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The map label for this gene is dnaQ [H]

Identifier: 86747524

GI number: 86747524

Start: 442905

End: 443600

Strand: Direct

Name: dnaQ [H]

Synonym: RPB_0398

Alternate gene names: 86747524

Gene position: 442905-443600 (Clockwise)

Preceding gene: 86747523

Following gene: 86747526

Centisome position: 8.31

GC content: 66.24

Gene sequence:

>696_bases
ATGCGCGAAATCGTTCTCGATACCGAAACCACCGGCCTCGATCCGCTGCGCGGCGACCGGCTGGTCGAGATCGGCTGTGT
CGAAATCTACAACCGGATGCCAACCGGGCAGGTCTATCACCAATACATCAATCCCGAGCGCGACATGCCGGCCGAGGCCT
TCGCGGTGCACGGGCTGTCCAGCGAGTTTCTGGCCGACAAGCCGGTCTTTGCGCAGGTCGCCGACGCGTTCATCGACTTC
ATCGGCGATGCGCCGCTGGTGATCCACAACGCTTCGTTCGACATCGGCTTCATCAACGCCGAACTGGCGCGGCTGTCGCG
GGCGGCGATCCCGCGCGAGCGGCTGGTCGATACGCTGCTGCTGGCGCGGCGCAAGCATCCCGGCGTGTCGAACCGGCTCG
ACGATCTGTGCTCGCGCTATGCGATCGACAATTCGCGCCGCACCAAGCACGGCGCGCTGCTCGACGCCGAGCTGCTGGCC
GAAGTCTATATCGATCTGATCGGCGCGCGGCAGTCGCAACTGATTCTGGCGGAAGTTCCGTCGGAGCGCAGCGGCGCCGG
CGGCGACACGCCGCGCCGGCAGCGTTCGATCGCGCTGACGCCTCGCGTCACCGATGCGGACCTCGAGGCCCACCGCGCTT
TCATCGCCCTGATGGGCGACAAGGCGATCTGGAACGAATACACGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GATCCGGTGCGCGCGCAGATCCGCGAAATCCTCGACGCGGCTGCTAGGATGCCTCGCCGGCGGCCGTGATTCGCCGGCGA
CAACCGGCGGCCCTTCTGCA

Downstream 100 bases:

>100_bases
GCGGCGCGGATCCCCACGGCCCACACGCCTGGGCTTGTCCCGGGCATTCCCGTCTCGATGCATCCACCCTGAAAACGTCA
ATGGCCGGGACAAGCCTGGC

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MREIVLDTETTGLDPLRGDRLVEIGCVEIYNRMPTGQVYHQYINPERDMPAEAFAVHGLSSEFLADKPVFAQVADAFIDF
IGDAPLVIHNASFDIGFINAELARLSRAAIPRERLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYIDLIGARQSQLILAEVPSERSGAGGDTPRRQRSIALTPRVTDADLEAHRAFIALMGDKAIWNEYTAAA

Sequences:

>Translated_231_residues
MREIVLDTETTGLDPLRGDRLVEIGCVEIYNRMPTGQVYHQYINPERDMPAEAFAVHGLSSEFLADKPVFAQVADAFIDF
IGDAPLVIHNASFDIGFINAELARLSRAAIPRERLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYIDLIGARQSQLILAEVPSERSGAGGDTPRRQRSIALTPRVTDADLEAHRAFIALMGDKAIWNEYTAAA
>Mature_231_residues
MREIVLDTETTGLDPLRGDRLVEIGCVEIYNRMPTGQVYHQYINPERDMPAEAFAVHGLSSEFLADKPVFAQVADAFIDF
IGDAPLVIHNASFDIGFINAELARLSRAAIPRERLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYIDLIGARQSQLILAEVPSERSGAGGDTPRRQRSIALTPRVTDADLEAHRAFIALMGDKAIWNEYTAAA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=236, Percent_Identity=45.3389830508475, Blast_Score=198, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25564; Mature: 25564

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVLDTETTGLDPLRGDRLVEIGCVEIYNRMPTGQVYHQYINPERDMPAEAFAVHGLS
CCCEEECCCCCCCCCCCCCCEEEEHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHCCCC
SEFLADKPVFAQVADAFIDFIGDAPLVIHNASFDIGFINAELARLSRAAIPRERLVDTLL
HHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHCCCHHHHHHHHH
LARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLAEVYIDLIGARQSQLILAEVP
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
SERSGAGGDTPRRQRSIALTPRVTDADLEAHRAFIALMGDKAIWNEYTAAA
CCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MREIVLDTETTGLDPLRGDRLVEIGCVEIYNRMPTGQVYHQYINPERDMPAEAFAVHGLS
CCCEEECCCCCCCCCCCCCCEEEEHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHCCCC
SEFLADKPVFAQVADAFIDFIGDAPLVIHNASFDIGFINAELARLSRAAIPRERLVDTLL
HHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHCCCHHHHHHHHH
LARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLAEVYIDLIGARQSQLILAEVP
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
SERSGAGGDTPRRQRSIALTPRVTDADLEAHRAFIALMGDKAIWNEYTAAA
CCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]