCAAA
AGTCACCCCGGCCTCCGGGCACGAGCGACCGGCGAAGCGCCGCGTCGCCGTGGCGATGCCGCTGGATCTCGAACTCGATC
CCTACGAAATGTTTCCGGGCGAACTGGTCAGCCTGCTCGACTTCGTCCGCTTCGCCGTGAGCCGCTTCGCCGAGGCCGGC
GTGGTGTTCGCACACGGTACCACCGATCCGATCGCCGAAGCCGTGTTCCTGATCGGCGAAGCGCTGCATCTGCATCCCGA
CCAGTTCGAGATGTTCGCGACCGCACGCGTCACCGATCACGAGGCCGTTGGGATTCTCCATCTCATCGAGCAACGCATCA
CGACGCGGCTGCCCGCCGCCTATCTCGTCAACAAGATCTACATGCGCGGCGTGCCGTTCTACGTCGACGAACGCGTGATC
GTGCCGCGCTCCTATATCGGCGAACTGCTCGACTCGCATTTCGACGGCGGCGAGACCTCGCTGATCGGCGATCCGGAAGC
AGTCGCGCGCGTGCTCGATCTGTGCACTGGCTCGGGTTGCCTCGCAATTCTCGCGGCGCGCAGCTTTCCCAATGCGGCCG
TCGACGCCGTCGATCTGTCGGAGGATGCGCTCGCGGTCGCAACCCGCAACGTCGCCGACCACCATCTTGGGGATCGCCTC
TCGCTGCATCACGGCGACCTGTTCGCGCCGCTGCTGCAGGATGCCCGCTACGATCTGATCATCACCAACCCGCCTTACGT
CGACGCCGACGGCATGGCGAATCTGCCGGCCGAATGCCGCGCCGAACCGGCGATGGCGTTCGACGGCGGCGACGATGGAC
TCGATATCATCCGCCGGATTCTGGCCGAGGCGAAGGATCATCTCACGCCGGACGGCGGCCTGCTGTGCGAAGTCGGCCGC
TGCCGCCCCGCGATCGAACAGGACTTCCCGCATCTGCCGCTGCTGTGGCTCGACAGCGAGGATTCCGAAGGCGAAGTGTT
CTGGATCGCCGCGGCGGATTTGTAG

Upstream 100 bases:

>100_bases
ACGCGCCGTTCTGGAAGCGCGAGGAGCGCGCCGACGGCACGCGCTGGGTCGAGGCGCACGACCGCGACGACGCGGCCGCC
GCGCGATGGAGCAAGGATTG

Downstream 100 bases:

>100_bases
ACGATTAGAGCAGCTCTGGTTTTGATGGAATCACCGCCGTCATCCTGAGGTGCCCGCTGGGCCGCGCATGCGCGGCGCTG
CGGGCCTCGAAGGATGAGCC

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MAKQAKAKAAKKKTPAKRPAKPRAAAKVTPASGHERPAKRRVAVAMPLDLELDPYEMFPGELVSLLDFVRFAVSRFAEAG
VVFAHGTTDPIAEAVFLIGEALHLHPDQFEMFATARVTDHEAVGILHLIEQRITTRLPAAYLVNKIYMRGVPFYVDERVI
VPRSYIGELLDSHFDGGETSLIGDPEAVARVLDLCTGSGCLAILAARSFPNAAVDAVDLSEDALAVATRNVADHHLGDRL
SLHHGDLFAPLLQDARYDLIITNPPYVDADGMANLPAECRAEPAMAFDGGDDGLDIIRRILAEAKDHLTPDGGLLCEVGR
CRPAIEQDFPHLPLLWLDSEDSEGEVFWIAAADL

Sequences:

