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The map label for this gene is argD [H]

Identifier: 86747909

GI number: 86747909

Start: 876556

End: 877779

Strand: Direct

Name: argD [H]

Synonym: RPB_0783

Alternate gene names: 86747909

Gene position: 876556-877779 (Clockwise)

Preceding gene: 86747907

Following gene: 86747910

Centisome position: 16.44

GC content: 68.14

Gene sequence:

>1224_bases
ATGTCGAGTGCTAAGTCGAGTGCAGCTACTACGTCCCATCTCCTGCCGGTGTTCGCGAGGGCGGATGTCGCCTTCGAGCG
CGGCGAGGGTGCCTGGCTGATCTCGACCACCGGCGAGCGCTACCTCGATTTCACCAGCGGCGTCGCGGTCAATTCGCTCG
GCCATTGCCATCCGCATCTGGTCGAAGCGTTGCAGCAGCAGGCGACCAAACTGTGGCACATGTCGAACCTGTTCAAGAGT
CCGGACGGCGAGCGCCTCGCCGCGCGGCTGTGCGAGCAGAGCTTCGCCGATTTCGTGTTCTTCGCCAATTCCGGCGCGGA
GGCGATGGAGTGCGCGCTGAAGATGACGCGGCACCACCATTTCTCCAAAGGCAATCCGGAGCGCACCCGGATCATCACCT
TCGCGGGCGCGTTCCACGGCCGCACGCTCGGCACGCTCGCCGCCACCGGCTCGGCGAAGTATCTCGAAGGCTATGGCGAG
CCGCTCGACGGCTTCGACCAAGTGCCGCTCGGCGATCTCGACGCGGTGAAGAAGGCGATCGGCCCGACCACCGCCGGCAT
CCTGATCGAGCCGCTGCAGGGCGAGGGCGGGGTCCGTTCGCCGGAGCCGGCGTTCTTCCGCGCGCTGCGCGATCTGTGCG
ACAGCAATGGCCTGCTGCTGATTTTCGACGAGGTACAGACCGGCATGGGCCGCACCGGCGAGCTGTTCGCTTACCAGCGG
ATCGGCGTGGCGCCCGATATCATGTCGCTGGCCAAGGCGCTCGGCGGCGGTTTCCCGATCGGCGCCTGCCTCGCCACCGC
GGATGCCGCCGAGGGCATGGCGCCGGGTTCGCACGGCTCGACCTTCGGCGGCAATCCGCTCGCCGTCGCCGCCGCCAATG
CGGTGCTCGACGTGATGCTGGAGCCCGGCTTCCTCGATCACGTCCGGCGGATGTCGCTGCTGTTGAAGCAGAAGCTCGCC
GGCATCGTCGATCGCTATCCGCAGGTGCTGAGCGAGATCCGCGGCGAAGGGCTGCTGATCGGCCTCAAGGCGGTGGTGCC
GTCGACCGATCTGGTCGCCGCCCTGCGCGACCAGAATTTGCTCACGGTCGGCGCCGGCGACAACGTCGTGCGGCTGCTGC
CGCCGCTGATCGTCGACGAGGTGGAGATCGACGAGGCGGTGACGCGGCTCGAGCGCGCCTGCGGCGTGTTGTCCGGCCAG
GCCGCGCAGCGGGAGGCGGTGTGA

Upstream 100 bases:

>100_bases
CACGTTTCGTTTCCGGGGTACTTTCGTTTCCGGGGCACGTTGGACCGCGACCGCGCTGACGCGGCCGGGCCGGCGGCCCG
TTTTTCCGATCGGATCGGCC

Downstream 100 bases:

>100_bases
TGAGCAGCGCTACCAATCGTGCGGTGAGTAGTTCCAAGAGTACGATCGAGAGTCCAGCGATGACCAGCGCCCCGAGGCAT
TTCCTCGATCTCACCGAGGT

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT 1 [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSSAKSSAATTSHLLPVFARADVAFERGEGAWLISTTGERYLDFTSGVAVNSLGHCHPHLVEALQQQATKLWHMSNLFKS
PDGERLAARLCEQSFADFVFFANSGAEAMECALKMTRHHHFSKGNPERTRIITFAGAFHGRTLGTLAATGSAKYLEGYGE
PLDGFDQVPLGDLDAVKKAIGPTTAGILIEPLQGEGGVRSPEPAFFRALRDLCDSNGLLLIFDEVQTGMGRTGELFAYQR
IGVAPDIMSLAKALGGGFPIGACLATADAAEGMAPGSHGSTFGGNPLAVAAANAVLDVMLEPGFLDHVRRMSLLLKQKLA
GIVDRYPQVLSEIRGEGLLIGLKAVVPSTDLVAALRDQNLLTVGAGDNVVRLLPPLIVDEVEIDEAVTRLERACGVLSGQ
AAQREAV

Sequences:

