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The map label for this gene is yycF [H]

Identifier: 86747507

GI number: 86747507

Start: 422148

End: 422834

Strand: Reverse

Name: yycF [H]

Synonym: RPB_0381

Alternate gene names: 86747507

Gene position: 422834-422148 (Counterclockwise)

Preceding gene: 86747509

Following gene: 86747506

Centisome position: 7.93

GC content: 65.5

Gene sequence:

>687_bases
ATGCCGAACGCCCGCAAGATCCTGATCGTGGACGACGACACCGATCTGCGAGACGCGCTGGTCGAGCAATTGTCGCTGCA
CGAGGAGTTCGAGGCCTCCGCGGTCGACACTGGCGCCAAAGGCGTGCAGTCGGCCAAGGCGAATTCGCCCGACCTGGTGC
TGATGGATGTCGGCCTGCCCGACACCGACGGCCGCGAGGTGGTGCGCAGCTTGCGCAAGGGCGGCTTCAAGGCGCCGATC
ATCATGCTGACCGGGCACGACACCGACTCCGACACGATTCTCGGGCTGGAGAGTGGCGCCAACGACTACGTCGCCAAGCC
GTTCCGCTTCGCCGTGCTGCTGGCGCGGATCCGCGCCCAGCTGCGCCAGCATGAAGCCAGCGAGGACGCGGTGTTCACCG
TCGGCCCCTACAGCTTCCGCCCCGGCTCCAAGATGCTGACCGGCGCCAACGCCAAGAAGGTGCGGCTGACCGAGAAGGAA
ACCGCGATCCTGCGCTTCCTGTACCGCGCCGGTCAGGCGCCGGTGTCGCGCGAGACGCTGCTGCAGGAAGTCTGGGGCTA
TAATTCCGGCGTGACCACCCACACGCTCGAGACCCACATTTACCGACTTCGCCAAAAGATCGAGAAGGATGCGGCGAATC
CGGAGATTCTGGTGACCGAGGCCGGTGGCTACAAACTCGTGCCGTGA

Upstream 100 bases:

>100_bases
GATCTGCGATACAATCGCGCTCGATTGCTGCGCATGATTTGGAAAGGCGCCCTCCGCCGCCCCGGCTGGAGCCGCGCGCA
AGACCCGAAGGACATCGCCT

Downstream 100 bases:

>100_bases
TACCAATAGGGGCCGAATCGTCGCCATAGCCTTGGCGCGTCCCGTTCTCTGACCGGTCCCTGATGTCGATCGAAGATGAT
GTTGCCCTGCTCGAGCGCGT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPNARKILIVDDDTDLRDALVEQLSLHEEFEASAVDTGAKGVQSAKANSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPI
IMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKE
TAILRFLYRAGQAPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP

Sequences:

>Translated_228_residues
MPNARKILIVDDDTDLRDALVEQLSLHEEFEASAVDTGAKGVQSAKANSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPI
IMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKE
TAILRFLYRAGQAPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP
>Mature_227_residues
PNARKILIVDDDTDLRDALVEQLSLHEEFEASAVDTGAKGVQSAKANSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPII
MLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKET
AILRFLYRAGQAPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=37.219730941704, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=34.6320346320346, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.8888888888889, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.0807174887892, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.5132743362832, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=29.646017699115, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=205, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.5555555555556, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=30.9012875536481, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=26.9406392694064, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=32.9004329004329, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=30.9322033898305, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.5126050420168, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=30.5084745762712, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25062; Mature: 24931

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNARKILIVDDDTDLRDALVEQLSLHEEFEASAVDTGAKGVQSAKANSPDLVLMDVGLP
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCC
DTDGREVVRSLRKGGFKAPIIMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHH
LRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKETAILRFLYRAGQAPVSRETL
HHHCCCCCCCEEEECCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECC
>Mature Secondary Structure 
PNARKILIVDDDTDLRDALVEQLSLHEEFEASAVDTGAKGVQSAKANSPDLVLMDVGLP
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCC
DTDGREVVRSLRKGGFKAPIIMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHH
LRQHEASEDAVFTVGPYSFRPGSKMLTGANAKKVRLTEKETAILRFLYRAGQAPVSRETL
HHHCCCCCCCEEEECCCCCCCCCCEEECCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]