Click here to switch to the map view.

The map label for this gene is yabF [C]

Identifier: 86747949

GI number: 86747949

Start: 938709

End: 939509

Strand: Direct

Name: yabF [C]

Synonym: RPB_0823

Alternate gene names: 86747949

Gene position: 938709-939509 (Clockwise)

Preceding gene: 86747947

Following gene: 86747950

Centisome position: 17.61

GC content: 67.17

Gene sequence:

>801_bases
ATGAAAGTTCTTCTGGTCTTCGCCCATCCCGAACCTCTTTCGCTGAATGGCGCTCTGCGCGACGCCGCGGTCGCGGAGCT
GCAGCGCCAGGGCCACGAGGTGCGGATCTCGGACCTCTATGCCCAGAACTGGAAGCCCGCGATCGACCGCGCCGATTTTC
CGAACCTCGCGCCTGACGAGCGCTTGCTGACGAGCGCGGCCTCCAAGGCGAGCTTCGACGCCGGAGAGCTGACGCAGGAT
GTCCGCGCCGAGATCGACAAGCTGCTCTGGGCGGATGTCCTGATCCTGCAATTCCCGCTGTGGTGGTTCAGTATGCCGGC
GATCCTCAAGGGCTGGGTCGACCGCGTCTACGCCTGCGGATTTGCCTATGGGGTCGGCGAGCACAGCGACGAGCGATGGG
GTGACCGTTACGGCGAAGGCAATCTGGCCGGCAAGCGCGCGATGCTGATCGTGACCACCGGCGGCTGGGAACAGCACTAC
GGCGCCCGCGGCGTCAACGGGCCGATCGACGACCTGCTGTTTCCGATCCACCACGGCATTCTGTTCTACCCGGGCTACGA
CGTGCTGCCGCCGTTCGTCGTGTATCAGGCCGGCCGTCTCGACCAGGCGGGGTTCGAAATCACCGCCGAGCAGCTGCGCG
AGCGGATGCGCACGCTCGCGACCACGCCGCCGATTCCCTACCGGCGCCAGAACGGCGGCGACTACCTGATCCCGAGCATG
GAGCTGCGCCCCGGTCTGGGCGCCCCCGGCAGCAGCGGCTTTGCACTCCACTTGCGGGACGAGACGGCGGCCCCGCTGTG
A

Upstream 100 bases:

>100_bases
ATCCATTTTTCGGCACAATCATATCGAAACTCAACGCCTACCGGAATAGTCGCGGCCGGTCTACTCGGAGGCTCCGATCA
ATCATCGAGGAGCCACGGCC

Downstream 100 bases:

>100_bases
CAGCGGTCCGCGATACCATTCGCCGGCAGCGGAGATGCAGAAGGTTGTTAACGCTTTCCGGCTAAGCTGCGGCGATGGAC
ATGAGCATGATCAGTGCGGC

Product: NAD(P)H dehydrogenase (quinone)

Products: NAD+; NADP+; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKVLLVFAHPEPLSLNGALRDAAVAELQRQGHEVRISDLYAQNWKPAIDRADFPNLAPDERLLTSAASKASFDAGELTQD
VRAEIDKLLWADVLILQFPLWWFSMPAILKGWVDRVYACGFAYGVGEHSDERWGDRYGEGNLAGKRAMLIVTTGGWEQHY
GARGVNGPIDDLLFPIHHGILFYPGYDVLPPFVVYQAGRLDQAGFEITAEQLRERMRTLATTPPIPYRRQNGGDYLIPSM
ELRPGLGAPGSSGFALHLRDETAAPL

Sequences:

>Translated_266_residues
MKVLLVFAHPEPLSLNGALRDAAVAELQRQGHEVRISDLYAQNWKPAIDRADFPNLAPDERLLTSAASKASFDAGELTQD
VRAEIDKLLWADVLILQFPLWWFSMPAILKGWVDRVYACGFAYGVGEHSDERWGDRYGEGNLAGKRAMLIVTTGGWEQHY
GARGVNGPIDDLLFPIHHGILFYPGYDVLPPFVVYQAGRLDQAGFEITAEQLRERMRTLATTPPIPYRRQNGGDYLIPSM
ELRPGLGAPGSSGFALHLRDETAAPL
>Mature_266_residues
MKVLLVFAHPEPLSLNGALRDAAVAELQRQGHEVRISDLYAQNWKPAIDRADFPNLAPDERLLTSAASKASFDAGELTQD
VRAEIDKLLWADVLILQFPLWWFSMPAILKGWVDRVYACGFAYGVGEHSDERWGDRYGEGNLAGKRAMLIVTTGGWEQHY
GARGVNGPIDDLLFPIHHGILFYPGYDVLPPFVVYQAGRLDQAGFEITAEQLRERMRTLATTPPIPYRRQNGGDYLIPSM
ELRPGLGAPGSSGFALHLRDETAAPL

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=234, Percent_Identity=39.7435897435897, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI4505415, Length=227, Percent_Identity=36.5638766519824, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI70995396, Length=131, Percent_Identity=43.5114503816794, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786231, Length=165, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787129, Length=128, Percent_Identity=34.375, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.2

Molecular weight: Translated: 29540; Mature: 29540

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLVFAHPEPLSLNGALRDAAVAELQRQGHEVRISDLYAQNWKPAIDRADFPNLAPDE
CEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCCCHH
RLLTSAASKASFDAGELTQDVRAEIDKLLWADVLILQFPLWWFSMPAILKGWVDRVYACG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDERWGDRYGEGNLAGKRAMLIVTTGGWEQHYGARGVNGPIDDLLFPIHHGI
HHHCCCCCCCHHHHHHCCCCCCCCCEEEEEEEECCCHHHCCCCCCCCCHHHHHHHHHCCE
LFYPGYDVLPPFVVYQAGRLDQAGFEITAEQLRERMRTLATTPPIPYRRQNGGDYLIPSM
EEECCCHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEECCCC
ELRPGLGAPGSSGFALHLRDETAAPL
CCCCCCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKVLLVFAHPEPLSLNGALRDAAVAELQRQGHEVRISDLYAQNWKPAIDRADFPNLAPDE
CEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCCCHH
RLLTSAASKASFDAGELTQDVRAEIDKLLWADVLILQFPLWWFSMPAILKGWVDRVYACG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDERWGDRYGEGNLAGKRAMLIVTTGGWEQHYGARGVNGPIDDLLFPIHHGI
HHHCCCCCCCHHHHHHCCCCCCCCCEEEEEEEECCCHHHCCCCCCCCCHHHHHHHHHCCE
LFYPGYDVLPPFVVYQAGRLDQAGFEITAEQLRERMRTLATTPPIPYRRQNGGDYLIPSM
EEECCCHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEECCCC
ELRPGLGAPGSSGFALHLRDETAAPL
CCCCCCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; NADPH; H+; acceptor

Specific reaction: NAD(P)H + H+ + acceptor = NAD(P)+ + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]