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The map label for this gene is fecD [C]

Identifier: 86747858

GI number: 86747858

Start: 822074

End: 823099

Strand: Direct

Name: fecD [C]

Synonym: RPB_0732

Alternate gene names: 86747858

Gene position: 822074-823099 (Clockwise)

Preceding gene: 86747857

Following gene: 86747859

Centisome position: 15.42

GC content: 70.57

Gene sequence:

>1026_bases
ATGACGATGCGTCCAAATCCCGCGTCACGCGCGGCGGCGGTCACGGCCGCGCTCATGATCGTGGTCGGCCTGCTCGCGCT
CGGCTCGCTCGGCGTCGGCCCGGTGAAGCTGTCGCCGCTCGCCGTGATCGATGCGCTGATCGGCCGTGGCGGCGAGGTGC
AGCAGATCATCGTGCAGCAGATTCGCCTCCCGCGCGCCATCCTGGCGCTGGCGATCGGCGGCATTCTCGGCCTGTCCGGC
GCGGCGCTGCAGGGCCTGCTGCGCAATCCGCTGGCGTCGCCGTCGCTGTTCGGCGCGCCGCAATCGGCGGCGTTCGGCGC
CGTGCTGATCATTGCGCTGGGCTGGGCCGATGTCCGCTCCTATGCGTTGCCGGTCGCCGGCATCACCATGGCGTTCGTCT
CGGTGTTCGTGCTGCTCACGGTCGCCGGCCGCAGCGCCAGCCTGCTGCTGCTGATCCTCGCGGGACTGGCGATCTCGAGC
CTCGCCGGTGCGGCGACCGCGCTGGTGATGAATTTGTCGAACAATCCGTTCGCCAGCCTCGAAATCGCGTTCTGGCTGCT
CGGCTCGCTGGAGGACCGCAGCTTCCGCCACGTCGCATTGGCGCTGCCCTTCATCGTCGTAGGCGCCGCGCTGCTGTTCA
GCCAGCGCGCCGCGTTCCGGGCGCTCAGCCTCGGCGAGGAAACCGCGCAGAGTCTCGGCGTCGACGTCGCGCGCCTGCGG
CTGATCGTGATCGCCGGCACGGCGCTCGGCGTCGGCGGCGCGGTGTCGGTGTCGGGCACGATCGGCTTCATCGGCCTGGT
GGCGCCGCATCTGGTGCGGCCGCTGATCGGCCACGATCCGGCGCGCTTGTTGATCCCGAGCGCGCTCGCCGGCGCCGCGC
TGCTGCTCGCCGCCGACATCGCGGTGCGGATCATTCCGTCGACCACCGACATCAAGGTCGGCGTGCTGACCTCGATCATC
GGCGTGCCGTTCTTCCTGTATCTGATCATGCGCGAGCGCCGCGCGCTGGGCGGAGGCGTCGCATGA

Upstream 100 bases:

>100_bases
CTGTTCGTCGCGAGCTGGATCGTCTCGACCATCATCTACCGCGCCAATGGCTATCACCGGCTCGACGAACGCGCGCCCGT
CGTGCAGAAATGACCGCCAT

Downstream 100 bases:

>100_bases
GCGGACACGGCTTCCTCGCCGCGCGAAACCTCGGCGTCGCGCTGTCCGGCCGGCAGGTGCTGCACGGCGTCTCGCTGGAT
CTCGCGCGCGGCCATCTGGT

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTMRPNPASRAAAVTAALMIVVGLLALGSLGVGPVKLSPLAVIDALIGRGGEVQQIIVQQIRLPRAILALAIGGILGLSG
AALQGLLRNPLASPSLFGAPQSAAFGAVLIIALGWADVRSYALPVAGITMAFVSVFVLLTVAGRSASLLLLILAGLAISS
LAGAATALVMNLSNNPFASLEIAFWLLGSLEDRSFRHVALALPFIVVGAALLFSQRAAFRALSLGEETAQSLGVDVARLR
LIVIAGTALGVGGAVSVSGTIGFIGLVAPHLVRPLIGHDPARLLIPSALAGAALLLAADIAVRIIPSTTDIKVGVLTSII
GVPFFLYLIMRERRALGGGVA