>Translated_354_residues
MAKQAKAKAAKKKTPAKRPAKPRAAAKVTPASGHERPAKRRVAVAMPLDLELDPYEMFPGELVSLLDFVRFAVSRFAEAG
VVFAHGTTDPIAEAVFLIGEALHLHPDQFEMFATARVTDHEAVGILHLIEQRITTRLPAAYLVNKIYMRGVPFYVDERVI
VPRSYIGELLDSHFDGGETSLIGDPEAVARVLDLCTGSGCLAILAARSFPNAAVDAVDLSEDALAVATRNVADHHLGDRL
SLHHGDLFAPLLQDARYDLIITNPPYVDADGMANLPAECRAEPAMAFDGGDDGLDIIRRILAEAKDHLTPDGGLLCEVGR
CRPAIEQDFPHLPLLWLDSEDSEGEVFWIAAADL
>Mature_353_residues
AKQAKAKAAKKKTPAKRPAKPRAAAKVTPASGHERPAKRRVAVAMPLDLELDPYEMFPGELVSLLDFVRFAVSRFAEAGV
VFAHGTTDPIAEAVFLIGEALHLHPDQFEMFATARVTDHEAVGILHLIEQRITTRLPAAYLVNKIYMRGVPFYVDERVIV
PRSYIGELLDSHFDGGETSLIGDPEAVARVLDLCTGSGCLAILAARSFPNAAVDAVDLSEDALAVATRNVADHHLGDRLS
LHHGDLFAPLLQDARYDLIITNPPYVDADGMANLPAECRAEPAMAFDGGDDGLDIIRRILAEAKDHLTPDGGLLCEVGRC
RPAIEQDFPHLPLLWLDSEDSEGEVFWIAAADL

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=264, Percent_Identity=26.8939393939394, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87082085, Length=295, Percent_Identity=44.7457627118644, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787463, Length=208, Percent_Identity=28.8461538461538, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24582226, Length=246, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 38463; Mature: 38332

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQAKAKAAKKKTPAKRPAKPRAAAKVTPASGHERPAKRRVAVAMPLDLELDPYEMFPG
CCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHCHH
ELVSLLDFVRFAVSRFAEAGVVFAHGTTDPIAEAVFLIGEALHLHPDQFEMFATARVTDH
HHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEECCCC
EAVGILHLIEQRITTRLPAAYLVNKIYMRGVPFYVDERVIVPRSYIGELLDSHFDGGETS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCEEECCHHHHHHHHHHCCCCCCCC
LIGDPEAVARVLDLCTGSGCLAILAARSFPNAAVDAVDLSEDALAVATRNVADHHLGDRL
CCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
SLHHGDLFAPLLQDARYDLIITNPPYVDADGMANLPAECRAEPAMAFDGGDDGLDIIRRI
EECCCCHHHHHHHCCCCCEEECCCCEECCCCCCCCCHHHCCCCCEEECCCCCCHHHHHHH
LAEAKDHLTPDGGLLCEVGRCRPAIEQDFPHLPLLWLDSEDSEGEVFWIAAADL
HHHHHHCCCCCCCEEEECCCCCCCHHHCCCCCCEEEECCCCCCCCEEEEEECCC
>Mature Secondary Structure 
AKQAKAKAAKKKTPAKRPAKPRAAAKVTPASGHERPAKRRVAVAMPLDLELDPYEMFPG
CCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHCHH
ELVSLLDFVRFAVSRFAEAGVVFAHGTTDPIAEAVFLIGEALHLHPDQFEMFATARVTDH
HHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEECCCC
EAVGILHLIEQRITTRLPAAYLVNKIYMRGVPFYVDERVIVPRSYIGELLDSHFDGGETS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCEEECCHHHHHHHHHHCCCCCCCC
LIGDPEAVARVLDLCTGSGCLAILAARSFPNAAVDAVDLSEDALAVATRNVADHHLGDRL
CCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
SLHHGDLFAPLLQDARYDLIITNPPYVDADGMANLPAECRAEPAMAFDGGDDGLDIIRRI
EECCCCHHHHHHHCCCCCEEECCCCEECCCCCCCCCHHHCCCCCEEECCCCCCHHHHHHH
LAEAKDHLTPDGGLLCEVGRCRPAIEQDFPHLPLLWLDSEDSEGEVFWIAAADL
HHHHHHCCCCCCCEEEECCCCCCCHHHCCCCCCEEEECCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2182772; 2969724; 7984428 [H]