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The map label for this gene is coaA

Identifier: 86747537

GI number: 86747537

Start: 454035

End: 454991

Strand: Direct

Name: coaA

Synonym: RPB_0411

Alternate gene names: 86747537

Gene position: 454035-454991 (Clockwise)

Preceding gene: 86747536

Following gene: 86747548

Centisome position: 8.52

GC content: 64.89

Gene sequence:

>957_bases
ATGGATGCCAGGTCGGAACTGCACCACTACAACCCGTATCGGGTGTTCTCGCGGTCGGAATGGGCCAATCTTCGCCAGGA
CACGCCGATGACGCTCGACGCGGGCGAGGTTTCGACGCTGCGCTCGCTGCACGACCGGCTCGACCTCAGCGAGGTCGAGG
AGATCTATCTGCCGATGTCGCGGCTGCTGTCGATCCATGTCGGCGCGATGCAGCAGCTTTACTACGCGCAGCGCCGCTTC
CTCGGCGTGGTCGAGCGCAAGATGCCTTACATCATCGGCGTCGCCGGTTCGGTCGCGGTCGGCAAATCGACCACTGCGCG
CGTGCTGCAGGCGCTCTTGGCGCGCTGGTCGCCGCGGCCCAAGGTCGATCTGATCACCACCGACGGCTTCCTGCATCCCA
ACGCGGTGCTGGAGCGCGCCGGGCTGATGCAGAAGAAGGGCTTTCCGGAAAGCTACGACCTGCCGGCACTGCTGGCGTTT
CTCAGTGATATCAAGTCAGGCCGCCGCAAGGTCCGCGCGCCGATCTATTCGCATCTGACCTACGACATCGTGCCGAACAA
ATTCGCGGTGGTGGACCGGCCCGACATCCTGATCGTCGAAGGCGTCAACGTGCTGCAAACCGGCCGGCTGCCGCGCGACG
GCAAGGCGGTGCCGGTGGTGTCCGACTTCTTCGATTTCTCGGTGTATATCGACGCCGACGAACCGGTGCTGCGCGATTGG
TACATCCGGCGCTTCCTGGCGCTGCGTGACACCGCGTTTCACGATCCGCGATCCTACTTCCACCGCTACGCGCCGCTGTC
CGACGAAGAGGCGACCGCGACCGCGATCGCGATCTGGGAACGGACGAACCTGGCCAATCTCGAGGACAACATCCTGCCGA
CCCGGCCGCGGGCGACACTGATCCTGAAGAAGGGCGCCGACCACGTCGTGGATTCGGTGGCGCTGCGGCGGCTGTGA

Upstream 100 bases:

>100_bases
CCGAAAACGGTTCGCGTCTTGGAAACGCGTCCGAGAAATTCCTACCGGCCGCAACGGCCGCAAAAGCAACAAGAACCAGA
AACGAAGCGAGGACGACGCG

Downstream 100 bases:

>100_bases
TCTCCGCGGCCTGTCATCCGCGGGCTTGACCCGCGGATCGATCGCGCGCGAACCGCGCCGTTCAAGGATTCCTGCGAAGA
CGATGGATTGCCGGGTCGGG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDARSELHHYNPYRVFSRSEWANLRQDTPMTLDAGEVSTLRSLHDRLDLSEVEEIYLPMSRLLSIHVGAMQQLYYAQRRF
LGVVERKMPYIIGVAGSVAVGKSTTARVLQALLARWSPRPKVDLITTDGFLHPNAVLERAGLMQKKGFPESYDLPALLAF
LSDIKSGRRKVRAPIYSHLTYDIVPNKFAVVDRPDILIVEGVNVLQTGRLPRDGKAVPVVSDFFDFSVYIDADEPVLRDW
YIRRFLALRDTAFHDPRSYFHRYAPLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHVVDSVALRRL

Sequences:

>Translated_318_residues
MDARSELHHYNPYRVFSRSEWANLRQDTPMTLDAGEVSTLRSLHDRLDLSEVEEIYLPMSRLLSIHVGAMQQLYYAQRRF
LGVVERKMPYIIGVAGSVAVGKSTTARVLQALLARWSPRPKVDLITTDGFLHPNAVLERAGLMQKKGFPESYDLPALLAF
LSDIKSGRRKVRAPIYSHLTYDIVPNKFAVVDRPDILIVEGVNVLQTGRLPRDGKAVPVVSDFFDFSVYIDADEPVLRDW
YIRRFLALRDTAFHDPRSYFHRYAPLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHVVDSVALRRL
>Mature_318_residues
MDARSELHHYNPYRVFSRSEWANLRQDTPMTLDAGEVSTLRSLHDRLDLSEVEEIYLPMSRLLSIHVGAMQQLYYAQRRF
LGVVERKMPYIIGVAGSVAVGKSTTARVLQALLARWSPRPKVDLITTDGFLHPNAVLERAGLMQKKGFPESYDLPALLAF
LSDIKSGRRKVRAPIYSHLTYDIVPNKFAVVDRPDILIVEGVNVLQTGRLPRDGKAVPVVSDFFDFSVYIDADEPVLRDW
YIRRFLALRDTAFHDPRSYFHRYAPLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHVVDSVALRRL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=307, Percent_Identity=55.700325732899, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_RHOP2 (Q2J338)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_484033.1
- ProteinModelPortal:   Q2J338
- SMR:   Q2J338
- STRING:   Q2J338
- GeneID:   3908849
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_0411
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   RPAL316058:RPB_0411-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 36183; Mature: 36183

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARSELHHYNPYRVFSRSEWANLRQDTPMTLDAGEVSTLRSLHDRLDLSEVEEIYLPMS
CCCHHHHCCCCCEEEECCCHHHHHCCCCCCEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
RLLSIHVGAMQQLYYAQRRFLGVVERKMPYIIGVAGSVAVGKSTTARVLQALLARWSPRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCC
KVDLITTDGFLHPNAVLERAGLMQKKGFPESYDLPALLAFLSDIKSGRRKVRAPIYSHLT
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHEE
YDIVPNKFAVVDRPDILIVEGVNVLQTGRLPRDGKAVPVVSDFFDFSVYIDADEPVLRDW
EEECCCEEEEECCCCEEEECCCCHHHCCCCCCCCCCCCEEHHCCCEEEEEECCCCHHHHH
YIRRFLALRDTAFHDPRSYFHRYAPLSDEEATATAIAIWERTNLANLEDNILPTRPRATL
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCEEE
ILKKGADHVVDSVALRRL
EEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MDARSELHHYNPYRVFSRSEWANLRQDTPMTLDAGEVSTLRSLHDRLDLSEVEEIYLPMS
CCCHHHHCCCCCEEEECCCHHHHHCCCCCCEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
RLLSIHVGAMQQLYYAQRRFLGVVERKMPYIIGVAGSVAVGKSTTARVLQALLARWSPRP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCC
KVDLITTDGFLHPNAVLERAGLMQKKGFPESYDLPALLAFLSDIKSGRRKVRAPIYSHLT
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHEE
YDIVPNKFAVVDRPDILIVEGVNVLQTGRLPRDGKAVPVVSDFFDFSVYIDADEPVLRDW
EEECCCEEEEECCCCEEEECCCCHHHCCCCCCCCCCCCEEHHCCCEEEEEECCCCHHHHH
YIRRFLALRDTAFHDPRSYFHRYAPLSDEEATATAIAIWERTNLANLEDNILPTRPRATL
HHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCEEE
ILKKGADHVVDSVALRRL
EEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA