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The map label for this gene is nudC [H]

Identifier: 86747796

GI number: 86747796

Start: 754531

End: 755463

Strand: Direct

Name: nudC [H]

Synonym: RPB_0670

Alternate gene names: 86747796

Gene position: 754531-755463 (Clockwise)

Preceding gene: 86747795

Following gene: 86747797

Centisome position: 14.15

GC content: 66.35

Gene sequence:

>933_bases
ATGAGCAGCGCCTTTCCGCTCGGCCAGCCGGCCTTCGTCAGCAACATCCTCGACCGCGCCGCGCATCTGCGCCGCGACGA
TTCCAAGCTGATGGCAATGGAGGACAAAAGCGACACCCGCGCCTATGTGGTGCATCGCGATTCGCTGGTGGTGAAGCACG
AGGACGGCGGCCCGCGCGCGCTGCTGTCGATCAAGGAGGCGCTGTCGCTCGGCGCCAATCCCGGCACGATCTTCCTCGGC
CTGCGCGACGGCGCGGCGGTGTTCGGCATGGGCATCGGCGCTACGGCAGTCGAGACGCTGATGACGCGCAGCGACGCCGG
CATCGCCGAGCTGCGCGGCATGGCGATGCAGGGCATCCTGCCGCCGGAACAGCTGTCGGCGATCGCGATGGCGAAATCGA
TGGTCAGCTGGCACCAGCGCCACGGCTATTGCGCCAATTGCGGCACCCGCACGGCGATGACGCAGGGCGGCTGGAAGCGC
GACTGCCCGAACTGCAAGGCCGAGCATTTTCCGCGCACCGACCCGGTGGTGATCATGCTGGTGACGTCCGGCGACAAATG
CCTGCTCGGCCGGCAGAAGCCGTTTCCGGCCGGGATGTATTCGTGCCTCGCCGGCTTCGTCGAGGCGGCGGAGACGATCG
AGGATGCGGTGCGTCGCGAGATTTTTGAGGAATCCGGCATCCGCTGTTCCGAGGTGCGCTACTACATGACGCAGCCGTGG
CCGTACCCATCCTCGCTGATGATCGGTTGTACGGCGATCGCCACGACGGAAGACATCACCATCGATTTCACCGAACTCGA
AGATGCGCGCTGGTTCTCGCGCGACGAGGCCGCCGCGATGCTCAATCGCCAGCATCCGGACGGCCTGGTCGGGCCGCACC
CGTTCGCGATCGCGCATCATCTGGTCGGCCGCTGGCTGGAGCAGACATCATGA

Upstream 100 bases:

>100_bases
CGCCCGGTGTGGGGCGTGGTGCCGGCGCTGCCGCACGACGCCGAGGAAGTGCAGCACTTCATCAGCGCGCTGCGGCGCAA
GATCTGGCTGGGCTGAGCCG

Downstream 100 bases:

>100_bases
CGAACACCGCAAAGCCCAAGCCGCGGATTCTCTGCGTCGGCATTCCGGTCCGCGACCTCACCTTCCGGATCGAGGCGGTG
CCGGGCCGCGGCAACAAGAT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSSAFPLGQPAFVSNILDRAAHLRRDDSKLMAMEDKSDTRAYVVHRDSLVVKHEDGGPRALLSIKEALSLGANPGTIFLG
LRDGAAVFGMGIGATAVETLMTRSDAGIAELRGMAMQGILPPEQLSAIAMAKSMVSWHQRHGYCANCGTRTAMTQGGWKR
DCPNCKAEHFPRTDPVVIMLVTSGDKCLLGRQKPFPAGMYSCLAGFVEAAETIEDAVRREIFEESGIRCSEVRYYMTQPW
PYPSSLMIGCTAIATTEDITIDFTELEDARWFSRDEAAAMLNRQHPDGLVGPHPFAIAHHLVGRWLEQTS

Sequences:

>Translated_310_residues
MSSAFPLGQPAFVSNILDRAAHLRRDDSKLMAMEDKSDTRAYVVHRDSLVVKHEDGGPRALLSIKEALSLGANPGTIFLG
LRDGAAVFGMGIGATAVETLMTRSDAGIAELRGMAMQGILPPEQLSAIAMAKSMVSWHQRHGYCANCGTRTAMTQGGWKR
DCPNCKAEHFPRTDPVVIMLVTSGDKCLLGRQKPFPAGMYSCLAGFVEAAETIEDAVRREIFEESGIRCSEVRYYMTQPW
PYPSSLMIGCTAIATTEDITIDFTELEDARWFSRDEAAAMLNRQHPDGLVGPHPFAIAHHLVGRWLEQTS
>Mature_309_residues
SSAFPLGQPAFVSNILDRAAHLRRDDSKLMAMEDKSDTRAYVVHRDSLVVKHEDGGPRALLSIKEALSLGANPGTIFLGL
RDGAAVFGMGIGATAVETLMTRSDAGIAELRGMAMQGILPPEQLSAIAMAKSMVSWHQRHGYCANCGTRTAMTQGGWKRD
CPNCKAEHFPRTDPVVIMLVTSGDKCLLGRQKPFPAGMYSCLAGFVEAAETIEDAVRREIFEESGIRCSEVRYYMTQPWP
YPSSLMIGCTAIATTEDITIDFTELEDARWFSRDEAAAMLNRQHPDGLVGPHPFAIAHHLVGRWLEQTS

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=337, Percent_Identity=37.6854599406528, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI50593112, Length=220, Percent_Identity=38.6363636363636, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI48994995, Length=144, Percent_Identity=36.8055555555556, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71986510, Length=214, Percent_Identity=30.3738317757009, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI212645999, Length=214, Percent_Identity=30.3738317757009, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321371, Length=225, Percent_Identity=35.1111111111111, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 33959; Mature: 33828

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAFPLGQPAFVSNILDRAAHLRRDDSKLMAMEDKSDTRAYVVHRDSLVVKHEDGGPRA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECEEEEEECCCCCHH
LLSIKEALSLGANPGTIFLGLRDGAAVFGMGIGATAVETLMTRSDAGIAELRGMAMQGIL
HHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHCCC
PPEQLSAIAMAKSMVSWHQRHGYCANCGTRTAMTQGGWKRDCPNCKAEHFPRTDPVVIML
CHHHHHHHHHHHHHHHHHHHCCEECCCCCCCHHCCCCCCCCCCCCCHHCCCCCCCEEEEE
VTSGDKCLLGRQKPFPAGMYSCLAGFVEAAETIEDAVRREIFEESGIRCSEVRYYMTQPW
EECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCC
PYPSSLMIGCTAIATTEDITIDFTELEDARWFSRDEAAAMLNRQHPDGLVGPHPFAIAHH
CCCCHHHEEEEEEECCCCEEEEEEECCCHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
LVGRWLEQTS
HHHHHHHHCC
>Mature Secondary Structure 
SSAFPLGQPAFVSNILDRAAHLRRDDSKLMAMEDKSDTRAYVVHRDSLVVKHEDGGPRA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEEECEEEEEECCCCCHH
LLSIKEALSLGANPGTIFLGLRDGAAVFGMGIGATAVETLMTRSDAGIAELRGMAMQGIL
HHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHCCC
PPEQLSAIAMAKSMVSWHQRHGYCANCGTRTAMTQGGWKRDCPNCKAEHFPRTDPVVIML
CHHHHHHHHHHHHHHHHHHHCCEECCCCCCCHHCCCCCCCCCCCCCHHCCCCCCCEEEEE
VTSGDKCLLGRQKPFPAGMYSCLAGFVEAAETIEDAVRREIFEESGIRCSEVRYYMTQPW
EECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCC
PYPSSLMIGCTAIATTEDITIDFTELEDARWFSRDEAAAMLNRQHPDGLVGPHPFAIAHH
CCCCHHHEEEEEEECCCCEEEEEEECCCHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
LVGRWLEQTS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]