>Translated_407_residues
MSSAKSSAATTSHLLPVFARADVAFERGEGAWLISTTGERYLDFTSGVAVNSLGHCHPHLVEALQQQATKLWHMSNLFKS
PDGERLAARLCEQSFADFVFFANSGAEAMECALKMTRHHHFSKGNPERTRIITFAGAFHGRTLGTLAATGSAKYLEGYGE
PLDGFDQVPLGDLDAVKKAIGPTTAGILIEPLQGEGGVRSPEPAFFRALRDLCDSNGLLLIFDEVQTGMGRTGELFAYQR
IGVAPDIMSLAKALGGGFPIGACLATADAAEGMAPGSHGSTFGGNPLAVAAANAVLDVMLEPGFLDHVRRMSLLLKQKLA
GIVDRYPQVLSEIRGEGLLIGLKAVVPSTDLVAALRDQNLLTVGAGDNVVRLLPPLIVDEVEIDEAVTRLERACGVLSGQ
AAQREAV
>Mature_406_residues
SSAKSSAATTSHLLPVFARADVAFERGEGAWLISTTGERYLDFTSGVAVNSLGHCHPHLVEALQQQATKLWHMSNLFKSP
DGERLAARLCEQSFADFVFFANSGAEAMECALKMTRHHHFSKGNPERTRIITFAGAFHGRTLGTLAATGSAKYLEGYGEP
LDGFDQVPLGDLDAVKKAIGPTTAGILIEPLQGEGGVRSPEPAFFRALRDLCDSNGLLLIFDEVQTGMGRTGELFAYQRI
GVAPDIMSLAKALGGGFPIGACLATADAAEGMAPGSHGSTFGGNPLAVAAANAVLDVMLEPGFLDHVRRMSLLLKQKLAG
IVDRYPQVLSEIRGEGLLIGLKAVVPSTDLVAALRDQNLLTVGAGDNVVRLLPPLIVDEVEIDEAVTRLERACGVLSGQA
AQREAV

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=394, Percent_Identity=34.2639593908629, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=31.4942528735632, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=35, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=27.5943396226415, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=28.3653846153846, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=27.5064267352185, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226442705, Length=429, Percent_Identity=27.039627039627, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI188536080, Length=410, Percent_Identity=26.5853658536585, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI38679950, Length=410, Percent_Identity=26.5853658536585, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI38679946, Length=410, Percent_Identity=26.5853658536585, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1789759, Length=402, Percent_Identity=43.7810945273632, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=43.0412371134021, Blast_Score=307, Evalue=7e-85,
Organism=Escherichia coli, GI145693181, Length=385, Percent_Identity=36.1038961038961, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789016, Length=409, Percent_Identity=34.4743276283619, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=34.25, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1786991, Length=400, Percent_Identity=31, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=32.3717948717949, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=373, Percent_Identity=33.5120643431635, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=445, Percent_Identity=28.7640449438202, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI25144274, Length=261, Percent_Identity=34.4827586206897, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=27.8688524590164, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=436, Percent_Identity=25.6880733944954, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=29.375, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=386, Percent_Identity=37.3056994818653, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323470, Length=421, Percent_Identity=33.729216152019, Blast_Score=209, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=301, Percent_Identity=28.2392026578073, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=438, Percent_Identity=24.4292237442922, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357415, Length=408, Percent_Identity=32.5980392156863, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI161085790, Length=438, Percent_Identity=29.9086757990868, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=29.8850574712644, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=29.6650717703349, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=26.463700234192, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=26.463700234192, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=26.463700234192, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43088; Mature: 42957

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAKSSAATTSHLLPVFARADVAFERGEGAWLISTTGERYLDFTSGVAVNSLGHCHPHL
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHCCCHHHCCCCCCHHH
VEALQQQATKLWHMSNLFKSPDGERLAARLCEQSFADFVFFANSGAEAMECALKMTRHHH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHC
FSKGNPERTRIITFAGAFHGRTLGTLAATGSAKYLEGYGEPLDGFDQVPLGDLDAVKKAI
CCCCCCCCEEEEEEECCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
GPTTAGILIEPLQGEGGVRSPEPAFFRALRDLCDSNGLLLIFDEVQTGMGRTGELFAYQR
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEEEEHH
IGVAPDIMSLAKALGGGFPIGACLATADAAEGMAPGSHGSTFGGNPLAVAAANAVLDVML
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
EPGFLDHVRRMSLLLKQKLAGIVDRYPQVLSEIRGEGLLIGLKAVVPSTDLVAALRDQNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCHHHHHHHCCCCE
LTVGAGDNVVRLLPPLIVDEVEIDEAVTRLERACGVLSGQAAQREAV
EEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure 
SSAKSSAATTSHLLPVFARADVAFERGEGAWLISTTGERYLDFTSGVAVNSLGHCHPHL
CCCCCHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCHHHHHHCCCHHHCCCCCCHHH
VEALQQQATKLWHMSNLFKSPDGERLAARLCEQSFADFVFFANSGAEAMECALKMTRHHH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHC
FSKGNPERTRIITFAGAFHGRTLGTLAATGSAKYLEGYGEPLDGFDQVPLGDLDAVKKAI
CCCCCCCCEEEEEEECCCCCCHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
GPTTAGILIEPLQGEGGVRSPEPAFFRALRDLCDSNGLLLIFDEVQTGMGRTGELFAYQR
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEEEEHH
IGVAPDIMSLAKALGGGFPIGACLATADAAEGMAPGSHGSTFGGNPLAVAAANAVLDVML
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
EPGFLDHVRRMSLLLKQKLAGIVDRYPQVLSEIRGEGLLIGLKAVVPSTDLVAALRDQNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCHHHHHHHCCCCE
LTVGAGDNVVRLLPPLIVDEVEIDEAVTRLERACGVLSGQAAQREAV
EEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]