Sequences:

>Translated_341_residues
MTMRPNPASRAAAVTAALMIVVGLLALGSLGVGPVKLSPLAVIDALIGRGGEVQQIIVQQIRLPRAILALAIGGILGLSG
AALQGLLRNPLASPSLFGAPQSAAFGAVLIIALGWADVRSYALPVAGITMAFVSVFVLLTVAGRSASLLLLILAGLAISS
LAGAATALVMNLSNNPFASLEIAFWLLGSLEDRSFRHVALALPFIVVGAALLFSQRAAFRALSLGEETAQSLGVDVARLR
LIVIAGTALGVGGAVSVSGTIGFIGLVAPHLVRPLIGHDPARLLIPSALAGAALLLAADIAVRIIPSTTDIKVGVLTSII
GVPFFLYLIMRERRALGGGVA
>Mature_340_residues
TMRPNPASRAAAVTAALMIVVGLLALGSLGVGPVKLSPLAVIDALIGRGGEVQQIIVQQIRLPRAILALAIGGILGLSGA
ALQGLLRNPLASPSLFGAPQSAAFGAVLIIALGWADVRSYALPVAGITMAFVSVFVLLTVAGRSASLLLLILAGLAISSL
AGAATALVMNLSNNPFASLEIAFWLLGSLEDRSFRHVALALPFIVVGAALLFSQRAAFRALSLGEETAQSLGVDVARLRL
IVIAGTALGVGGAVSVSGTIGFIGLVAPHLVRPLIGHDPARLLIPSALAGAALLLAADIAVRIIPSTTDIKVGVLTSIIG
VPFFLYLIMRERRALGGGVA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=296, Percent_Identity=35.1351351351351, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790741, Length=297, Percent_Identity=34.006734006734, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788004, Length=292, Percent_Identity=34.2465753424658, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786805, Length=310, Percent_Identity=37.0967741935484, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786347, Length=276, Percent_Identity=31.8840579710145, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786804, Length=280, Percent_Identity=33.2142857142857, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34618; Mature: 34487

Theoretical pI: Translated: 11.92; Mature: 11.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRPNPASRAAAVTAALMIVVGLLALGSLGVGPVKLSPLAVIDALIGRGGEVQQIIVQQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHCCCCHHHHHHHHH
IRLPRAILALAIGGILGLSGAALQGLLRNPLASPSLFGAPQSAAFGAVLIIALGWADVRS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YALPVAGITMAFVSVFVLLTVAGRSASLLLLILAGLAISSLAGAATALVMNLSNNPFASL
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
EIAFWLLGSLEDRSFRHVALALPFIVVGAALLFSQRAAFRALSLGEETAQSLGVDVARLR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHE
LIVIAGTALGVGGAVSVSGTIGFIGLVAPHLVRPLIGHDPARLLIPSALAGAALLLAADI
EHEEECCHHCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AVRIIPSTTDIKVGVLTSIIGVPFFLYLIMRERRALGGGVA
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMRPNPASRAAAVTAALMIVVGLLALGSLGVGPVKLSPLAVIDALIGRGGEVQQIIVQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHCCCCHHHHHHHHH
IRLPRAILALAIGGILGLSGAALQGLLRNPLASPSLFGAPQSAAFGAVLIIALGWADVRS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YALPVAGITMAFVSVFVLLTVAGRSASLLLLILAGLAISSLAGAATALVMNLSNNPFASL
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHH
EIAFWLLGSLEDRSFRHVALALPFIVVGAALLFSQRAAFRALSLGEETAQSLGVDVARLR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHE
LIVIAGTALGVGGAVSVSGTIGFIGLVAPHLVRPLIGHDPARLLIPSALAGAALLLAADI
EHEEECCHHCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AVRIIPSTTDIKVGVLTSIIGVPFFLYLIMRERRALGGGVA
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]